CEBPG.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPG.H12RSNP.0.P.B
Gene (human)	CEBPG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	bRTTGCRYAAYh
GC content	40.87%
Information content (bits; total / per base)	15.695 / 1.308
Data sources	ChIP-Seq
Aligned words	663

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.951	0.984	0.931	0.975	0.942	0.972	4.493	5.301	677.114	986.678
Mouse	1 (7)	0.856	0.858	0.787	0.793	0.739	0.74	2.003	2.023	326.569	368.456

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.977	0.959	0.958	0.936	0.851	0.85
Overall, 8 experiments	best	0.999	0.999	0.995	0.992	0.984	0.979
Methyl HT-SELEX, 2 experiments	median	0.988	0.98	0.978	0.967	0.94	0.927
Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.995	0.992	0.984	0.979
Non-Methyl HT-SELEX, 6 experiments	median	0.943	0.933	0.841	0.829	0.723	0.739
Non-Methyl HT-SELEX, 6 experiments	best	0.999	0.999	0.991	0.985	0.979	0.97

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	11.515	12.948	0.342	0.216

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.3
HGNC	HGNC:1837
MGI	MGI:104982
EntrezGene (human)	GeneID:1054 (SSTAR profile)
EntrezGene (mouse)	GeneID:12611 (SSTAR profile)
UniProt ID (human)	CEBPG_HUMAN
UniProt ID (mouse)	CEBPG_MOUSE
UniProt AC (human)	P53567 (TFClass)
UniProt AC (mouse)	P53568 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 1 mouse
HT-SELEX	6
Methyl-HT-SELEX	2

PCM	CEBPG.H12RSNP.0.P.B.pcm
PWM	CEBPG.H12RSNP.0.P.B.pwm
PFM	CEBPG.H12RSNP.0.P.B.pfm
Alignment	CEBPG.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	CEBPG.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	CEBPG.H12RSNP.0.P.B_jaspar_format.txt
MEME format	CEBPG.H12RSNP.0.P.B_meme_format.meme
Transfac format	CEBPG.H12RSNP.0.P.B_transfac_format.txt
Homer format	CEBPG.H12RSNP.0.P.B_homer_format_0.001.txt CEBPG.H12RSNP.0.P.B_homer_format_0.0005.txt CEBPG.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	48.0	105.0	216.0	294.0
02	473.0	39.0	150.0	1.0
03	0.0	0.0	0.0	663.0
04	0.0	0.0	0.0	663.0
05	0.0	0.0	663.0	0.0
06	0.0	663.0	0.0	0.0
07	232.0	15.0	392.0	24.0
08	27.0	465.0	1.0	170.0
09	638.0	25.0	0.0	0.0
10	663.0	0.0	0.0	0.0
11	7.0	284.0	10.0	362.0
12	248.0	200.0	24.0	191.0

PFM

	A	C	G	T
01	0.072	0.158	0.326	0.443
02	0.713	0.059	0.226	0.002
03	0.0	0.0	0.0	1.0
04	0.0	0.0	0.0	1.0
05	0.0	0.0	1.0	0.0
06	0.0	1.0	0.0	0.0
07	0.35	0.023	0.591	0.036
08	0.041	0.701	0.002	0.256
09	0.962	0.038	0.0	0.0
10	1.0	0.0	0.0	0.0
11	0.011	0.428	0.015	0.546
12	0.374	0.302	0.036	0.288

PWM

	A	C	G	T
01	-1.216	-0.451	0.263	0.569
02	1.042	-1.416	-0.099	-4.155
03	-4.635	-4.635	-4.635	1.379
04	-4.635	-4.635	-4.635	1.379
05	-4.635	-4.635	1.379	-4.635
06	-4.635	1.379	-4.635	-4.635
07	0.333	-2.309	0.855	-1.877
08	-1.766	1.025	-4.155	0.025
09	1.341	-1.838	-4.635	-4.635
10	1.379	-4.635	-4.635	-4.635
11	-2.966	0.534	-2.667	0.776
12	0.4	0.186	-1.877	0.141

Standard thresholds

P-value	Threshold
0.001	1.411435
0.0005	2.960525
0.0001	5.946025