| Motif | BMAL1.H12CORE.0.PSM.A |
| Gene (human) | ARNTL (GeneCards) |
| Gene synonyms (human) | BHLHE5, BMAL1, MOP3, PASD3 |
| Gene (mouse) | Arntl |
| Gene synonyms (mouse) | Bmal1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | BMAL1.H12CORE.0.PSM.A |
| Gene (human) | ARNTL (GeneCards) |
| Gene synonyms (human) | BHLHE5, BMAL1, MOP3, PASD3 |
| Gene (mouse) | Arntl |
| Gene synonyms (mouse) | Bmal1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 8 |
| Consensus | CACGTGMb |
| GC content | 61.4% |
| Information content (bits; total / per base) | 11.216 / 1.402 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 501 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 6 (36) | 0.781 | 0.916 | 0.688 | 0.872 | 0.702 | 0.886 | 2.198 | 3.366 | 102.418 | 182.77 |
| Mouse | 30 (186) | 0.857 | 0.963 | 0.753 | 0.922 | 0.786 | 0.931 | 2.382 | 3.583 | 105.682 | 458.796 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.811 | 0.812 | 0.784 | 0.783 | 0.768 | 0.766 |
| best | 0.999 | 0.999 | 0.998 | 0.998 | 0.997 | 0.996 | |
| Methyl HT-SELEX, 1 experiments | median | 0.998 | 0.998 | 0.996 | 0.994 | 0.991 | 0.987 |
| best | 0.998 | 0.998 | 0.996 | 0.994 | 0.991 | 0.987 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.624 | 0.627 | 0.572 | 0.572 | 0.544 | 0.545 |
| best | 0.999 | 0.999 | 0.998 | 0.998 | 0.997 | 0.996 | |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | PAS {1.2.5} (TFClass) |
| TF subfamily | PAS-ARNT {1.2.5.2} (TFClass) |
| TFClass ID | TFClass: 1.2.5.2.3 |
| HGNC | HGNC:701 |
| MGI | MGI:1096381 |
| EntrezGene (human) | GeneID:406 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:11865 (SSTAR profile) |
| UniProt ID (human) | BMAL1_HUMAN |
| UniProt ID (mouse) | BMAL1_MOUSE |
| UniProt AC (human) | O00327 (TFClass) |
| UniProt AC (mouse) | Q9WTL8 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 6 human, 30 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | BMAL1.H12CORE.0.PSM.A.pcm |
| PWM | BMAL1.H12CORE.0.PSM.A.pwm |
| PFM | BMAL1.H12CORE.0.PSM.A.pfm |
| Alignment | BMAL1.H12CORE.0.PSM.A.words.tsv |
| Threshold to P-value map | BMAL1.H12CORE.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | BMAL1.H12CORE.0.PSM.A_jaspar_format.txt |
| MEME format | BMAL1.H12CORE.0.PSM.A_meme_format.meme |
| Transfac format | BMAL1.H12CORE.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 40.0 | 459.0 | 1.0 | 1.0 |
| 02 | 477.0 | 3.0 | 16.0 | 5.0 |
| 03 | 0.0 | 444.0 | 1.0 | 56.0 |
| 04 | 0.0 | 1.0 | 497.0 | 3.0 |
| 05 | 0.0 | 1.0 | 1.0 | 499.0 |
| 06 | 0.0 | 0.0 | 501.0 | 0.0 |
| 07 | 248.0 | 191.0 | 10.0 | 52.0 |
| 08 | 64.0 | 205.0 | 130.0 | 102.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.08 | 0.916 | 0.002 | 0.002 |
| 02 | 0.952 | 0.006 | 0.032 | 0.01 |
| 03 | 0.0 | 0.886 | 0.002 | 0.112 |
| 04 | 0.0 | 0.002 | 0.992 | 0.006 |
| 05 | 0.0 | 0.002 | 0.002 | 0.996 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.495 | 0.381 | 0.02 | 0.104 |
| 08 | 0.128 | 0.409 | 0.259 | 0.204 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.116 | 1.29 | -3.905 | -3.905 |
| 02 | 1.328 | -3.327 | -1.977 | -2.963 |
| 03 | -4.402 | 1.257 | -3.905 | -0.79 |
| 04 | -4.402 | -3.905 | 1.369 | -3.327 |
| 05 | -4.402 | -3.905 | -3.905 | 1.373 |
| 06 | -4.402 | -4.402 | 1.377 | -4.402 |
| 07 | 0.677 | 0.418 | -2.396 | -0.862 |
| 08 | -0.66 | 0.488 | 0.037 | -0.203 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.99783 |
| 0.0005 | 5.408075 |
| 0.0001 | 7.90461 |