CEBPB.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPB.H12INVIVO.0.P.B
Gene (human)	CEBPB (GeneCards)
Gene synonyms (human)	TCF5
Gene (mouse)	Cebpb
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	dRTTRhGCAAYv
GC content	42.06%
Information content (bits; total / per base)	11.799 / 0.983
Data sources	ChIP-Seq
Aligned words	992

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	74 (475)	0.957	0.983	0.91	0.965	0.94	0.976	3.858	4.862	518.42	1072.602
Mouse	112 (694)	0.971	0.993	0.936	0.985	0.932	0.969	3.701	4.611	516.306	1035.337

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	0.996	0.994	0.994	0.99	0.974	0.964
Overall, 10 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.994	0.991	0.99	0.984	0.972	0.963
Methyl HT-SELEX, 2 experiments	best	0.995	0.991	0.991	0.985	0.976	0.966
Non-Methyl HT-SELEX, 8 experiments	median	0.998	0.997	0.997	0.995	0.975	0.969
Non-Methyl HT-SELEX, 8 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.695	77.353	0.332	0.333

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.891	0.794	0.918	0.673
batch 2	0.759	0.285	0.697	0.448

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.2
HGNC	HGNC:1834
MGI	MGI:88373
EntrezGene (human)	GeneID:1051 (SSTAR profile)
EntrezGene (mouse)	GeneID:12608 (SSTAR profile)
UniProt ID (human)	CEBPB_HUMAN
UniProt ID (mouse)	CEBPB_MOUSE
UniProt AC (human)	P17676 (TFClass)
UniProt AC (mouse)	P28033 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	74 human, 112 mouse
HT-SELEX	8
Methyl-HT-SELEX	2

PCM	CEBPB.H12INVIVO.0.P.B.pcm
PWM	CEBPB.H12INVIVO.0.P.B.pwm
PFM	CEBPB.H12INVIVO.0.P.B.pfm
Alignment	CEBPB.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	CEBPB.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	CEBPB.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	CEBPB.H12INVIVO.0.P.B_meme_format.meme
Transfac format	CEBPB.H12INVIVO.0.P.B_transfac_format.txt
Homer format	CEBPB.H12INVIVO.0.P.B_homer_format_0.001.txt CEBPB.H12INVIVO.0.P.B_homer_format_0.0005.txt CEBPB.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	197.0	125.0	326.0	344.0
02	421.0	159.0	399.0	13.0
03	7.0	3.0	6.0	976.0
04	3.0	7.0	234.0	748.0
05	269.0	3.0	524.0	196.0
06	135.0	347.0	71.0	439.0
07	2.0	4.0	983.0	3.0
08	80.0	865.0	5.0	42.0
09	974.0	10.0	3.0	5.0
10	969.0	5.0	11.0	7.0
11	21.0	239.0	155.0	577.0
12	329.0	339.0	184.0	140.0

PFM

	A	C	G	T
01	0.199	0.126	0.329	0.347
02	0.424	0.16	0.402	0.013
03	0.007	0.003	0.006	0.984
04	0.003	0.007	0.236	0.754
05	0.271	0.003	0.528	0.198
06	0.136	0.35	0.072	0.443
07	0.002	0.004	0.991	0.003
08	0.081	0.872	0.005	0.042
09	0.982	0.01	0.003	0.005
10	0.977	0.005	0.011	0.007
11	0.021	0.241	0.156	0.582
12	0.332	0.342	0.185	0.141

PWM

	A	C	G	T
01	-0.228	-0.678	0.272	0.325
02	0.526	-0.441	0.473	-2.831
03	-3.354	-3.968	-3.476	1.365
04	-3.968	-3.354	-0.058	1.099
05	0.081	-3.968	0.744	-0.233
06	-0.602	0.334	-1.234	0.568
07	-4.205	-3.776	1.372	-3.968
08	-1.117	1.244	-3.615	-1.742
09	1.363	-3.059	-3.968	-3.615
10	1.358	-3.615	-2.977	-3.354
11	-2.397	-0.037	-0.466	0.84
12	0.281	0.311	-0.296	-0.566

Standard thresholds

P-value	Threshold
0.001	4.01436
0.0005	5.044085
0.0001	7.530695