CEBPB.H12CORE.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPB.H12CORE.1.SM.B
Gene (human)	CEBPB (GeneCards)
Gene synonyms (human)	TCF5
Gene (mouse)	Cebpb
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	13
Consensus	nvTTRCGCAAYvn
GC content	47.84%
Information content (bits; total / per base)	14.999 / 1.154
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9724

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	74 (475)	0.947	0.982	0.888	0.977	0.901	0.968	3.369	5.805	454.26	957.328
Mouse	112 (694)	0.959	0.985	0.918	0.981	0.891	0.962	3.28	4.857	449.512	901.387

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	0.998	0.996	0.995	0.993	0.971	0.964
Overall, 10 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.997	0.994	0.993	0.989	0.975	0.968
Methyl HT-SELEX, 2 experiments	best	0.997	0.994	0.994	0.99	0.979	0.971
Non-Methyl HT-SELEX, 8 experiments	median	0.999	0.998	0.997	0.996	0.968	0.963
Non-Methyl HT-SELEX, 8 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	12.626	155.685	0.449	0.414

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.944	0.831	0.938	0.638
batch 2	0.729	0.225	0.709	0.433

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.2
HGNC	HGNC:1834
MGI	MGI:88373
EntrezGene (human)	GeneID:1051 (SSTAR profile)
EntrezGene (mouse)	GeneID:12608 (SSTAR profile)
UniProt ID (human)	CEBPB_HUMAN
UniProt ID (mouse)	CEBPB_MOUSE
UniProt AC (human)	P17676 (TFClass)
UniProt AC (mouse)	P28033 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	74 human, 112 mouse
HT-SELEX	8
Methyl-HT-SELEX	2

PCM	CEBPB.H12CORE.1.SM.B.pcm
PWM	CEBPB.H12CORE.1.SM.B.pwm
PFM	CEBPB.H12CORE.1.SM.B.pfm
Alignment	CEBPB.H12CORE.1.SM.B.words.tsv
Threshold to P-value map	CEBPB.H12CORE.1.SM.B.thr
Motif in other formats
JASPAR format	CEBPB.H12CORE.1.SM.B_jaspar_format.txt
MEME format	CEBPB.H12CORE.1.SM.B_meme_format.meme
Transfac format	CEBPB.H12CORE.1.SM.B_transfac_format.txt
Homer format	CEBPB.H12CORE.1.SM.B_homer_format_0.001.txt CEBPB.H12CORE.1.SM.B_homer_format_0.0005.txt CEBPB.H12CORE.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2172.75	3464.75	2025.75	2060.75
02	4250.5	2283.5	2700.5	489.5
03	59.0	51.0	30.0	9584.0
04	31.0	31.0	526.0	9136.0
05	4310.0	4.0	4970.0	440.0
06	6.0	9451.0	2.0	265.0
07	4.0	7.0	9712.0	1.0
08	16.0	9236.0	0.0	472.0
09	9723.0	1.0	0.0	0.0
10	9723.0	0.0	0.0	1.0
11	3.0	4728.0	475.0	4518.0
12	3290.75	3555.75	1842.75	1034.75
13	2200.5	3149.5	2227.5	2146.5

PFM

	A	C	G	T
01	0.223	0.356	0.208	0.212
02	0.437	0.235	0.278	0.05
03	0.006	0.005	0.003	0.986
04	0.003	0.003	0.054	0.94
05	0.443	0.0	0.511	0.045
06	0.001	0.972	0.0	0.027
07	0.0	0.001	0.999	0.0
08	0.002	0.95	0.0	0.049
09	1.0	0.0	0.0	0.0
10	1.0	0.0	0.0	0.0
11	0.0	0.486	0.049	0.465
12	0.338	0.366	0.19	0.106
13	0.226	0.324	0.229	0.221

PWM

	A	C	G	T
01	-0.112	0.354	-0.182	-0.165
02	0.558	-0.063	0.105	-1.599
03	-3.681	-3.821	-4.322	1.371
04	-4.292	-4.292	-1.527	1.323
05	0.572	-5.957	0.715	-1.705
06	-5.681	1.357	-6.339	-2.209
07	-5.957	-5.567	1.384	-6.604
08	-4.89	1.334	-6.966	-1.635
09	1.385	-6.604	-6.966	-6.966
10	1.385	-6.966	-6.966	-6.604
11	-6.13	0.665	-1.629	0.619
12	0.303	0.38	-0.277	-0.853
13	-0.1	0.259	-0.087	-0.124

Standard thresholds

P-value	Threshold
0.001	0.686265
0.0005	2.540215
0.0001	5.84857