CEBPE.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPE.H12RSNP.0.P.B
Gene (human)	CEBPE (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpe
Gene synonyms (mouse)	Gm294
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	vdvTKddGCAAb
GC content	46.82%
Information content (bits; total / per base)	11.353 / 0.946
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (21)	0.924	0.935	0.842	0.87	0.865	0.874	2.614	2.687	262.62	335.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.974	0.952	0.954	0.933	0.85	0.846
Overall, 6 experiments	best	0.993	0.988	0.993	0.986	0.992	0.985
Methyl HT-SELEX, 2 experiments	median	0.953	0.916	0.928	0.893	0.837	0.822
Methyl HT-SELEX, 2 experiments	best	0.966	0.938	0.963	0.934	0.933	0.904
Non-Methyl HT-SELEX, 4 experiments	median	0.984	0.971	0.965	0.951	0.872	0.876
Non-Methyl HT-SELEX, 4 experiments	best	0.993	0.988	0.993	0.986	0.992	0.985

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.916	0.797	0.906	0.645
batch 2	0.87	0.731	0.877	0.676

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.5
HGNC	HGNC:1836
MGI	MGI:103572
EntrezGene (human)	GeneID:1053 (SSTAR profile)
EntrezGene (mouse)	GeneID:110794 (SSTAR profile)
UniProt ID (human)	CEBPE_HUMAN
UniProt ID (mouse)	CEBPE_MOUSE
UniProt AC (human)	Q15744 (TFClass)
UniProt AC (mouse)	Q6PZD9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	CEBPE.H12RSNP.0.P.B.pcm
PWM	CEBPE.H12RSNP.0.P.B.pwm
PFM	CEBPE.H12RSNP.0.P.B.pfm
Alignment	CEBPE.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	CEBPE.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	CEBPE.H12RSNP.0.P.B_jaspar_format.txt
MEME format	CEBPE.H12RSNP.0.P.B_meme_format.meme
Transfac format	CEBPE.H12RSNP.0.P.B_transfac_format.txt
Homer format	CEBPE.H12RSNP.0.P.B_homer_format_0.001.txt CEBPE.H12RSNP.0.P.B_homer_format_0.0005.txt CEBPE.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	225.0	284.0	372.0	119.0
02	253.0	109.0	331.0	307.0
03	293.0	241.0	456.0	10.0
04	5.0	1.0	1.0	993.0
05	3.0	1.0	507.0	489.0
06	266.0	19.0	475.0	240.0
07	219.0	100.0	268.0	413.0
08	1.0	1.0	996.0	2.0
09	154.0	808.0	1.0	37.0
10	993.0	7.0	0.0	0.0
11	1000.0	0.0	0.0	0.0
12	31.0	368.0	272.0	329.0

PFM

	A	C	G	T
01	0.225	0.284	0.372	0.119
02	0.253	0.109	0.331	0.307
03	0.293	0.241	0.456	0.01
04	0.005	0.001	0.001	0.993
05	0.003	0.001	0.507	0.489
06	0.266	0.019	0.475	0.24
07	0.219	0.1	0.268	0.413
08	0.001	0.001	0.996	0.002
09	0.154	0.808	0.001	0.037
10	0.993	0.007	0.0	0.0
11	1.0	0.0	0.0	0.0
12	0.031	0.368	0.272	0.329

PWM

	A	C	G	T
01	-0.105	0.127	0.395	-0.735
02	0.012	-0.821	0.279	0.204
03	0.158	-0.036	0.598	-3.066
04	-3.622	-4.525	-4.525	1.374
05	-3.975	-4.525	0.704	0.668
06	0.062	-2.497	0.639	-0.041
07	-0.131	-0.906	0.069	0.499
08	-4.525	-4.525	1.377	-4.213
09	-0.48	1.168	-4.525	-1.872
10	1.374	-3.362	-4.982	-4.982
11	1.381	-4.982	-4.982	-4.982
12	-2.04	0.384	0.084	0.273

Standard thresholds

P-value	Threshold
0.001	3.73677
0.0005	5.374975
0.0001	7.8941