Motif | COT1.H12CORE.0.PSM.A |
Gene (human) | NR2F1 (GeneCards) |
Gene synonyms (human) | EAR3, ERBAL3, TFCOUP1 |
Gene (mouse) | Nr2f1 |
Gene synonyms (mouse) | Erbal3, Tfcoup1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | COT1.H12CORE.0.PSM.A |
Gene (human) | NR2F1 (GeneCards) |
Gene synonyms (human) | EAR3, ERBAL3, TFCOUP1 |
Gene (mouse) | Nr2f1 |
Gene synonyms (mouse) | Erbal3, Tfcoup1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 10 |
Consensus | ndRGGTCAnn |
GC content | 52.95% |
Information content (bits; total / per base) | 9.29 / 0.929 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9822 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 5 (34) | 0.873 | 0.915 | 0.763 | 0.84 | 0.837 | 0.893 | 2.624 | 3.115 | 177.361 | 321.102 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.997 | 0.995 | 0.987 | 0.983 | 0.959 | 0.95 |
best | 1.0 | 1.0 | 0.998 | 0.998 | 0.991 | 0.988 | |
Methyl HT-SELEX, 2 experiments | median | 0.997 | 0.996 | 0.993 | 0.99 | 0.98 | 0.974 |
best | 0.999 | 0.998 | 0.995 | 0.993 | 0.982 | 0.974 | |
Non-Methyl HT-SELEX, 6 experiments | median | 0.997 | 0.995 | 0.976 | 0.971 | 0.934 | 0.915 |
best | 1.0 | 1.0 | 0.998 | 0.998 | 0.991 | 0.988 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 2.506 | 5.744 | 0.185 | 0.103 |
TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
TF family | RXR-related receptors {2.1.3} (TFClass) |
TF subfamily | COUP (NR2F) {2.1.3.5} (TFClass) |
TFClass ID | TFClass: 2.1.3.5.1 |
HGNC | HGNC:7975 |
MGI | MGI:1352451 |
EntrezGene (human) | GeneID:7025 (SSTAR profile) |
EntrezGene (mouse) | GeneID:13865 (SSTAR profile) |
UniProt ID (human) | COT1_HUMAN |
UniProt ID (mouse) | COT1_MOUSE |
UniProt AC (human) | P10589 (TFClass) |
UniProt AC (mouse) | Q60632 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 5 human, 0 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 2 |
PCM | COT1.H12CORE.0.PSM.A.pcm |
PWM | COT1.H12CORE.0.PSM.A.pwm |
PFM | COT1.H12CORE.0.PSM.A.pfm |
Alignment | COT1.H12CORE.0.PSM.A.words.tsv |
Threshold to P-value map | COT1.H12CORE.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | COT1.H12CORE.0.PSM.A_jaspar_format.txt |
MEME format | COT1.H12CORE.0.PSM.A_meme_format.meme |
Transfac format | COT1.H12CORE.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 3255.5 | 1973.5 | 2112.5 | 2480.5 |
02 | 3663.0 | 1028.0 | 3731.0 | 1400.0 |
03 | 5771.0 | 316.0 | 3264.0 | 471.0 |
04 | 5.0 | 89.0 | 9618.0 | 110.0 |
05 | 0.0 | 14.0 | 9776.0 | 32.0 |
06 | 17.0 | 10.0 | 87.0 | 9708.0 |
07 | 158.0 | 8995.0 | 371.0 | 298.0 |
08 | 8306.0 | 324.0 | 956.0 | 236.0 |
09 | 3365.75 | 2386.75 | 1828.75 | 2240.75 |
10 | 2976.25 | 1777.25 | 3351.25 | 1717.25 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.331 | 0.201 | 0.215 | 0.253 |
02 | 0.373 | 0.105 | 0.38 | 0.143 |
03 | 0.588 | 0.032 | 0.332 | 0.048 |
04 | 0.001 | 0.009 | 0.979 | 0.011 |
05 | 0.0 | 0.001 | 0.995 | 0.003 |
06 | 0.002 | 0.001 | 0.009 | 0.988 |
07 | 0.016 | 0.916 | 0.038 | 0.03 |
08 | 0.846 | 0.033 | 0.097 | 0.024 |
09 | 0.343 | 0.243 | 0.186 | 0.228 |
10 | 0.303 | 0.181 | 0.341 | 0.175 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.282 | -0.218 | -0.15 | 0.01 |
02 | 0.4 | -0.869 | 0.418 | -0.561 |
03 | 0.854 | -2.044 | 0.284 | -1.647 |
04 | -5.819 | -3.293 | 1.365 | -3.086 |
05 | -6.975 | -5.016 | 1.381 | -4.272 |
06 | -4.847 | -5.298 | -3.315 | 1.374 |
07 | -2.73 | 1.298 | -1.885 | -2.102 |
08 | 1.218 | -2.019 | -0.942 | -2.333 |
09 | 0.315 | -0.028 | -0.294 | -0.091 |
10 | 0.192 | -0.323 | 0.311 | -0.357 |
P-value | Threshold |
---|---|
0.001 | 4.8738 |
0.0005 | 5.871465 |
0.0001 | 7.67062 |