CEBPG.H12CORE.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPG.H12CORE.1.SM.B
Gene (human)	CEBPG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	12
Consensus	bRTTGCGYAAbn
GC content	43.73%
Information content (bits; total / per base)	14.182 / 1.182
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9921

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.966	0.988	0.933	0.972	0.938	0.966	4.497	5.015	670.155	966.638
Mouse	1 (7)	0.905	0.908	0.829	0.835	0.791	0.793	2.193	2.213	365.699	414.745

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.98	0.966	0.963	0.944	0.861	0.86
Overall, 8 experiments	best	0.999	0.999	0.997	0.994	0.988	0.984
Methyl HT-SELEX, 2 experiments	median	0.991	0.984	0.982	0.973	0.955	0.943
Methyl HT-SELEX, 2 experiments	best	0.998	0.996	0.997	0.994	0.988	0.984
Non-Methyl HT-SELEX, 6 experiments	median	0.953	0.944	0.842	0.842	0.721	0.738
Non-Methyl HT-SELEX, 6 experiments	best	0.999	0.999	0.994	0.99	0.982	0.976

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	11.021	12.609	0.372	0.247

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.3
HGNC	HGNC:1837
MGI	MGI:104982
EntrezGene (human)	GeneID:1054 (SSTAR profile)
EntrezGene (mouse)	GeneID:12611 (SSTAR profile)
UniProt ID (human)	CEBPG_HUMAN
UniProt ID (mouse)	CEBPG_MOUSE
UniProt AC (human)	P53567 (TFClass)
UniProt AC (mouse)	P53568 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 1 mouse
HT-SELEX	6
Methyl-HT-SELEX	2

PCM	CEBPG.H12CORE.1.SM.B.pcm
PWM	CEBPG.H12CORE.1.SM.B.pwm
PFM	CEBPG.H12CORE.1.SM.B.pfm
Alignment	CEBPG.H12CORE.1.SM.B.words.tsv
Threshold to P-value map	CEBPG.H12CORE.1.SM.B.thr
Motif in other formats
JASPAR format	CEBPG.H12CORE.1.SM.B_jaspar_format.txt
MEME format	CEBPG.H12CORE.1.SM.B_meme_format.meme
Transfac format	CEBPG.H12CORE.1.SM.B_transfac_format.txt
Homer format	CEBPG.H12CORE.1.SM.B_homer_format_0.001.txt CEBPG.H12CORE.1.SM.B_homer_format_0.0005.txt CEBPG.H12CORE.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1522.5	1871.5	2524.5	4002.5
02	6667.0	482.0	2728.0	44.0
03	7.0	0.0	0.0	9914.0
04	0.0	2.0	0.0	9919.0
05	591.0	1.0	9328.0	1.0
06	1.0	9919.0	0.0	1.0
07	275.0	47.0	9563.0	36.0
08	621.0	4034.0	15.0	5251.0
09	8626.0	977.0	105.0	213.0
10	9344.0	130.0	217.0	230.0
11	749.0	3623.0	1827.0	3722.0
12	2687.25	2290.25	2373.25	2570.25

PFM

	A	C	G	T
01	0.153	0.189	0.254	0.403
02	0.672	0.049	0.275	0.004
03	0.001	0.0	0.0	0.999
04	0.0	0.0	0.0	1.0
05	0.06	0.0	0.94	0.0
06	0.0	1.0	0.0	0.0
07	0.028	0.005	0.964	0.004
08	0.063	0.407	0.002	0.529
09	0.869	0.098	0.011	0.021
10	0.942	0.013	0.022	0.023
11	0.075	0.365	0.184	0.375
12	0.271	0.231	0.239	0.259

PWM

	A	C	G	T
01	-0.487	-0.281	0.018	0.478
02	0.988	-1.634	0.095	-3.982
03	-5.587	-6.984	-6.984	1.385
04	-6.984	-6.358	-6.984	1.385
05	-1.431	-6.623	1.324	-6.623
06	-6.623	1.385	-6.984	-6.623
07	-2.192	-3.919	1.349	-4.172
08	-1.382	0.486	-4.966	0.75
09	1.246	-0.93	-3.141	-2.445
10	1.326	-2.932	-2.427	-2.369
11	-1.195	0.379	-0.305	0.406
12	0.08	-0.08	-0.044	0.036

Standard thresholds

P-value	Threshold
0.001	2.022245
0.0005	3.558425
0.0001	6.70641