CR3L1.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CR3L1.H12INVIVO.0.PSM.A
Gene (human)	CREB3L1 (GeneCards)
Gene synonyms (human)	OASIS
Gene (mouse)	Creb3l1
Gene synonyms (mouse)	Oasis
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	14
Consensus	ndnhbACGTGGCdn
GC content	59.17%
Information content (bits; total / per base)	13.817 / 0.987
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9283

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.756	0.79	0.686	0.726	0.707	0.749	2.429	2.715	68.469	103.585

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 9 experiments	median	0.997	0.995	0.968	0.959	0.911	0.897
Overall, 9 experiments	best	1.0	0.999	0.999	0.999	0.992	0.991
Methyl HT-SELEX, 2 experiments	median	0.996	0.994	0.982	0.977	0.941	0.931
Methyl HT-SELEX, 2 experiments	best	0.999	0.997	0.996	0.994	0.971	0.966
Non-Methyl HT-SELEX, 7 experiments	median	0.997	0.995	0.922	0.922	0.753	0.777
Non-Methyl HT-SELEX, 7 experiments	best	1.0	0.999	0.999	0.999	0.992	0.991

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	CREB-related {1.1.7} (TFClass)
TF subfamily	CREB3-like {1.1.7.2} (TFClass)
TFClass ID	TFClass: 1.1.7.2.2
HGNC	HGNC:18856
MGI	MGI:1347062
EntrezGene (human)	GeneID:90993 (SSTAR profile)
EntrezGene (mouse)	GeneID:26427 (SSTAR profile)
UniProt ID (human)	CR3L1_HUMAN
UniProt ID (mouse)	CR3L1_MOUSE
UniProt AC (human)	Q96BA8 (TFClass)
UniProt AC (mouse)	Q9Z125 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	7
Methyl-HT-SELEX	2

PCM	CR3L1.H12INVIVO.0.PSM.A.pcm
PWM	CR3L1.H12INVIVO.0.PSM.A.pwm
PFM	CR3L1.H12INVIVO.0.PSM.A.pfm
Alignment	CR3L1.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	CR3L1.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	CR3L1.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	CR3L1.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	CR3L1.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	CR3L1.H12INVIVO.0.PSM.A_homer_format_0.001.txt CR3L1.H12INVIVO.0.PSM.A_homer_format_0.0005.txt CR3L1.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2279.25	1833.25	2208.25	2962.25
02	1696.5	1243.5	4377.5	1965.5
03	2190.0	1660.0	3264.0	2169.0
04	2941.0	3133.0	825.0	2384.0
05	981.0	4000.0	1904.0	2398.0
06	8989.0	13.0	161.0	120.0
07	2.0	9262.0	6.0	13.0
08	0.0	0.0	9281.0	2.0
09	2.0	0.0	0.0	9281.0
10	5.0	1.0	9277.0	0.0
11	14.0	77.0	8817.0	375.0
12	429.0	8529.0	116.0	209.0
13	5390.75	964.75	1679.75	1247.75
14	1829.0	2436.0	1829.0	3189.0

PFM

	A	C	G	T
01	0.246	0.197	0.238	0.319
02	0.183	0.134	0.472	0.212
03	0.236	0.179	0.352	0.234
04	0.317	0.337	0.089	0.257
05	0.106	0.431	0.205	0.258
06	0.968	0.001	0.017	0.013
07	0.0	0.998	0.001	0.001
08	0.0	0.0	1.0	0.0
09	0.0	0.0	0.0	1.0
10	0.001	0.0	0.999	0.0
11	0.002	0.008	0.95	0.04
12	0.046	0.919	0.012	0.023
13	0.581	0.104	0.181	0.134
14	0.197	0.262	0.197	0.344

PWM

	A	C	G	T
01	-0.018	-0.236	-0.05	0.244
02	-0.313	-0.623	0.634	-0.166
03	-0.058	-0.335	0.341	-0.068
04	0.237	0.3	-1.032	0.027
05	-0.86	0.544	-0.198	0.033
06	1.353	-5.024	-2.655	-2.944
07	-6.296	1.383	-5.636	-5.024
08	-6.925	-6.925	1.385	-6.296
09	-6.296	-6.925	-6.925	1.385
10	-5.765	-6.562	1.385	-6.925
11	-4.96	-3.378	1.334	-1.818
12	-1.684	1.301	-2.978	-2.397
13	0.842	-0.876	-0.323	-0.62
14	-0.238	0.048	-0.238	0.318

Standard thresholds

P-value	Threshold
0.001	2.00426
0.0005	3.63491
0.0001	6.71441