MotifBMAL1.H12INVITRO.0.PSM.A
Gene (human)ARNTL
(GeneCards)
Gene synonyms (human)BHLHE5, BMAL1, MOP3, PASD3
Gene (mouse)Arntl
Gene synonyms (mouse)Bmal1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length8
ConsensusCACGTGMb
GC content61.4%
Information content (bits; total / per base)11.216 / 1.402
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words501

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (36) 0.781 0.916 0.688 0.872 0.702 0.886 2.198 3.366 102.418 182.77
Mouse 30 (186) 0.857 0.963 0.753 0.922 0.786 0.931 2.382 3.583 105.682 458.796

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.811 0.812 0.784 0.783 0.768 0.766
best 0.999 0.999 0.998 0.998 0.997 0.996
Methyl HT-SELEX, 1 experiments median 0.998 0.998 0.996 0.994 0.991 0.987
best 0.998 0.998 0.996 0.994 0.991 0.987
Non-Methyl HT-SELEX, 3 experiments median 0.624 0.627 0.572 0.572 0.544 0.545
best 0.999 0.999 0.998 0.998 0.997 0.996
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyPAS {1.2.5} (TFClass)
TF subfamilyPAS-ARNT {1.2.5.2} (TFClass)
TFClass IDTFClass: 1.2.5.2.3
HGNCHGNC:701
MGIMGI:1096381
EntrezGene (human)GeneID:406
(SSTAR profile)
EntrezGene (mouse)GeneID:11865
(SSTAR profile)
UniProt ID (human)BMAL1_HUMAN
UniProt ID (mouse)BMAL1_MOUSE
UniProt AC (human)O00327
(TFClass)
UniProt AC (mouse)Q9WTL8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 30 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
0140.0459.01.01.0
02477.03.016.05.0
030.0444.01.056.0
040.01.0497.03.0
050.01.01.0499.0
060.00.0501.00.0
07248.0191.010.052.0
0864.0205.0130.0102.0
PFM
ACGT
010.080.9160.0020.002
020.9520.0060.0320.01
030.00.8860.0020.112
040.00.0020.9920.006
050.00.0020.0020.996
060.00.01.00.0
070.4950.3810.020.104
080.1280.4090.2590.204
PWM
ACGT
01-1.1161.29-3.905-3.905
021.328-3.327-1.977-2.963
03-4.4021.257-3.905-0.79
04-4.402-3.9051.369-3.327
05-4.402-3.905-3.9051.373
06-4.402-4.4021.377-4.402
070.6770.418-2.396-0.862
08-0.660.4880.037-0.203
Standard thresholds
P-value Threshold
0.001 3.99783
0.0005 5.408075
0.0001 7.90461