CEBPG.H12INVIVO.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPG.H12INVIVO.2.P.B
Gene (human)	CEBPG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	12
Consensus	bRTTGCATCAYh
GC content	37.81%
Information content (bits; total / per base)	15.914 / 1.326
Data sources	ChIP-Seq
Aligned words	739

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.931	0.973	0.856	0.948	0.909	0.964	3.919	5.21	524.585	754.658
Mouse	1 (7)	0.976	0.978	0.957	0.959	0.952	0.956	4.632	4.64	664.131	758.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.966	0.942	0.948	0.92	0.845	0.837
Overall, 8 experiments	best	0.987	0.977	0.983	0.971	0.974	0.959
Methyl HT-SELEX, 2 experiments	median	0.978	0.962	0.967	0.948	0.933	0.913
Methyl HT-SELEX, 2 experiments	best	0.987	0.977	0.983	0.971	0.974	0.959
Non-Methyl HT-SELEX, 6 experiments	median	0.932	0.904	0.829	0.813	0.712	0.722
Non-Methyl HT-SELEX, 6 experiments	best	0.983	0.97	0.975	0.959	0.958	0.937

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.03	1.924	0.195	0.104

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.3
HGNC	HGNC:1837
MGI	MGI:104982
EntrezGene (human)	GeneID:1054 (SSTAR profile)
EntrezGene (mouse)	GeneID:12611 (SSTAR profile)
UniProt ID (human)	CEBPG_HUMAN
UniProt ID (mouse)	CEBPG_MOUSE
UniProt AC (human)	P53567 (TFClass)
UniProt AC (mouse)	P53568 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 1 mouse
HT-SELEX	6
Methyl-HT-SELEX	2

PCM	CEBPG.H12INVIVO.2.P.B.pcm
PWM	CEBPG.H12INVIVO.2.P.B.pwm
PFM	CEBPG.H12INVIVO.2.P.B.pfm
Alignment	CEBPG.H12INVIVO.2.P.B.words.tsv
Threshold to P-value map	CEBPG.H12INVIVO.2.P.B.thr
Motif in other formats
JASPAR format	CEBPG.H12INVIVO.2.P.B_jaspar_format.txt
MEME format	CEBPG.H12INVIVO.2.P.B_meme_format.meme
Transfac format	CEBPG.H12INVIVO.2.P.B_transfac_format.txt
Homer format	CEBPG.H12INVIVO.2.P.B_homer_format_0.001.txt CEBPG.H12INVIVO.2.P.B_homer_format_0.0005.txt CEBPG.H12INVIVO.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	84.0	87.0	280.0	288.0
02	535.0	39.0	163.0	2.0
03	0.0	0.0	0.0	739.0
04	0.0	0.0	1.0	738.0
05	24.0	0.0	636.0	79.0
06	0.0	739.0	0.0	0.0
07	672.0	4.0	56.0	7.0
08	13.0	47.0	2.0	677.0
09	66.0	672.0	1.0	0.0
10	736.0	0.0	2.0	1.0
11	3.0	158.0	74.0	504.0
12	146.0	321.0	71.0	201.0

PFM

	A	C	G	T
01	0.114	0.118	0.379	0.39
02	0.724	0.053	0.221	0.003
03	0.0	0.0	0.0	1.0
04	0.0	0.0	0.001	0.999
05	0.032	0.0	0.861	0.107
06	0.0	1.0	0.0	0.0
07	0.909	0.005	0.076	0.009
08	0.018	0.064	0.003	0.916
09	0.089	0.909	0.001	0.0
10	0.996	0.0	0.003	0.001
11	0.004	0.214	0.1	0.682
12	0.198	0.434	0.096	0.272

PWM

	A	C	G	T
01	-0.778	-0.743	0.413	0.441
02	1.057	-1.523	-0.124	-3.933
03	-4.726	-4.726	-4.726	1.38
04	-4.726	-4.726	-4.253	1.378
05	-1.983	-4.726	1.23	-0.838
06	-4.726	1.38	-4.726	-4.726
07	1.285	-3.496	-1.173	-3.07
08	-2.543	-1.343	-3.933	1.292
09	-1.014	1.285	-4.253	-4.726
10	1.376	-4.726	-3.933	-4.253
11	-3.691	-0.155	-0.902	0.998
12	-0.233	0.549	-0.942	0.084

Standard thresholds

P-value	Threshold
0.001	1.685065
0.0005	3.140565
0.0001	6.111955