CEBPE.H12INVITRO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPE.H12INVITRO.1.SM.B
Gene (human)	CEBPE (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpe
Gene synonyms (mouse)	Gm294
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	vTTRCGCAAYn
GC content	45.79%
Information content (bits; total / per base)	13.006 / 1.182
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9955

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (21)	0.899	0.914	0.803	0.831	0.789	0.796	2.282	2.364	258.538	313.409

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.997	0.996	0.971	0.968	0.879	0.879
Overall, 6 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.994	0.991	0.96	0.954	0.879	0.878
Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.991	0.988	0.964	0.956
Non-Methyl HT-SELEX, 4 experiments	median	0.998	0.997	0.973	0.971	0.881	0.891
Non-Methyl HT-SELEX, 4 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.909	0.707	0.895	0.606
batch 2	0.862	0.586	0.846	0.601

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.5
HGNC	HGNC:1836
MGI	MGI:103572
EntrezGene (human)	GeneID:1053 (SSTAR profile)
EntrezGene (mouse)	GeneID:110794 (SSTAR profile)
UniProt ID (human)	CEBPE_HUMAN
UniProt ID (mouse)	CEBPE_MOUSE
UniProt AC (human)	Q15744 (TFClass)
UniProt AC (mouse)	Q6PZD9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	CEBPE.H12INVITRO.1.SM.B.pcm
PWM	CEBPE.H12INVITRO.1.SM.B.pwm
PFM	CEBPE.H12INVITRO.1.SM.B.pfm
Alignment	CEBPE.H12INVITRO.1.SM.B.words.tsv
Threshold to P-value map	CEBPE.H12INVITRO.1.SM.B.thr
Motif in other formats
JASPAR format	CEBPE.H12INVITRO.1.SM.B_jaspar_format.txt
MEME format	CEBPE.H12INVITRO.1.SM.B_meme_format.meme
Transfac format	CEBPE.H12INVITRO.1.SM.B_transfac_format.txt
Homer format	CEBPE.H12INVITRO.1.SM.B_homer_format_0.001.txt CEBPE.H12INVITRO.1.SM.B_homer_format_0.0005.txt CEBPE.H12INVITRO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3326.5	2832.5	3052.5	743.5
02	257.0	347.0	197.0	9154.0
03	201.0	287.0	1709.0	7758.0
04	4379.0	58.0	3425.0	2093.0
05	11.0	9396.0	5.0	543.0
06	6.0	1.0	9946.0	2.0
07	4.0	9217.0	2.0	732.0
08	9949.0	0.0	3.0	3.0
09	9929.0	4.0	21.0	1.0
10	11.0	3187.0	1184.0	5573.0
11	3204.0	2955.0	2313.0	1483.0

PFM

	A	C	G	T
01	0.334	0.285	0.307	0.075
02	0.026	0.035	0.02	0.92
03	0.02	0.029	0.172	0.779
04	0.44	0.006	0.344	0.21
05	0.001	0.944	0.001	0.055
06	0.001	0.0	0.999	0.0
07	0.0	0.926	0.0	0.074
08	0.999	0.0	0.0	0.0
09	0.997	0.0	0.002	0.0
10	0.001	0.32	0.119	0.56
11	0.322	0.297	0.232	0.149

PWM

	A	C	G	T
01	0.29	0.129	0.204	-1.206
02	-2.262	-1.965	-2.526	1.302
03	-2.506	-2.153	-0.375	1.136
04	0.565	-3.721	0.319	-0.173
05	-5.233	1.328	-5.832	-1.519
06	-5.704	-6.626	1.385	-6.362
07	-5.98	1.309	-6.362	-1.222
08	1.385	-6.987	-6.152	-6.152
09	1.383	-5.98	-4.672	-6.626
10	-5.233	0.247	-0.742	0.806
11	0.252	0.172	-0.073	-0.517

Standard thresholds

P-value	Threshold
0.001	2.849405
0.0005	4.285075
0.0001	7.15908