BHA15.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BHA15.H12INVIVO.0.P.B
Gene (human)	BHLHA15 (GeneCards)
Gene synonyms (human)	BHLHB8, MIST1
Gene (mouse)	Bhlha15
Gene synonyms (mouse)	Bhlhb8, Mist1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	vRRCAGCTGK
GC content	60.24%
Information content (bits; total / per base)	12.275 / 1.228
Data sources	ChIP-Seq
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (17)	0.923	0.944	0.809	0.863	0.879	0.899	2.84	3.012	219.161	558.26

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.938	0.905	0.847	0.827	0.736	0.735
Overall, 4 experiments	best	0.986	0.977	0.979	0.965	0.971	0.955
Methyl HT-SELEX, 1 experiments	median	0.986	0.977	0.979	0.965	0.971	0.955
Methyl HT-SELEX, 1 experiments	best	0.986	0.977	0.979	0.965	0.971	0.955
Non-Methyl HT-SELEX, 3 experiments	median	0.921	0.882	0.755	0.748	0.637	0.653
Non-Methyl HT-SELEX, 3 experiments	best	0.955	0.927	0.939	0.905	0.835	0.816

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	Neurogenin-ATO {1.2.3.4} (TFClass)
TFClass ID	TFClass: 1.2.3.4.16
HGNC	HGNC:22265
MGI	MGI:891976
EntrezGene (human)	GeneID:168620 (SSTAR profile)
EntrezGene (mouse)	GeneID:17341 (SSTAR profile)
UniProt ID (human)	BHA15_HUMAN
UniProt ID (mouse)	BHA15_MOUSE
UniProt AC (human)	Q7RTS1 (TFClass)
UniProt AC (mouse)	Q9QYC3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	BHA15.H12INVIVO.0.P.B.pcm
PWM	BHA15.H12INVIVO.0.P.B.pwm
PFM	BHA15.H12INVIVO.0.P.B.pfm
Alignment	BHA15.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	BHA15.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	BHA15.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	BHA15.H12INVIVO.0.P.B_meme_format.meme
Transfac format	BHA15.H12INVIVO.0.P.B_transfac_format.txt
Homer format	BHA15.H12INVIVO.0.P.B_homer_format_0.001.txt BHA15.H12INVIVO.0.P.B_homer_format_0.0005.txt BHA15.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	292.0	300.0	310.0	95.0
02	582.0	153.0	210.0	52.0
03	450.0	156.0	386.0	5.0
04	1.0	996.0	0.0	0.0
05	991.0	0.0	2.0	4.0
06	2.0	2.0	774.0	219.0
07	95.0	895.0	4.0	3.0
08	17.0	3.0	2.0	975.0
09	1.0	1.0	988.0	7.0
10	6.0	92.0	732.0	167.0

PFM

	A	C	G	T
01	0.293	0.301	0.311	0.095
02	0.584	0.153	0.211	0.052
03	0.451	0.156	0.387	0.005
04	0.001	0.999	0.0	0.0
05	0.994	0.0	0.002	0.004
06	0.002	0.002	0.776	0.22
07	0.095	0.898	0.004	0.003
08	0.017	0.003	0.002	0.978
09	0.001	0.001	0.991	0.007
10	0.006	0.092	0.734	0.168

PWM

	A	C	G	T
01	0.157	0.184	0.217	-0.953
02	0.844	-0.484	-0.17	-1.541
03	0.588	-0.464	0.435	-3.619
04	-4.522	1.38	-4.979	-4.979
05	1.375	-4.979	-4.21	-3.78
06	-4.21	-4.21	1.128	-0.128
07	-0.953	1.273	-3.78	-3.972
08	-2.595	-3.972	-4.21	1.359
09	-4.522	-4.522	1.372	-3.359
10	-3.481	-0.985	1.073	-0.397

Standard thresholds

P-value	Threshold
0.001	3.60642
0.0005	4.78302
0.0001	7.526325