BHA15.H12INVITRO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BHA15.H12INVITRO.1.SM.B
Gene (human)	BHLHA15 (GeneCards)
Gene synonyms (human)	BHLHB8, MIST1
Gene (mouse)	Bhlha15
Gene synonyms (mouse)	Bhlhb8, Mist1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	nRMCATATGSn
GC content	43.52%
Information content (bits; total / per base)	14.263 / 1.297
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2030

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (17)	0.826	0.851	0.622	0.72	0.659	0.732	1.814	3.029	46.301	113.161

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.963	0.956	0.858	0.855	0.752	0.758
Overall, 4 experiments	best	0.999	0.998	0.997	0.996	0.974	0.97
Methyl HT-SELEX, 1 experiments	median	0.999	0.998	0.997	0.996	0.974	0.97
Methyl HT-SELEX, 1 experiments	best	0.999	0.998	0.997	0.996	0.974	0.97
Non-Methyl HT-SELEX, 3 experiments	median	0.943	0.937	0.768	0.777	0.64	0.668
Non-Methyl HT-SELEX, 3 experiments	best	0.984	0.974	0.949	0.933	0.863	0.848

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	Neurogenin-ATO {1.2.3.4} (TFClass)
TFClass ID	TFClass: 1.2.3.4.16
HGNC	HGNC:22265
MGI	MGI:891976
EntrezGene (human)	GeneID:168620 (SSTAR profile)
EntrezGene (mouse)	GeneID:17341 (SSTAR profile)
UniProt ID (human)	BHA15_HUMAN
UniProt ID (mouse)	BHA15_MOUSE
UniProt AC (human)	Q7RTS1 (TFClass)
UniProt AC (mouse)	Q9QYC3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	BHA15.H12INVITRO.1.SM.B.pcm
PWM	BHA15.H12INVITRO.1.SM.B.pwm
PFM	BHA15.H12INVITRO.1.SM.B.pfm
Alignment	BHA15.H12INVITRO.1.SM.B.words.tsv
Threshold to P-value map	BHA15.H12INVITRO.1.SM.B.thr
Motif in other formats
JASPAR format	BHA15.H12INVITRO.1.SM.B_jaspar_format.txt
MEME format	BHA15.H12INVITRO.1.SM.B_meme_format.meme
Transfac format	BHA15.H12INVITRO.1.SM.B_transfac_format.txt
Homer format	BHA15.H12INVITRO.1.SM.B_homer_format_0.001.txt BHA15.H12INVITRO.1.SM.B_homer_format_0.0005.txt BHA15.H12INVITRO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	348.25	574.25	635.25	472.25
02	1459.75	20.75	421.75	127.75
03	750.0	1154.0	126.0	0.0
04	0.0	2030.0	0.0	0.0
05	2029.0	0.0	1.0	0.0
06	0.0	0.0	12.0	2018.0
07	2022.0	8.0	0.0	0.0
08	0.0	3.0	0.0	2027.0
09	0.0	0.0	2029.0	1.0
10	28.75	327.75	1377.75	295.75
11	607.25	559.25	437.25	426.25

PFM

	A	C	G	T
01	0.172	0.283	0.313	0.233
02	0.719	0.01	0.208	0.063
03	0.369	0.568	0.062	0.0
04	0.0	1.0	0.0	0.0
05	1.0	0.0	0.0	0.0
06	0.0	0.0	0.006	0.994
07	0.996	0.004	0.0	0.0
08	0.0	0.001	0.0	0.999
09	0.0	0.0	1.0	0.0
10	0.014	0.161	0.679	0.146
11	0.299	0.275	0.215	0.21

PWM

	A	C	G	T
01	-0.375	0.123	0.224	-0.072
02	1.054	-3.113	-0.184	-1.368
03	0.389	0.819	-1.382	-5.589
04	-5.589	1.383	-5.589	-5.589
05	1.383	-5.589	-5.167	-5.589
06	-5.589	-5.589	-3.601	1.378
07	1.38	-3.94	-5.589	-5.589
08	-5.589	-4.643	-5.589	1.382
09	-5.589	-5.589	1.383	-5.167
10	-2.81	-0.435	0.996	-0.537
11	0.179	0.097	-0.148	-0.174

Standard thresholds

P-value	Threshold
0.001	1.739955
0.0005	2.94773
0.0001	6.495425