CEBPB.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPB.H12CORE.0.P.B
Gene (human)	CEBPB (GeneCards)
Gene synonyms (human)	TCF5
Gene (mouse)	Cebpb
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	dRTTRYGCAAY
GC content	41.98%
Information content (bits; total / per base)	12.402 / 1.127
Data sources	ChIP-Seq
Aligned words	963

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	74 (475)	0.957	0.983	0.904	0.963	0.939	0.98	3.813	5.335	521.301	1085.108
Mouse	112 (694)	0.972	0.993	0.938	0.987	0.93	0.971	3.626	4.704	522.113	1036.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	0.997	0.995	0.994	0.991	0.976	0.967
Overall, 10 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.995	0.992	0.991	0.986	0.975	0.967
Methyl HT-SELEX, 2 experiments	best	0.996	0.992	0.992	0.987	0.979	0.969
Non-Methyl HT-SELEX, 8 experiments	median	0.998	0.997	0.997	0.995	0.977	0.971
Non-Methyl HT-SELEX, 8 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	17.599	187.56	0.372	0.386

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.904	0.812	0.94	0.694
batch 2	0.743	0.304	0.701	0.443

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.2
HGNC	HGNC:1834
MGI	MGI:88373
EntrezGene (human)	GeneID:1051 (SSTAR profile)
EntrezGene (mouse)	GeneID:12608 (SSTAR profile)
UniProt ID (human)	CEBPB_HUMAN
UniProt ID (mouse)	CEBPB_MOUSE
UniProt AC (human)	P17676 (TFClass)
UniProt AC (mouse)	P28033 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	74 human, 112 mouse
HT-SELEX	8
Methyl-HT-SELEX	2

PCM	CEBPB.H12CORE.0.P.B.pcm
PWM	CEBPB.H12CORE.0.P.B.pwm
PFM	CEBPB.H12CORE.0.P.B.pfm
Alignment	CEBPB.H12CORE.0.P.B.words.tsv
Threshold to P-value map	CEBPB.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	CEBPB.H12CORE.0.P.B_jaspar_format.txt
MEME format	CEBPB.H12CORE.0.P.B_meme_format.meme
Transfac format	CEBPB.H12CORE.0.P.B_transfac_format.txt
Homer format	CEBPB.H12CORE.0.P.B_homer_format_0.001.txt CEBPB.H12CORE.0.P.B_homer_format_0.0005.txt CEBPB.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	232.0	65.0	352.0	314.0
02	403.0	106.0	446.0	8.0
03	4.0	5.0	4.0	950.0
04	3.0	5.0	267.0	688.0
05	319.0	1.0	478.0	165.0
06	54.0	485.0	30.0	394.0
07	5.0	8.0	943.0	7.0
08	61.0	870.0	2.0	30.0
09	952.0	7.0	1.0	3.0
10	951.0	4.0	4.0	4.0
11	19.0	236.0	128.0	580.0

PFM

	A	C	G	T
01	0.241	0.067	0.366	0.326
02	0.418	0.11	0.463	0.008
03	0.004	0.005	0.004	0.987
04	0.003	0.005	0.277	0.714
05	0.331	0.001	0.496	0.171
06	0.056	0.504	0.031	0.409
07	0.005	0.008	0.979	0.007
08	0.063	0.903	0.002	0.031
09	0.989	0.007	0.001	0.003
10	0.988	0.004	0.004	0.004
11	0.02	0.245	0.133	0.602

PWM

	A	C	G	T
01	-0.037	-1.29	0.378	0.264
02	0.512	-0.811	0.613	-3.217
03	-3.747	-3.586	-3.747	1.367
04	-3.94	-3.586	0.103	1.045
05	0.28	-4.491	0.682	-0.375
06	-1.471	0.697	-2.034	0.49
07	-3.586	-3.217	1.36	-3.326
08	-1.352	1.28	-4.178	-2.034
09	1.369	-3.326	-4.491	-3.94
10	1.368	-3.747	-3.747	-3.747
11	-2.46	-0.02	-0.626	0.875

Standard thresholds

P-value	Threshold
0.001	3.777865
0.0005	4.83456
0.0001	7.30382