CEBPE.H12INVIVO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPE.H12INVIVO.1.SM.B
Gene (human)	CEBPE (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpe
Gene synonyms (mouse)	Gm294
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	13
Consensus	nvTTRCGCAAYvn
GC content	47.37%
Information content (bits; total / per base)	14.02 / 1.078
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (21)	0.901	0.918	0.816	0.843	0.805	0.813	2.383	2.474	245.854	289.276

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.997	0.995	0.967	0.963	0.873	0.87
Overall, 6 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.994	0.99	0.957	0.95	0.873	0.87
Methyl HT-SELEX, 2 experiments	best	0.996	0.992	0.987	0.982	0.952	0.942
Non-Methyl HT-SELEX, 4 experiments	median	0.998	0.997	0.971	0.969	0.88	0.89
Non-Methyl HT-SELEX, 4 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.923	0.715	0.891	0.616
batch 2	0.87	0.591	0.841	0.616

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.5
HGNC	HGNC:1836
MGI	MGI:103572
EntrezGene (human)	GeneID:1053 (SSTAR profile)
EntrezGene (mouse)	GeneID:110794 (SSTAR profile)
UniProt ID (human)	CEBPE_HUMAN
UniProt ID (mouse)	CEBPE_MOUSE
UniProt AC (human)	Q15744 (TFClass)
UniProt AC (mouse)	Q6PZD9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	CEBPE.H12INVIVO.1.SM.B.pcm
PWM	CEBPE.H12INVIVO.1.SM.B.pwm
PFM	CEBPE.H12INVIVO.1.SM.B.pfm
Alignment	CEBPE.H12INVIVO.1.SM.B.words.tsv
Threshold to P-value map	CEBPE.H12INVIVO.1.SM.B.thr
Motif in other formats
JASPAR format	CEBPE.H12INVIVO.1.SM.B_jaspar_format.txt
MEME format	CEBPE.H12INVIVO.1.SM.B_meme_format.meme
Transfac format	CEBPE.H12INVIVO.1.SM.B_transfac_format.txt
Homer format	CEBPE.H12INVIVO.1.SM.B_homer_format_0.001.txt CEBPE.H12INVIVO.1.SM.B_homer_format_0.0005.txt CEBPE.H12INVIVO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2225.25	2976.25	1877.25	1921.25
02	3486.0	1658.0	3373.0	483.0
03	260.0	300.0	122.0	8318.0
04	212.0	190.0	1031.0	7567.0
05	3965.0	38.0	4128.0	869.0
06	16.0	8380.0	25.0	579.0
07	0.0	0.0	8999.0	1.0
08	1.0	8791.0	0.0	208.0
09	9000.0	0.0	0.0	0.0
10	9000.0	0.0	0.0	0.0
11	12.0	3282.0	365.0	5341.0
12	3086.25	3328.25	1685.25	900.25
13	1954.0	2793.0	2076.0	2177.0

PFM

	A	C	G	T
01	0.247	0.331	0.209	0.213
02	0.387	0.184	0.375	0.054
03	0.029	0.033	0.014	0.924
04	0.024	0.021	0.115	0.841
05	0.441	0.004	0.459	0.097
06	0.002	0.931	0.003	0.064
07	0.0	0.0	1.0	0.0
08	0.0	0.977	0.0	0.023
09	1.0	0.0	0.0	0.0
10	1.0	0.0	0.0	0.0
11	0.001	0.365	0.041	0.593
12	0.343	0.37	0.187	0.1
13	0.217	0.31	0.231	0.242

PWM

	A	C	G	T
01	-0.011	0.279	-0.181	-0.158
02	0.437	-0.305	0.405	-1.535
03	-2.15	-2.008	-2.897	1.307
04	-2.352	-2.461	-0.779	1.212
05	0.566	-4.024	0.606	-0.95
06	-4.814	1.314	-4.414	-1.354
07	-6.897	-6.897	1.385	-6.533
08	-6.533	1.362	-6.897	-2.371
09	1.386	-6.897	-6.897	-6.897
10	1.386	-6.897	-6.897	-6.897
11	-5.061	0.377	-1.814	0.864
12	0.316	0.391	-0.289	-0.914
13	-0.141	0.216	-0.08	-0.033

Standard thresholds

P-value	Threshold
0.001	2.02681
0.0005	3.63891
0.0001	6.85812