COE1.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	COE1.H12RSNP.0.P.B
Gene (human)	EBF1 (GeneCards)
Gene synonyms (human)	COE1, EBF
Gene (mouse)	Ebf1
Gene synonyms (mouse)	Coe1, Ebf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	dbTCCCYWGGGRvh
GC content	64.29%
Information content (bits; total / per base)	14.671 / 1.048
Data sources	ChIP-Seq
Aligned words	985

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (55)	0.954	0.974	0.906	0.941	0.924	0.951	3.888	4.113	467.301	669.824
Mouse	31 (199)	0.953	0.983	0.912	0.96	0.921	0.967	4.042	4.756	386.959	885.959

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	15.715	13.568	0.411	0.359

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Rel homology region (RHR) factors {6.1} (TFClass)
TF family	EBF-related {6.1.5} (TFClass)
TF subfamily	{6.1.5.0} (TFClass)
TFClass ID	TFClass: 6.1.5.0.1
HGNC	HGNC:3126
MGI	MGI:95275
EntrezGene (human)	GeneID:1879 (SSTAR profile)
EntrezGene (mouse)	GeneID:13591 (SSTAR profile)
UniProt ID (human)	COE1_HUMAN
UniProt ID (mouse)	COE1_MOUSE
UniProt AC (human)	Q9UH73 (TFClass)
UniProt AC (mouse)	Q07802 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 31 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	COE1.H12RSNP.0.P.B.pcm
PWM	COE1.H12RSNP.0.P.B.pwm
PFM	COE1.H12RSNP.0.P.B.pfm
Alignment	COE1.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	COE1.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	COE1.H12RSNP.0.P.B_jaspar_format.txt
MEME format	COE1.H12RSNP.0.P.B_meme_format.meme
Transfac format	COE1.H12RSNP.0.P.B_transfac_format.txt
Homer format	COE1.H12RSNP.0.P.B_homer_format_0.001.txt COE1.H12RSNP.0.P.B_homer_format_0.0005.txt COE1.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	351.0	84.0	290.0	260.0
02	118.0	212.0	430.0	225.0
03	14.0	113.0	31.0	827.0
04	4.0	967.0	8.0	6.0
05	1.25	885.25	0.25	98.25
06	8.25	961.25	1.25	14.25
07	47.25	675.25	18.25	244.25
08	452.25	24.25	7.25	501.25
09	3.25	3.25	976.25	2.25
10	151.25	0.25	821.25	12.25
11	5.25	2.25	972.25	5.25
12	726.25	10.25	216.25	32.25
13	177.25	451.25	261.25	95.25
14	160.25	339.25	104.25	381.25

PFM

	A	C	G	T
01	0.356	0.085	0.294	0.264
02	0.12	0.215	0.437	0.228
03	0.014	0.115	0.031	0.84
04	0.004	0.982	0.008	0.006
05	0.001	0.899	0.0	0.1
06	0.008	0.976	0.001	0.014
07	0.048	0.686	0.019	0.248
08	0.459	0.025	0.007	0.509
09	0.003	0.003	0.991	0.002
10	0.154	0.0	0.834	0.012
11	0.005	0.002	0.987	0.005
12	0.737	0.01	0.22	0.033
13	0.18	0.458	0.265	0.097
14	0.163	0.344	0.106	0.387

PWM

	A	C	G	T
01	0.352	-1.062	0.162	0.054
02	-0.728	-0.149	0.554	-0.09
03	-2.758	-0.771	-2.025	1.207
04	-3.769	1.363	-3.239	-3.469
05	-4.424	1.274	-4.834	-0.908
06	-3.213	1.357	-4.424	-2.742
07	-1.622	1.004	-2.519	-0.008
08	0.605	-2.256	-3.319	0.707
09	-3.909	-3.909	1.372	-4.134
10	-0.483	-4.834	1.2	-2.876
11	-3.571	-4.134	1.368	-3.571
12	1.077	-3.031	-0.129	-1.988
13	-0.326	0.603	0.059	-0.939
14	-0.426	0.318	-0.85	0.435

Standard thresholds

P-value	Threshold
0.001	2.73926
0.0005	4.00491
0.0001	6.61541