CEBPG.H12RSNP.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPG.H12RSNP.1.SM.B
Gene (human)	CEBPG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	ndATTGCGThd
GC content	45.28%
Information content (bits; total / per base)	11.435 / 1.04
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9184

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.937	0.959	0.883	0.926	0.886	0.922	3.43	3.982	603.237	906.102
Mouse	1 (7)	0.901	0.906	0.828	0.831	0.792	0.797	2.271	2.301	450.328	508.77

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.967	0.945	0.944	0.916	0.849	0.842
Overall, 8 experiments	best	0.997	0.994	0.989	0.982	0.971	0.961
Methyl HT-SELEX, 2 experiments	median	0.981	0.969	0.968	0.951	0.934	0.915
Methyl HT-SELEX, 2 experiments	best	0.994	0.99	0.989	0.982	0.971	0.961
Non-Methyl HT-SELEX, 6 experiments	median	0.939	0.918	0.856	0.838	0.725	0.743
Non-Methyl HT-SELEX, 6 experiments	best	0.997	0.994	0.983	0.973	0.963	0.948

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	13.446	14.076	0.347	0.232

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.3
HGNC	HGNC:1837
MGI	MGI:104982
EntrezGene (human)	GeneID:1054 (SSTAR profile)
EntrezGene (mouse)	GeneID:12611 (SSTAR profile)
UniProt ID (human)	CEBPG_HUMAN
UniProt ID (mouse)	CEBPG_MOUSE
UniProt AC (human)	P53567 (TFClass)
UniProt AC (mouse)	P53568 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 1 mouse
HT-SELEX	6
Methyl-HT-SELEX	2

PCM	CEBPG.H12RSNP.1.SM.B.pcm
PWM	CEBPG.H12RSNP.1.SM.B.pwm
PFM	CEBPG.H12RSNP.1.SM.B.pfm
Alignment	CEBPG.H12RSNP.1.SM.B.words.tsv
Threshold to P-value map	CEBPG.H12RSNP.1.SM.B.thr
Motif in other formats
JASPAR format	CEBPG.H12RSNP.1.SM.B_jaspar_format.txt
MEME format	CEBPG.H12RSNP.1.SM.B_meme_format.meme
Transfac format	CEBPG.H12RSNP.1.SM.B_transfac_format.txt
Homer format	CEBPG.H12RSNP.1.SM.B_homer_format_0.001.txt CEBPG.H12RSNP.1.SM.B_homer_format_0.0005.txt CEBPG.H12RSNP.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2060.0	3150.0	2021.0	1953.0
02	1535.0	1432.0	3341.0	2876.0
03	7043.0	445.0	1687.0	9.0
04	0.0	0.0	0.0	9184.0
05	0.0	0.0	0.0	9184.0
06	971.0	1.0	8206.0	6.0
07	3.0	9171.0	0.0	10.0
08	998.0	68.0	8063.0	55.0
09	297.0	1677.0	104.0	7106.0
10	4343.25	1754.25	1518.25	1568.25
11	4515.5	1538.5	1564.5	1565.5

PFM

	A	C	G	T
01	0.224	0.343	0.22	0.213
02	0.167	0.156	0.364	0.313
03	0.767	0.048	0.184	0.001
04	0.0	0.0	0.0	1.0
05	0.0	0.0	0.0	1.0
06	0.106	0.0	0.894	0.001
07	0.0	0.999	0.0	0.001
08	0.109	0.007	0.878	0.006
09	0.032	0.183	0.011	0.774
10	0.473	0.191	0.165	0.171
11	0.492	0.168	0.17	0.17

PWM

	A	C	G	T
01	-0.108	0.316	-0.127	-0.162
02	-0.402	-0.471	0.375	0.225
03	1.12	-1.637	-0.308	-5.317
04	-6.915	-6.915	-6.915	1.386
05	-6.915	-6.915	-6.915	1.386
06	-0.859	-6.552	1.273	-5.626
07	-6.076	1.384	-6.915	-5.232
08	-0.832	-3.487	1.255	-3.692
09	-2.039	-0.314	-3.074	1.129
10	0.637	-0.269	-0.413	-0.381
11	0.676	-0.4	-0.383	-0.383

Standard thresholds

P-value	Threshold
0.001	4.10814
0.0005	5.480415
0.0001	7.62739