CEBPE.H12CORE.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPE.H12CORE.1.SM.B
Gene (human)	CEBPE (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpe
Gene synonyms (mouse)	Gm294
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	13
Consensus	nvTTRCGCAATvn
GC content	47.79%
Information content (bits; total / per base)	16.437 / 1.264
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	6030

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (21)	0.692	0.703	0.646	0.665	0.787	0.802	2.313	2.434	174.208	203.398

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.997	0.994	0.967	0.964	0.866	0.868
Overall, 6 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.993	0.99	0.955	0.948	0.866	0.865
Methyl HT-SELEX, 2 experiments	best	0.996	0.992	0.987	0.981	0.95	0.939
Non-Methyl HT-SELEX, 4 experiments	median	0.998	0.997	0.972	0.97	0.878	0.889
Non-Methyl HT-SELEX, 4 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.93	0.796	0.914	0.6
batch 2	0.882	0.68	0.876	0.641

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.5
HGNC	HGNC:1836
MGI	MGI:103572
EntrezGene (human)	GeneID:1053 (SSTAR profile)
EntrezGene (mouse)	GeneID:110794 (SSTAR profile)
UniProt ID (human)	CEBPE_HUMAN
UniProt ID (mouse)	CEBPE_MOUSE
UniProt AC (human)	Q15744 (TFClass)
UniProt AC (mouse)	Q6PZD9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	CEBPE.H12CORE.1.SM.B.pcm
PWM	CEBPE.H12CORE.1.SM.B.pwm
PFM	CEBPE.H12CORE.1.SM.B.pfm
Alignment	CEBPE.H12CORE.1.SM.B.words.tsv
Threshold to P-value map	CEBPE.H12CORE.1.SM.B.thr
Motif in other formats
JASPAR format	CEBPE.H12CORE.1.SM.B_jaspar_format.txt
MEME format	CEBPE.H12CORE.1.SM.B_meme_format.meme
Transfac format	CEBPE.H12CORE.1.SM.B_transfac_format.txt
Homer format	CEBPE.H12CORE.1.SM.B_homer_format_0.001.txt CEBPE.H12CORE.1.SM.B_homer_format_0.0005.txt CEBPE.H12CORE.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1477.5	2142.5	1156.5	1253.5
02	2344.0	1112.0	2443.0	131.0
03	0.0	0.0	0.0	6030.0
04	0.0	0.0	106.0	5924.0
05	2546.0	0.0	3388.0	96.0
06	0.0	6024.0	0.0	6.0
07	0.0	0.0	6030.0	0.0
08	0.0	6030.0	0.0	0.0
09	6030.0	0.0	0.0	0.0
10	6030.0	0.0	0.0	0.0
11	0.0	2347.0	2.0	3681.0
12	2111.25	2349.25	1045.25	524.25
13	1295.25	1942.25	1347.25	1445.25

PFM

	A	C	G	T
01	0.245	0.355	0.192	0.208
02	0.389	0.184	0.405	0.022
03	0.0	0.0	0.0	1.0
04	0.0	0.0	0.018	0.982
05	0.422	0.0	0.562	0.016
06	0.0	0.999	0.0	0.001
07	0.0	0.0	1.0	0.0
08	0.0	1.0	0.0	0.0
09	1.0	0.0	0.0	0.0
10	1.0	0.0	0.0	0.0
11	0.0	0.389	0.0	0.61
12	0.35	0.39	0.173	0.087
13	0.215	0.322	0.223	0.24

PWM

	A	C	G	T
01	-0.02	0.351	-0.265	-0.184
02	0.441	-0.304	0.482	-2.428
03	-6.542	-6.542	-6.542	1.385
04	-6.542	-6.542	-2.636	1.367
05	0.523	-6.542	0.809	-2.733
06	-6.542	1.384	-6.542	-5.218
07	-6.542	-6.542	1.385	-6.542
08	-6.542	1.385	-6.542	-6.542
09	1.385	-6.542	-6.542	-6.542
10	1.385	-6.542	-6.542	-6.542
11	-6.542	0.442	-5.89	0.892
12	0.336	0.443	-0.366	-1.054
13	-0.152	0.253	-0.112	-0.042

Standard thresholds

P-value	Threshold
0.001	-3.29403
0.0005	-0.329815
0.0001	3.840345