CEBPE.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPE.H12INVIVO.0.P.B
Gene (human)	CEBPE (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpe
Gene synonyms (mouse)	Gm294
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	dvTKddGCAAb
GC content	44.37%
Information content (bits; total / per base)	10.836 / 0.985
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (21)	0.928	0.938	0.849	0.868	0.865	0.874	2.593	2.694	274.027	323.481

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.98	0.965	0.96	0.943	0.858	0.857
Overall, 6 experiments	best	0.996	0.994	0.995	0.991	0.993	0.989
Methyl HT-SELEX, 2 experiments	median	0.961	0.933	0.933	0.904	0.844	0.834
Methyl HT-SELEX, 2 experiments	best	0.975	0.956	0.97	0.947	0.945	0.921
Non-Methyl HT-SELEX, 4 experiments	median	0.987	0.977	0.967	0.957	0.874	0.88
Non-Methyl HT-SELEX, 4 experiments	best	0.996	0.994	0.995	0.991	0.993	0.989

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.913	0.79	0.906	0.644
batch 2	0.878	0.724	0.873	0.662

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.5
HGNC	HGNC:1836
MGI	MGI:103572
EntrezGene (human)	GeneID:1053 (SSTAR profile)
EntrezGene (mouse)	GeneID:110794 (SSTAR profile)
UniProt ID (human)	CEBPE_HUMAN
UniProt ID (mouse)	CEBPE_MOUSE
UniProt AC (human)	Q15744 (TFClass)
UniProt AC (mouse)	Q6PZD9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	CEBPE.H12INVIVO.0.P.B.pcm
PWM	CEBPE.H12INVIVO.0.P.B.pwm
PFM	CEBPE.H12INVIVO.0.P.B.pfm
Alignment	CEBPE.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	CEBPE.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	CEBPE.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	CEBPE.H12INVIVO.0.P.B_meme_format.meme
Transfac format	CEBPE.H12INVIVO.0.P.B_transfac_format.txt
Homer format	CEBPE.H12INVIVO.0.P.B_homer_format_0.001.txt CEBPE.H12INVIVO.0.P.B_homer_format_0.0005.txt CEBPE.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	225.0	126.0	335.0	314.0
02	313.0	230.0	427.0	30.0
03	5.0	10.0	2.0	983.0
04	2.0	1.0	478.0	519.0
05	265.0	23.0	453.0	259.0
06	186.0	105.0	273.0	436.0
07	0.0	3.0	994.0	3.0
08	162.0	792.0	3.0	43.0
09	974.0	26.0	0.0	0.0
10	994.0	1.0	5.0	0.0
11	29.0	354.0	240.0	377.0

PFM

	A	C	G	T
01	0.225	0.126	0.335	0.314
02	0.313	0.23	0.427	0.03
03	0.005	0.01	0.002	0.983
04	0.002	0.001	0.478	0.519
05	0.265	0.023	0.453	0.259
06	0.186	0.105	0.273	0.436
07	0.0	0.003	0.994	0.003
08	0.162	0.792	0.003	0.043
09	0.974	0.026	0.0	0.0
10	0.994	0.001	0.005	0.0
11	0.029	0.354	0.24	0.377

PWM

	A	C	G	T
01	-0.105	-0.678	0.291	0.227
02	0.223	-0.083	0.532	-2.071
03	-3.622	-3.066	-4.213	1.364
04	-4.213	-4.525	0.645	0.727
05	0.058	-2.32	0.591	0.035
06	-0.293	-0.858	0.087	0.553
07	-4.982	-3.975	1.375	-3.975
08	-0.43	1.148	-3.975	-1.728
09	1.355	-2.206	-4.982	-4.982
10	1.375	-4.525	-3.622	-4.982
11	-2.103	0.346	-0.041	0.408

Standard thresholds

P-value	Threshold
0.001	4.22336
0.0005	5.600295
0.0001	7.86655