BHE22.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BHE22.H12INVIVO.0.SM.D
Gene (human)	BHLHE22 (GeneCards)
Gene synonyms (human)	BHLHB5, TNRC20
Gene (mouse)	Bhlhe22
Gene synonyms (mouse)	Bhlhb5
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	11
Consensus	nvCATATGKYn
GC content	41.68%
Information content (bits; total / per base)	12.312 / 1.119
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9849

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.995	0.991	0.955	0.951	0.803	0.817
Overall, 4 experiments	best	0.999	0.999	0.995	0.993	0.945	0.943
Methyl HT-SELEX, 1 experiments	median	0.991	0.987	0.935	0.925	0.816	0.814
Methyl HT-SELEX, 1 experiments	best	0.991	0.987	0.935	0.925	0.816	0.814
Non-Methyl HT-SELEX, 3 experiments	median	0.998	0.996	0.976	0.976	0.789	0.82
Non-Methyl HT-SELEX, 3 experiments	best	0.999	0.999	0.995	0.993	0.945	0.943

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	Neurogenin-ATO {1.2.3.4} (TFClass)
TFClass ID	TFClass: 1.2.3.4.11
HGNC	HGNC:11963
MGI	MGI:1930001
EntrezGene (human)	GeneID:27319 (SSTAR profile)
EntrezGene (mouse)	GeneID:59058 (SSTAR profile)
UniProt ID (human)	BHE22_HUMAN
UniProt ID (mouse)	BHE22_MOUSE
UniProt AC (human)	Q8NFJ8 (TFClass)
UniProt AC (mouse)	Q8C6A8 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	BHE22.H12INVIVO.0.SM.D.pcm
PWM	BHE22.H12INVIVO.0.SM.D.pwm
PFM	BHE22.H12INVIVO.0.SM.D.pfm
Alignment	BHE22.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	BHE22.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	BHE22.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	BHE22.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	BHE22.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	BHE22.H12INVIVO.0.SM.D_homer_format_0.001.txt BHE22.H12INVIVO.0.SM.D_homer_format_0.0005.txt BHE22.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2854.0	1618.0	3557.0	1820.0
02	1774.25	4749.25	2500.25	825.25
03	464.0	9062.0	248.0	75.0
04	8884.0	20.0	500.0	445.0
05	0.0	48.0	73.0	9728.0
06	9811.0	17.0	21.0	0.0
07	112.0	11.0	11.0	9715.0
08	0.0	0.0	9847.0	2.0
09	16.0	1322.0	4743.0	3768.0
10	619.5	1257.5	729.5	7242.5
11	2124.5	2158.5	2664.5	2901.5

PFM

	A	C	G	T
01	0.29	0.164	0.361	0.185
02	0.18	0.482	0.254	0.084
03	0.047	0.92	0.025	0.008
04	0.902	0.002	0.051	0.045
05	0.0	0.005	0.007	0.988
06	0.996	0.002	0.002	0.0
07	0.011	0.001	0.001	0.986
08	0.0	0.0	1.0	0.0
09	0.002	0.134	0.482	0.383
10	0.063	0.128	0.074	0.735
11	0.216	0.219	0.271	0.295

PWM

	A	C	G	T
01	0.148	-0.419	0.368	-0.302
02	-0.327	0.656	0.015	-1.091
03	-1.665	1.302	-2.287	-3.462
04	1.283	-4.705	-1.591	-1.707
05	-6.977	-3.892	-3.488	1.373
06	1.382	-4.85	-4.661	-6.977
07	-3.071	-5.222	-5.222	1.372
08	-6.977	-6.977	1.385	-6.351
09	-4.903	-0.621	0.655	0.425
10	-1.377	-0.671	-1.214	1.078
11	-0.147	-0.132	0.079	0.164

Standard thresholds

P-value	Threshold
0.001	3.532235
0.0005	4.7821
0.0001	7.39962