CREB5.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CREB5.H12INVITRO.0.P.B
Gene (human)	CREB5 (GeneCards)
Gene synonyms (human)	CREBPA
Gene (mouse)	Creb5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	nRTGAKGTMAK
GC content	36.05%
Information content (bits; total / per base)	11.335 / 1.03
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (10)	0.767	0.833	0.701	0.781	0.753	0.816	2.758	3.179	140.833	214.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.954	0.935	0.908	0.888	0.824	0.813
Overall, 6 experiments	best	1.0	0.999	0.999	0.998	0.993	0.991
Methyl HT-SELEX, 2 experiments	median	0.997	0.996	0.993	0.99	0.958	0.954
Methyl HT-SELEX, 2 experiments	best	1.0	0.999	0.999	0.998	0.993	0.991
Non-Methyl HT-SELEX, 4 experiments	median	0.841	0.824	0.722	0.717	0.638	0.644
Non-Methyl HT-SELEX, 4 experiments	best	0.995	0.992	0.991	0.986	0.983	0.975

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.842	0.428	0.348	0.189
batch 2	0.892	0.795	0.453	0.288

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	ATF2 {1.1.1.3} (TFClass)
TFClass ID	TFClass: 1.1.1.3.3
HGNC	HGNC:16844
MGI	MGI:2443973
EntrezGene (human)	GeneID:9586 (SSTAR profile)
EntrezGene (mouse)	GeneID:231991 (SSTAR profile)
UniProt ID (human)	CREB5_HUMAN
UniProt ID (mouse)	CREB5_MOUSE
UniProt AC (human)	Q02930 (TFClass)
UniProt AC (mouse)	Q8K1L0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	CREB5.H12INVITRO.0.P.B.pcm
PWM	CREB5.H12INVITRO.0.P.B.pwm
PFM	CREB5.H12INVITRO.0.P.B.pfm
Alignment	CREB5.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	CREB5.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	CREB5.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	CREB5.H12INVITRO.0.P.B_meme_format.meme
Transfac format	CREB5.H12INVITRO.0.P.B_transfac_format.txt
Homer format	CREB5.H12INVITRO.0.P.B_homer_format_0.001.txt CREB5.H12INVITRO.0.P.B_homer_format_0.0005.txt CREB5.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	346.0	159.0	319.0	176.0
02	662.0	115.0	181.0	42.0
03	39.0	6.0	11.0	944.0
04	3.0	11.0	806.0	180.0
05	914.0	29.0	26.0	31.0
06	76.0	38.0	263.0	623.0
07	14.0	117.0	824.0	45.0
08	21.0	104.0	27.0	848.0
09	297.0	667.0	11.0	25.0
10	970.0	13.0	2.0	15.0
11	30.0	117.0	119.0	734.0

PFM

	A	C	G	T
01	0.346	0.159	0.319	0.176
02	0.662	0.115	0.181	0.042
03	0.039	0.006	0.011	0.944
04	0.003	0.011	0.806	0.18
05	0.914	0.029	0.026	0.031
06	0.076	0.038	0.263	0.623
07	0.014	0.117	0.824	0.045
08	0.021	0.104	0.027	0.848
09	0.297	0.667	0.011	0.025
10	0.97	0.013	0.002	0.015
11	0.03	0.117	0.119	0.734

PWM

	A	C	G	T
01	0.323	-0.449	0.242	-0.348
02	0.97	-0.769	-0.32	-1.75
03	-1.821	-3.484	-2.985	1.324
04	-3.975	-2.985	1.166	-0.326
05	1.291	-2.103	-2.206	-2.04
06	-1.175	-1.846	0.05	0.909
07	-2.773	-0.752	1.188	-1.684
08	-2.405	-0.867	-2.171	1.217
09	0.171	0.977	-2.985	-2.243
10	1.351	-2.839	-4.213	-2.711
11	-2.071	-0.752	-0.735	1.073

Standard thresholds

P-value	Threshold
0.001	4.375965
0.0005	5.31567
0.0001	7.21124