Motif | COT1.H12RSNP.1.PSM.A |
Gene (human) | NR2F1 (GeneCards) |
Gene synonyms (human) | EAR3, ERBAL3, TFCOUP1 |
Gene (mouse) | Nr2f1 |
Gene synonyms (mouse) | Erbal3, Tfcoup1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif | COT1.H12RSNP.1.PSM.A |
Gene (human) | NR2F1 (GeneCards) |
Gene synonyms (human) | EAR3, ERBAL3, TFCOUP1 |
Gene (mouse) | Nr2f1 |
Gene synonyms (mouse) | Erbal3, Tfcoup1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif length | 16 |
Consensus | dRGKYCAAAGGTCAnn |
GC content | 49.79% |
Information content (bits; total / per base) | 18.652 / 1.166 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 1551 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 5 (34) | 0.858 | 0.895 | 0.767 | 0.836 | 0.821 | 0.86 | 2.929 | 3.683 | 139.58 | 214.215 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.999 | 0.998 | 0.974 | 0.971 | 0.93 | 0.92 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 0.989 | 0.987 | |
Methyl HT-SELEX, 2 experiments | median | 1.0 | 1.0 | 0.998 | 0.997 | 0.977 | 0.974 |
best | 1.0 | 1.0 | 0.999 | 0.999 | 0.979 | 0.975 | |
Non-Methyl HT-SELEX, 6 experiments | median | 0.995 | 0.994 | 0.952 | 0.944 | 0.886 | 0.861 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 0.989 | 0.987 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 2.769 | 6.801 | 0.152 | 0.097 |
TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
TF family | RXR-related receptors {2.1.3} (TFClass) |
TF subfamily | COUP (NR2F) {2.1.3.5} (TFClass) |
TFClass ID | TFClass: 2.1.3.5.1 |
HGNC | HGNC:7975 |
MGI | MGI:1352451 |
EntrezGene (human) | GeneID:7025 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13865 (SSTAR profile) |
UniProt ID (human) | COT1_HUMAN |
UniProt ID (mouse) | COT1_MOUSE |
UniProt AC (human) | P10589 (TFClass) |
UniProt AC (mouse) | Q60632 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 5 human, 0 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 2 |
PCM | COT1.H12RSNP.1.PSM.A.pcm |
PWM | COT1.H12RSNP.1.PSM.A.pwm |
PFM | COT1.H12RSNP.1.PSM.A.pfm |
Alignment | COT1.H12RSNP.1.PSM.A.words.tsv |
Threshold to P-value map | COT1.H12RSNP.1.PSM.A.thr |
Motif in other formats | |
JASPAR format | COT1.H12RSNP.1.PSM.A_jaspar_format.txt |
MEME format | COT1.H12RSNP.1.PSM.A_meme_format.meme |
Transfac format | COT1.H12RSNP.1.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 532.0 | 190.0 | 614.0 | 215.0 |
02 | 612.25 | 63.25 | 812.25 | 63.25 |
03 | 45.0 | 59.0 | 1359.0 | 88.0 |
04 | 44.0 | 73.0 | 1109.0 | 325.0 |
05 | 49.0 | 343.0 | 50.0 | 1109.0 |
06 | 310.0 | 1175.0 | 25.0 | 41.0 |
07 | 1450.0 | 35.0 | 18.0 | 48.0 |
08 | 1318.0 | 12.0 | 144.0 | 77.0 |
09 | 1477.0 | 0.0 | 73.0 | 1.0 |
10 | 0.0 | 0.0 | 1549.0 | 2.0 |
11 | 0.0 | 0.0 | 1551.0 | 0.0 |
12 | 0.0 | 1.0 | 4.0 | 1546.0 |
13 | 0.0 | 1501.0 | 17.0 | 33.0 |
14 | 1437.0 | 7.0 | 100.0 | 7.0 |
15 | 571.75 | 369.75 | 212.75 | 396.75 |
16 | 387.75 | 310.75 | 578.75 | 273.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.343 | 0.123 | 0.396 | 0.139 |
02 | 0.395 | 0.041 | 0.524 | 0.041 |
03 | 0.029 | 0.038 | 0.876 | 0.057 |
04 | 0.028 | 0.047 | 0.715 | 0.21 |
05 | 0.032 | 0.221 | 0.032 | 0.715 |
06 | 0.2 | 0.758 | 0.016 | 0.026 |
07 | 0.935 | 0.023 | 0.012 | 0.031 |
08 | 0.85 | 0.008 | 0.093 | 0.05 |
09 | 0.952 | 0.0 | 0.047 | 0.001 |
10 | 0.0 | 0.0 | 0.999 | 0.001 |
11 | 0.0 | 0.0 | 1.0 | 0.0 |
12 | 0.0 | 0.001 | 0.003 | 0.997 |
13 | 0.0 | 0.968 | 0.011 | 0.021 |
14 | 0.926 | 0.005 | 0.064 | 0.005 |
15 | 0.369 | 0.238 | 0.137 | 0.256 |
16 | 0.25 | 0.2 | 0.373 | 0.176 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.315 | -0.708 | 0.458 | -0.586 |
02 | 0.455 | -1.789 | 0.737 | -1.789 |
03 | -2.118 | -1.857 | 1.251 | -1.467 |
04 | -2.14 | -1.65 | 1.048 | -0.176 |
05 | -2.036 | -0.122 | -2.017 | 1.048 |
06 | -0.223 | 1.105 | -2.675 | -2.208 |
07 | 1.315 | -2.359 | -2.978 | -2.056 |
08 | 1.22 | -3.338 | -0.983 | -1.598 |
09 | 1.334 | -5.357 | -1.65 | -4.922 |
10 | -5.357 | -5.357 | 1.381 | -4.62 |
11 | -5.357 | -5.357 | 1.383 | -5.357 |
12 | -5.357 | -4.922 | -4.201 | 1.38 |
13 | -5.357 | 1.35 | -3.029 | -2.414 |
14 | 1.307 | -3.786 | -1.342 | -3.786 |
15 | 0.387 | -0.047 | -0.596 | 0.023 |
16 | 0.0 | -0.22 | 0.399 | -0.346 |
P-value | Threshold |
---|---|
0.001 | 0.22731 |
0.0005 | 1.76991 |
0.0001 | 4.97871 |