BHE41.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BHE41.H12INVITRO.0.PSM.A
Gene (human)	BHLHE41 (GeneCards)
Gene synonyms (human)	BHLHB3, DEC2, SHARP1
Gene (mouse)	Bhlhe41
Gene synonyms (mouse)	Bhlhb3, Dec2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	ndGTCACGTGMn
GC content	60.86%
Information content (bits; total / per base)	15.157 / 1.263
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	5764

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	2 (14)	0.775	0.783	0.755	0.769	0.865	0.872	3.488	3.561	364.303	435.194

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.999	0.997	0.951	0.955	0.771	0.805
Overall, 6 experiments	best	1.0	0.999	1.0	0.999	1.0	0.999
Methyl HT-SELEX, 1 experiments	median	0.999	0.998	0.999	0.998	0.991	0.99
Methyl HT-SELEX, 1 experiments	best	0.999	0.998	0.999	0.998	0.991	0.99
Non-Methyl HT-SELEX, 5 experiments	median	0.998	0.997	0.904	0.912	0.717	0.756
Non-Methyl HT-SELEX, 5 experiments	best	1.0	0.999	1.0	0.999	1.0	0.999

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Hairy-related {1.2.4} (TFClass)
TF subfamily	HAIRY {1.2.4.1} (TFClass)
TFClass ID	TFClass: 1.2.4.1.13
HGNC	HGNC:16617
MGI	MGI:1930704
EntrezGene (human)	GeneID:79365 (SSTAR profile)
EntrezGene (mouse)	GeneID:79362 (SSTAR profile)
UniProt ID (human)	BHE41_HUMAN
UniProt ID (mouse)	BHE41_MOUSE
UniProt AC (human)	Q9C0J9 (TFClass)
UniProt AC (mouse)	Q99PV5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 2 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	BHE41.H12INVITRO.0.PSM.A.pcm
PWM	BHE41.H12INVITRO.0.PSM.A.pwm
PFM	BHE41.H12INVITRO.0.PSM.A.pfm
Alignment	BHE41.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	BHE41.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	BHE41.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	BHE41.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	BHE41.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	BHE41.H12INVITRO.0.PSM.A_homer_format_0.001.txt BHE41.H12INVITRO.0.PSM.A_homer_format_0.0005.txt BHE41.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1645.75	1220.75	1541.75	1355.75
02	1652.75	821.75	2301.75	987.75
03	854.0	128.0	4745.0	37.0
04	0.0	0.0	1346.0	4418.0
05	0.0	5764.0	0.0	0.0
06	5764.0	0.0	0.0	0.0
07	0.0	5764.0	0.0	0.0
08	0.0	0.0	5764.0	0.0
09	0.0	0.0	0.0	5764.0
10	0.0	0.0	5764.0	0.0
11	1510.0	3539.0	163.0	552.0
12	959.75	1545.75	1686.75	1571.75

PFM

	A	C	G	T
01	0.286	0.212	0.267	0.235
02	0.287	0.143	0.399	0.171
03	0.148	0.022	0.823	0.006
04	0.0	0.0	0.234	0.766
05	0.0	1.0	0.0	0.0
06	1.0	0.0	0.0	0.0
07	0.0	1.0	0.0	0.0
08	0.0	0.0	1.0	0.0
09	0.0	0.0	0.0	1.0
10	0.0	0.0	1.0	0.0
11	0.262	0.614	0.028	0.096
12	0.167	0.268	0.293	0.273

PWM

	A	C	G	T
01	0.133	-0.166	0.067	-0.061
02	0.137	-0.561	0.468	-0.377
03	-0.522	-2.406	1.191	-3.607
04	-6.502	-6.502	-0.068	1.119
05	-6.502	1.385	-6.502	-6.502
06	1.385	-6.502	-6.502	-6.502
07	-6.502	1.385	-6.502	-6.502
08	-6.502	-6.502	1.385	-6.502
09	-6.502	-6.502	-6.502	1.385
10	-6.502	-6.502	1.385	-6.502
11	0.047	0.898	-2.168	-0.957
12	-0.406	0.07	0.157	0.087

Standard thresholds

P-value	Threshold
0.001	-0.290015
0.0005	1.44424
0.0001	4.570235