Motif | CEBPB.H12INVIVO.1.SM.B |
Gene (human) | CEBPB (GeneCards) |
Gene synonyms (human) | TCF5 |
Gene (mouse) | Cebpb |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | CEBPB.H12INVIVO.1.SM.B |
Gene (human) | CEBPB (GeneCards) |
Gene synonyms (human) | TCF5 |
Gene (mouse) | Cebpb |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 13 |
Consensus | nvTTRCGCAAYvn |
GC content | 47.84% |
Information content (bits; total / per base) | 14.999 / 1.154 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9724 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 74 (475) | 0.947 | 0.982 | 0.888 | 0.977 | 0.901 | 0.968 | 3.369 | 5.805 | 454.26 | 957.328 |
Mouse | 112 (694) | 0.959 | 0.985 | 0.918 | 0.981 | 0.891 | 0.962 | 3.28 | 4.857 | 449.512 | 901.387 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 10 experiments | median | 0.998 | 0.996 | 0.995 | 0.993 | 0.971 | 0.964 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | |
Methyl HT-SELEX, 2 experiments | median | 0.997 | 0.994 | 0.993 | 0.989 | 0.975 | 0.968 |
best | 0.997 | 0.994 | 0.994 | 0.99 | 0.979 | 0.971 | |
Non-Methyl HT-SELEX, 8 experiments | median | 0.999 | 0.998 | 0.997 | 0.996 | 0.968 | 0.963 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 12.626 | 155.685 | 0.449 | 0.414 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.944 | 0.831 | 0.938 | 0.638 |
batch 2 | 0.729 | 0.225 | 0.709 | 0.433 |
TF superclass | Basic domains {1} (TFClass) |
TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
TF family | C/EBP-related {1.1.8} (TFClass) |
TF subfamily | CEBP {1.1.8.1} (TFClass) |
TFClass ID | TFClass: 1.1.8.1.2 |
HGNC | HGNC:1834 |
MGI | MGI:88373 |
EntrezGene (human) | GeneID:1051 (SSTAR profile) |
EntrezGene (mouse) | GeneID:12608 (SSTAR profile) |
UniProt ID (human) | CEBPB_HUMAN |
UniProt ID (mouse) | CEBPB_MOUSE |
UniProt AC (human) | P17676 (TFClass) |
UniProt AC (mouse) | P28033 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 74 human, 112 mouse |
HT-SELEX | 8 |
Methyl-HT-SELEX | 2 |
PCM | CEBPB.H12INVIVO.1.SM.B.pcm |
PWM | CEBPB.H12INVIVO.1.SM.B.pwm |
PFM | CEBPB.H12INVIVO.1.SM.B.pfm |
Alignment | CEBPB.H12INVIVO.1.SM.B.words.tsv |
Threshold to P-value map | CEBPB.H12INVIVO.1.SM.B.thr |
Motif in other formats | |
JASPAR format | CEBPB.H12INVIVO.1.SM.B_jaspar_format.txt |
MEME format | CEBPB.H12INVIVO.1.SM.B_meme_format.meme |
Transfac format | CEBPB.H12INVIVO.1.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2172.75 | 3464.75 | 2025.75 | 2060.75 |
02 | 4250.5 | 2283.5 | 2700.5 | 489.5 |
03 | 59.0 | 51.0 | 30.0 | 9584.0 |
04 | 31.0 | 31.0 | 526.0 | 9136.0 |
05 | 4310.0 | 4.0 | 4970.0 | 440.0 |
06 | 6.0 | 9451.0 | 2.0 | 265.0 |
07 | 4.0 | 7.0 | 9712.0 | 1.0 |
08 | 16.0 | 9236.0 | 0.0 | 472.0 |
09 | 9723.0 | 1.0 | 0.0 | 0.0 |
10 | 9723.0 | 0.0 | 0.0 | 1.0 |
11 | 3.0 | 4728.0 | 475.0 | 4518.0 |
12 | 3290.75 | 3555.75 | 1842.75 | 1034.75 |
13 | 2200.5 | 3149.5 | 2227.5 | 2146.5 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.223 | 0.356 | 0.208 | 0.212 |
02 | 0.437 | 0.235 | 0.278 | 0.05 |
03 | 0.006 | 0.005 | 0.003 | 0.986 |
04 | 0.003 | 0.003 | 0.054 | 0.94 |
05 | 0.443 | 0.0 | 0.511 | 0.045 |
06 | 0.001 | 0.972 | 0.0 | 0.027 |
07 | 0.0 | 0.001 | 0.999 | 0.0 |
08 | 0.002 | 0.95 | 0.0 | 0.049 |
09 | 1.0 | 0.0 | 0.0 | 0.0 |
10 | 1.0 | 0.0 | 0.0 | 0.0 |
11 | 0.0 | 0.486 | 0.049 | 0.465 |
12 | 0.338 | 0.366 | 0.19 | 0.106 |
13 | 0.226 | 0.324 | 0.229 | 0.221 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.112 | 0.354 | -0.182 | -0.165 |
02 | 0.558 | -0.063 | 0.105 | -1.599 |
03 | -3.681 | -3.821 | -4.322 | 1.371 |
04 | -4.292 | -4.292 | -1.527 | 1.323 |
05 | 0.572 | -5.957 | 0.715 | -1.705 |
06 | -5.681 | 1.357 | -6.339 | -2.209 |
07 | -5.957 | -5.567 | 1.384 | -6.604 |
08 | -4.89 | 1.334 | -6.966 | -1.635 |
09 | 1.385 | -6.604 | -6.966 | -6.966 |
10 | 1.385 | -6.966 | -6.966 | -6.604 |
11 | -6.13 | 0.665 | -1.629 | 0.619 |
12 | 0.303 | 0.38 | -0.277 | -0.853 |
13 | -0.1 | 0.259 | -0.087 | -0.124 |
P-value | Threshold |
---|---|
0.001 | 0.686265 |
0.0005 | 2.540215 |
0.0001 | 5.84857 |