COT2.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	COT2.H12CORE.0.P.B
Gene (human)	NR2F2 (GeneCards)
Gene synonyms (human)	ARP1, TFCOUP2
Gene (mouse)	Nr2f2
Gene synonyms (mouse)	Aporp1, Arp-1, Arp1, Tfcoup2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	ddRvbnWRAGGTCA
GC content	54.99%
Information content (bits; total / per base)	11.601 / 0.829
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	11 (75)	0.812	0.88	0.693	0.796	0.783	0.868	2.634	3.532	121.699	237.886
Mouse	1 (7)	0.701	0.724	0.611	0.638	0.688	0.709	2.562	2.706	54.569	69.77

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	RXR-related receptors {2.1.3} (TFClass)
TF subfamily	COUP (NR2F) {2.1.3.5} (TFClass)
TFClass ID	TFClass: 2.1.3.5.2
HGNC	HGNC:7976
MGI	MGI:1352452
EntrezGene (human)	GeneID:7026 (SSTAR profile)
EntrezGene (mouse)	GeneID:11819 (SSTAR profile)
UniProt ID (human)	COT2_HUMAN
UniProt ID (mouse)	COT2_MOUSE
UniProt AC (human)	P24468 (TFClass)
UniProt AC (mouse)	P43135 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	11 human, 1 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	COT2.H12CORE.0.P.B.pcm
PWM	COT2.H12CORE.0.P.B.pwm
PFM	COT2.H12CORE.0.P.B.pfm
Alignment	COT2.H12CORE.0.P.B.words.tsv
Threshold to P-value map	COT2.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	COT2.H12CORE.0.P.B_jaspar_format.txt
MEME format	COT2.H12CORE.0.P.B_meme_format.meme
Transfac format	COT2.H12CORE.0.P.B_transfac_format.txt
Homer format	COT2.H12CORE.0.P.B_homer_format_0.001.txt COT2.H12CORE.0.P.B_homer_format_0.0005.txt COT2.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	337.0	126.0	403.0	134.0
02	371.0	64.0	467.0	98.0
03	159.0	99.0	619.0	123.0
04	167.0	156.0	571.0	106.0
05	107.0	280.0	219.0	394.0
06	162.0	562.0	114.0	162.0
07	694.25	98.25	88.25	119.25
08	459.25	38.25	465.25	37.25
09	720.25	3.25	269.25	7.25
10	23.25	2.25	958.25	16.25
11	13.25	3.25	959.25	24.25
12	6.25	56.25	120.25	817.25
13	9.25	879.25	50.25	61.25
14	953.25	9.25	17.25	20.25

PFM

	A	C	G	T
01	0.337	0.126	0.403	0.134
02	0.371	0.064	0.467	0.098
03	0.159	0.099	0.619	0.123
04	0.167	0.156	0.571	0.106
05	0.107	0.28	0.219	0.394
06	0.162	0.562	0.114	0.162
07	0.694	0.098	0.088	0.119
08	0.459	0.038	0.465	0.037
09	0.72	0.003	0.269	0.007
10	0.023	0.002	0.958	0.016
11	0.013	0.003	0.959	0.024
12	0.006	0.056	0.12	0.817
13	0.009	0.879	0.05	0.061
14	0.953	0.009	0.017	0.02

PWM

	A	C	G	T
01	0.297	-0.678	0.475	-0.618
02	0.393	-1.343	0.622	-0.926
03	-0.449	-0.916	0.903	-0.702
04	-0.4	-0.467	0.822	-0.849
05	-0.84	0.113	-0.131	0.452
06	-0.43	0.806	-0.777	-0.43
07	1.017	-0.923	-1.029	-0.733
08	0.605	-1.84	0.618	-1.865
09	1.054	-3.924	0.074	-3.334
10	-2.31	-4.148	1.339	-2.639
11	-2.822	-3.924	1.34	-2.271
12	-3.452	-1.468	-0.725	1.18
13	-3.133	1.253	-1.578	-1.386
14	1.333	-3.133	-2.585	-2.438

Standard thresholds

P-value	Threshold
0.001	4.31866
0.0005	5.26681
0.0001	7.21506