CEBPG.H12RSNP.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPG.H12RSNP.2.P.B
Gene (human)	CEBPG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	13
Consensus	dRTTGCATCAYhh
GC content	40.27%
Information content (bits; total / per base)	15.46 / 1.189
Data sources	ChIP-Seq
Aligned words	779

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.901	0.965	0.804	0.942	0.861	0.953	3.668	5.282	444.174	724.013
Mouse	1 (7)	0.967	0.968	0.952	0.954	0.956	0.958	4.892	4.901	653.553	751.721

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.964	0.939	0.945	0.915	0.837	0.827
Overall, 8 experiments	best	0.985	0.974	0.979	0.965	0.969	0.951
Methyl HT-SELEX, 2 experiments	median	0.976	0.959	0.964	0.943	0.924	0.903
Methyl HT-SELEX, 2 experiments	best	0.985	0.974	0.979	0.965	0.969	0.951
Non-Methyl HT-SELEX, 6 experiments	median	0.921	0.887	0.824	0.802	0.706	0.713
Non-Methyl HT-SELEX, 6 experiments	best	0.978	0.963	0.968	0.948	0.95	0.925

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.173	2.27	0.215	0.122

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.3
HGNC	HGNC:1837
MGI	MGI:104982
EntrezGene (human)	GeneID:1054 (SSTAR profile)
EntrezGene (mouse)	GeneID:12611 (SSTAR profile)
UniProt ID (human)	CEBPG_HUMAN
UniProt ID (mouse)	CEBPG_MOUSE
UniProt AC (human)	P53567 (TFClass)
UniProt AC (mouse)	P53568 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 1 mouse
HT-SELEX	6
Methyl-HT-SELEX	2

PCM	CEBPG.H12RSNP.2.P.B.pcm
PWM	CEBPG.H12RSNP.2.P.B.pwm
PFM	CEBPG.H12RSNP.2.P.B.pfm
Alignment	CEBPG.H12RSNP.2.P.B.words.tsv
Threshold to P-value map	CEBPG.H12RSNP.2.P.B.thr
Motif in other formats
JASPAR format	CEBPG.H12RSNP.2.P.B_jaspar_format.txt
MEME format	CEBPG.H12RSNP.2.P.B_meme_format.meme
Transfac format	CEBPG.H12RSNP.2.P.B_transfac_format.txt
Homer format	CEBPG.H12RSNP.2.P.B_homer_format_0.001.txt CEBPG.H12RSNP.2.P.B_homer_format_0.0005.txt CEBPG.H12RSNP.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	120.0	116.0	289.0	254.0
02	471.0	67.0	233.0	8.0
03	0.0	0.0	0.0	779.0
04	0.0	0.0	0.0	779.0
05	51.0	0.0	604.0	124.0
06	0.0	778.0	0.0	1.0
07	672.0	8.0	90.0	9.0
08	23.0	14.0	2.0	740.0
09	34.0	744.0	1.0	0.0
10	779.0	0.0	0.0	0.0
11	4.0	166.0	134.0	475.0
12	132.0	364.0	93.0	190.0
13	129.0	287.0	88.0	275.0

PFM

	A	C	G	T
01	0.154	0.149	0.371	0.326
02	0.605	0.086	0.299	0.01
03	0.0	0.0	0.0	1.0
04	0.0	0.0	0.0	1.0
05	0.065	0.0	0.775	0.159
06	0.0	0.999	0.0	0.001
07	0.863	0.01	0.116	0.012
08	0.03	0.018	0.003	0.95
09	0.044	0.955	0.001	0.0
10	1.0	0.0	0.0	0.0
11	0.005	0.213	0.172	0.61
12	0.169	0.467	0.119	0.244
13	0.166	0.368	0.113	0.353

PWM

	A	C	G	T
01	-0.479	-0.512	0.392	0.264
02	0.878	-1.051	0.178	-3.012
03	-4.771	-4.771	-4.771	1.38
04	-4.771	-4.771	-4.771	1.38
05	-1.316	-4.771	1.126	-0.447
06	-4.771	1.379	-4.771	-4.3
07	1.233	-3.012	-0.762	-2.913
08	-2.075	-2.529	-3.982	1.329
09	-1.706	1.334	-4.3	-4.771
10	1.38	-4.771	-4.771	-4.771
11	-3.546	-0.158	-0.37	0.887
12	-0.385	0.621	-0.73	-0.024
13	-0.408	0.385	-0.784	0.343

Standard thresholds

P-value	Threshold
0.001	1.853515
0.0005	3.317315
0.0001	6.239675