MotifBHE22.H12CORE.0.SM.B
Gene (human)BHLHE22
(GeneCards)
Gene synonyms (human)BHLHB5, TNRC20
Gene (mouse)Bhlhe22
Gene synonyms (mouse)Bhlhb5
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnvCATATGKYn
GC content41.68%
Information content (bits; total / per base)12.312 / 1.119
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9849

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.995 0.991 0.955 0.951 0.803 0.817
best 0.999 0.999 0.995 0.993 0.945 0.943
Methyl HT-SELEX, 1 experiments median 0.991 0.987 0.935 0.925 0.816 0.814
best 0.991 0.987 0.935 0.925 0.816 0.814
Non-Methyl HT-SELEX, 3 experiments median 0.998 0.996 0.976 0.976 0.789 0.82
best 0.999 0.999 0.995 0.993 0.945 0.943
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyNeurogenin-ATO {1.2.3.4} (TFClass)
TFClass IDTFClass: 1.2.3.4.11
HGNCHGNC:11963
MGIMGI:1930001
EntrezGene (human)GeneID:27319
(SSTAR profile)
EntrezGene (mouse)GeneID:59058
(SSTAR profile)
UniProt ID (human)BHE22_HUMAN
UniProt ID (mouse)BHE22_MOUSE
UniProt AC (human)Q8NFJ8
(TFClass)
UniProt AC (mouse)Q8C6A8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012854.01618.03557.01820.0
021774.254749.252500.25825.25
03464.09062.0248.075.0
048884.020.0500.0445.0
050.048.073.09728.0
069811.017.021.00.0
07112.011.011.09715.0
080.00.09847.02.0
0916.01322.04743.03768.0
10619.51257.5729.57242.5
112124.52158.52664.52901.5
PFM
ACGT
010.290.1640.3610.185
020.180.4820.2540.084
030.0470.920.0250.008
040.9020.0020.0510.045
050.00.0050.0070.988
060.9960.0020.0020.0
070.0110.0010.0010.986
080.00.01.00.0
090.0020.1340.4820.383
100.0630.1280.0740.735
110.2160.2190.2710.295
PWM
ACGT
010.148-0.4190.368-0.302
02-0.3270.6560.015-1.091
03-1.6651.302-2.287-3.462
041.283-4.705-1.591-1.707
05-6.977-3.892-3.4881.373
061.382-4.85-4.661-6.977
07-3.071-5.222-5.2221.372
08-6.977-6.9771.385-6.351
09-4.903-0.6210.6550.425
10-1.377-0.671-1.2141.078
11-0.147-0.1320.0790.164
Standard thresholds
P-value Threshold
0.001 3.532235
0.0005 4.7821
0.0001 7.39962