MotifCEBPB.H12CORE.0.P.B
Gene (human)CEBPB
(GeneCards)
Gene synonyms (human)TCF5
Gene (mouse)Cebpb
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusdRTTRYGCAAY
GC content41.98%
Information content (bits; total / per base)12.402 / 1.127
Data sourcesChIP-Seq
Aligned words963

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 74 (475) 0.957 0.983 0.904 0.963 0.939 0.98 3.813 5.335 521.301 1085.108
Mouse 112 (694) 0.972 0.993 0.938 0.987 0.93 0.971 3.626 4.704 522.113 1036.699

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.997 0.995 0.994 0.991 0.976 0.967
best 1.0 1.0 1.0 1.0 0.999 0.999
Methyl HT-SELEX, 2 experiments median 0.995 0.992 0.991 0.986 0.975 0.967
best 0.996 0.992 0.992 0.987 0.979 0.969
Non-Methyl HT-SELEX, 8 experiments median 0.998 0.997 0.997 0.995 0.977 0.971
best 1.0 1.0 1.0 1.0 0.999 0.999

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 17.599 187.56 0.372 0.386

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.904 0.812 0.94 0.694
batch 2 0.743 0.304 0.701 0.443
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyC/EBP-related {1.1.8} (TFClass)
TF subfamilyCEBP {1.1.8.1} (TFClass)
TFClass IDTFClass: 1.1.8.1.2
HGNCHGNC:1834
MGIMGI:88373
EntrezGene (human)GeneID:1051
(SSTAR profile)
EntrezGene (mouse)GeneID:12608
(SSTAR profile)
UniProt ID (human)CEBPB_HUMAN
UniProt ID (mouse)CEBPB_MOUSE
UniProt AC (human)P17676
(TFClass)
UniProt AC (mouse)P28033
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 74 human, 112 mouse
HT-SELEX 8
Methyl-HT-SELEX 2
PCM
ACGT
01232.065.0352.0314.0
02403.0106.0446.08.0
034.05.04.0950.0
043.05.0267.0688.0
05319.01.0478.0165.0
0654.0485.030.0394.0
075.08.0943.07.0
0861.0870.02.030.0
09952.07.01.03.0
10951.04.04.04.0
1119.0236.0128.0580.0
PFM
ACGT
010.2410.0670.3660.326
020.4180.110.4630.008
030.0040.0050.0040.987
040.0030.0050.2770.714
050.3310.0010.4960.171
060.0560.5040.0310.409
070.0050.0080.9790.007
080.0630.9030.0020.031
090.9890.0070.0010.003
100.9880.0040.0040.004
110.020.2450.1330.602
PWM
ACGT
01-0.037-1.290.3780.264
020.512-0.8110.613-3.217
03-3.747-3.586-3.7471.367
04-3.94-3.5860.1031.045
050.28-4.4910.682-0.375
06-1.4710.697-2.0340.49
07-3.586-3.2171.36-3.326
08-1.3521.28-4.178-2.034
091.369-3.326-4.491-3.94
101.368-3.747-3.747-3.747
11-2.46-0.02-0.6260.875
Standard thresholds
P-value Threshold
0.001 3.777865
0.0005 4.83456
0.0001 7.30382