MotifCEBPB.H12INVIVO.1.SM.B
Gene (human)CEBPB
(GeneCards)
Gene synonyms (human)TCF5
Gene (mouse)Cebpb
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length13
ConsensusnvTTRCGCAAYvn
GC content47.84%
Information content (bits; total / per base)14.999 / 1.154
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9724

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 74 (475) 0.947 0.982 0.888 0.977 0.901 0.968 3.369 5.805 454.26 957.328
Mouse 112 (694) 0.959 0.985 0.918 0.981 0.891 0.962 3.28 4.857 449.512 901.387

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.998 0.996 0.995 0.993 0.971 0.964
best 1.0 1.0 1.0 1.0 0.999 0.999
Methyl HT-SELEX, 2 experiments median 0.997 0.994 0.993 0.989 0.975 0.968
best 0.997 0.994 0.994 0.99 0.979 0.971
Non-Methyl HT-SELEX, 8 experiments median 0.999 0.998 0.997 0.996 0.968 0.963
best 1.0 1.0 1.0 1.0 0.999 0.999

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 12.626 155.685 0.449 0.414

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.944 0.831 0.938 0.638
batch 2 0.729 0.225 0.709 0.433
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyC/EBP-related {1.1.8} (TFClass)
TF subfamilyCEBP {1.1.8.1} (TFClass)
TFClass IDTFClass: 1.1.8.1.2
HGNCHGNC:1834
MGIMGI:88373
EntrezGene (human)GeneID:1051
(SSTAR profile)
EntrezGene (mouse)GeneID:12608
(SSTAR profile)
UniProt ID (human)CEBPB_HUMAN
UniProt ID (mouse)CEBPB_MOUSE
UniProt AC (human)P17676
(TFClass)
UniProt AC (mouse)P28033
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 74 human, 112 mouse
HT-SELEX 8
Methyl-HT-SELEX 2
PCM
ACGT
012172.753464.752025.752060.75
024250.52283.52700.5489.5
0359.051.030.09584.0
0431.031.0526.09136.0
054310.04.04970.0440.0
066.09451.02.0265.0
074.07.09712.01.0
0816.09236.00.0472.0
099723.01.00.00.0
109723.00.00.01.0
113.04728.0475.04518.0
123290.753555.751842.751034.75
132200.53149.52227.52146.5
PFM
ACGT
010.2230.3560.2080.212
020.4370.2350.2780.05
030.0060.0050.0030.986
040.0030.0030.0540.94
050.4430.00.5110.045
060.0010.9720.00.027
070.00.0010.9990.0
080.0020.950.00.049
091.00.00.00.0
101.00.00.00.0
110.00.4860.0490.465
120.3380.3660.190.106
130.2260.3240.2290.221
PWM
ACGT
01-0.1120.354-0.182-0.165
020.558-0.0630.105-1.599
03-3.681-3.821-4.3221.371
04-4.292-4.292-1.5271.323
050.572-5.9570.715-1.705
06-5.6811.357-6.339-2.209
07-5.957-5.5671.384-6.604
08-4.891.334-6.966-1.635
091.385-6.604-6.966-6.966
101.385-6.966-6.966-6.604
11-6.130.665-1.6290.619
120.3030.38-0.277-0.853
13-0.10.259-0.087-0.124
Standard thresholds
P-value Threshold
0.001 0.686265
0.0005 2.540215
0.0001 5.84857