MotifCREB3.H12INVIVO.0.SM.D
Gene (human)CREB3
(GeneCards)
Gene synonyms (human)LZIP
Gene (mouse)Creb3
Gene synonyms (mouse)Lzip
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length14
ConsensusndSRTGACGTGRMn
GC content57.01%
Information content (bits; total / per base)15.735 / 1.124
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words410

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.886 0.88 0.778 0.777 0.677 0.687
best 0.994 0.99 0.981 0.974 0.925 0.913
Methyl HT-SELEX, 1 experiments median 0.984 0.977 0.911 0.897 0.782 0.782
best 0.984 0.977 0.911 0.897 0.782 0.782
Non-Methyl HT-SELEX, 3 experiments median 0.788 0.783 0.646 0.657 0.572 0.592
best 0.994 0.99 0.981 0.974 0.925 0.913

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.825 0.739 0.843 0.66
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyCREB-related {1.1.7} (TFClass)
TF subfamilyCREB3-like {1.1.7.2} (TFClass)
TFClass IDTFClass: 1.1.7.2.1
HGNCHGNC:2347
MGIMGI:99946
EntrezGene (human)GeneID:10488
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)CREB3_HUMAN
UniProt ID (mouse)CREB3_MOUSE
UniProt AC (human)O43889
(TFClass)
UniProt AC (mouse)Q61817
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
0179.575.5153.5101.5
02105.7530.7594.75178.75
0357.068.0250.035.0
04188.014.0207.01.0
050.05.01.0404.0
060.05.0404.01.0
07410.00.00.00.0
080.0410.00.00.0
090.00.0410.00.0
100.01.00.0409.0
112.0131.0277.00.0
12143.00.0246.021.0
1368.25266.2515.2560.25
14134.7584.75122.7567.75
PFM
ACGT
010.1940.1840.3740.248
020.2580.0750.2310.436
030.1390.1660.610.085
040.4590.0340.5050.002
050.00.0120.0020.985
060.00.0120.9850.002
071.00.00.00.0
080.01.00.00.0
090.00.01.00.0
100.00.0020.00.998
110.0050.320.6760.0
120.3490.00.60.051
130.1660.6490.0370.147
140.3290.2070.2990.165
PWM
ACGT
01-0.25-0.3010.399-0.01
020.031-1.171-0.0770.55
03-0.575-0.4030.883-1.047
040.6-1.9030.696-3.727
05-4.236-2.772-3.7271.361
06-4.236-2.7721.361-3.727
071.375-4.236-4.236-4.236
08-4.2361.375-4.236-4.236
09-4.236-4.2361.375-4.236
10-4.236-3.727-4.2361.373
11-3.3910.2420.985-4.236
120.329-4.2360.867-1.531
13-0.3990.946-1.826-0.521
140.27-0.1870.178-0.407
Standard thresholds
P-value Threshold
0.001 1.84571
0.0005 3.43951
0.0001 6.11506