BHA15.H12RSNP.1.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BHA15.H12RSNP.1.SM.D
Gene (human)	BHLHA15 (GeneCards)
Gene synonyms (human)	BHLHB8, MIST1
Gene (mouse)	Bhlha15
Gene synonyms (mouse)	Bhlhb8, Mist1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	14
Consensus	nnbRMCATATGGhn
GC content	46.58%
Information content (bits; total / per base)	15.302 / 1.093
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	332

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (17)	0.869	0.892	0.687	0.768	0.686	0.751	1.905	3.036	52.62	152.328

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.964	0.955	0.854	0.852	0.748	0.756
Overall, 4 experiments	best	0.999	0.998	0.997	0.995	0.98	0.976
Methyl HT-SELEX, 1 experiments	median	0.999	0.998	0.997	0.995	0.98	0.976
Methyl HT-SELEX, 1 experiments	best	0.999	0.998	0.997	0.995	0.98	0.976
Non-Methyl HT-SELEX, 3 experiments	median	0.944	0.937	0.759	0.771	0.636	0.664
Non-Methyl HT-SELEX, 3 experiments	best	0.984	0.974	0.949	0.932	0.861	0.848

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	Neurogenin-ATO {1.2.3.4} (TFClass)
TFClass ID	TFClass: 1.2.3.4.16
HGNC	HGNC:22265
MGI	MGI:891976
EntrezGene (human)	GeneID:168620 (SSTAR profile)
EntrezGene (mouse)	GeneID:17341 (SSTAR profile)
UniProt ID (human)	BHA15_HUMAN
UniProt ID (mouse)	BHA15_MOUSE
UniProt AC (human)	Q7RTS1 (TFClass)
UniProt AC (mouse)	Q9QYC3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	BHA15.H12RSNP.1.SM.D.pcm
PWM	BHA15.H12RSNP.1.SM.D.pwm
PFM	BHA15.H12RSNP.1.SM.D.pfm
Alignment	BHA15.H12RSNP.1.SM.D.words.tsv
Threshold to P-value map	BHA15.H12RSNP.1.SM.D.thr
Motif in other formats
JASPAR format	BHA15.H12RSNP.1.SM.D_jaspar_format.txt
MEME format	BHA15.H12RSNP.1.SM.D_meme_format.meme
Transfac format	BHA15.H12RSNP.1.SM.D_transfac_format.txt
Homer format	BHA15.H12RSNP.1.SM.D_homer_format_0.001.txt BHA15.H12RSNP.1.SM.D_homer_format_0.0005.txt BHA15.H12RSNP.1.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	51.75	90.75	103.75	85.75
02	60.25	76.25	130.25	65.25
03	26.0	66.0	145.0	95.0
04	243.0	4.0	67.0	18.0
05	141.0	172.0	19.0	0.0
06	0.0	332.0	0.0	0.0
07	332.0	0.0	0.0	0.0
08	0.0	0.0	4.0	328.0
09	328.0	4.0	0.0	0.0
10	0.0	0.0	0.0	332.0
11	0.0	0.0	332.0	0.0
12	0.0	17.0	297.0	18.0
13	125.75	93.75	45.75	66.75
14	98.25	81.25	84.25	68.25

PFM

	A	C	G	T
01	0.156	0.273	0.313	0.258
02	0.181	0.23	0.392	0.197
03	0.078	0.199	0.437	0.286
04	0.732	0.012	0.202	0.054
05	0.425	0.518	0.057	0.0
06	0.0	1.0	0.0	0.0
07	1.0	0.0	0.0	0.0
08	0.0	0.0	0.012	0.988
09	0.988	0.012	0.0	0.0
10	0.0	0.0	0.0	1.0
11	0.0	0.0	1.0	0.0
12	0.0	0.051	0.895	0.054
13	0.379	0.282	0.138	0.201
14	0.296	0.245	0.254	0.206

PWM

	A	C	G	T
01	-0.462	0.088	0.22	0.032
02	-0.314	-0.083	0.444	-0.236
03	-1.124	-0.225	0.551	0.133
04	1.063	-2.74	-0.21	-1.468
05	0.523	0.72	-1.418	-4.064
06	-4.064	1.373	-4.064	-4.064
07	1.373	-4.064	-4.064	-4.064
08	-4.064	-4.064	-2.74	1.361
09	1.361	-2.74	-4.064	-4.064
10	-4.064	-4.064	-4.064	1.373
11	-4.064	-4.064	1.373	-4.064
12	-4.064	-1.521	1.262	-1.468
13	0.41	0.12	-0.582	-0.214
14	0.166	-0.021	0.015	-0.192

Standard thresholds

P-value	Threshold
0.001	2.30971
0.0005	3.704915
0.0001	6.372315