MotifBMAL1.H12INVIVO.0.PSM.A
Gene (human)ARNTL
(GeneCards)
Gene synonyms (human)BHLHE5, BMAL1, MOP3, PASD3
Gene (mouse)Arntl
Gene synonyms (mouse)Bmal1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length10
ConsensusdbMCACGTGM
GC content60.82%
Information content (bits; total / per base)10.923 / 1.092
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words989

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (36) 0.786 0.92 0.702 0.868 0.718 0.898 2.328 3.588 85.858 179.328
Mouse 30 (186) 0.864 0.96 0.773 0.925 0.809 0.934 2.646 3.729 105.354 464.18

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.801 0.779 0.775 0.762 0.762 0.752
best 0.992 0.985 0.992 0.985 0.992 0.984
Methyl HT-SELEX, 1 experiments median 0.987 0.975 0.986 0.973 0.984 0.97
best 0.987 0.975 0.986 0.973 0.984 0.97
Non-Methyl HT-SELEX, 3 experiments median 0.615 0.583 0.564 0.552 0.54 0.534
best 0.992 0.985 0.992 0.985 0.992 0.984
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyPAS {1.2.5} (TFClass)
TF subfamilyPAS-ARNT {1.2.5.2} (TFClass)
TFClass IDTFClass: 1.2.5.2.3
HGNCHGNC:701
MGIMGI:1096381
EntrezGene (human)GeneID:406
(SSTAR profile)
EntrezGene (mouse)GeneID:11865
(SSTAR profile)
UniProt ID (human)BMAL1_HUMAN
UniProt ID (mouse)BMAL1_MOUSE
UniProt AC (human)O00327
(TFClass)
UniProt AC (mouse)Q9WTL8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 30 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01264.0157.0386.0182.0
02160.0186.0452.0191.0
03335.0480.0170.04.0
0462.0918.04.05.0
05911.08.040.030.0
064.0766.014.0205.0
077.07.0973.02.0
0820.015.05.0949.0
090.00.0985.04.0
10426.0427.022.0114.0
PFM
ACGT
010.2670.1590.390.184
020.1620.1880.4570.193
030.3390.4850.1720.004
040.0630.9280.0040.005
050.9210.0080.040.03
060.0040.7750.0140.207
070.0070.0070.9840.002
080.020.0150.0050.96
090.00.00.9960.004
100.4310.4320.0220.115
PWM
ACGT
010.065-0.450.443-0.304
02-0.431-0.2820.6-0.256
030.3020.66-0.371-3.773
04-1.3631.307-3.773-3.612
051.299-3.243-1.786-2.06
06-3.7731.126-2.762-0.186
07-3.351-3.3511.365-4.203
08-2.439-2.7-3.6121.34
09-4.973-4.9731.377-3.773
100.5410.543-2.351-0.766
Standard thresholds
P-value Threshold
0.001 4.378565
0.0005 5.296525
0.0001 7.7682