BHA15.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BHA15.H12INVITRO.0.P.B
Gene (human)	BHLHA15 (GeneCards)
Gene synonyms (human)	BHLHB8, MIST1
Gene (mouse)	Bhlha15
Gene synonyms (mouse)	Bhlhb8, Mist1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	vvMRCAGCTGKv
GC content	60.27%
Information content (bits; total / per base)	12.77 / 1.064
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (17)	0.922	0.942	0.806	0.852	0.882	0.905	2.954	3.195	218.824	548.222

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.938	0.905	0.849	0.828	0.74	0.737
Overall, 4 experiments	best	0.986	0.977	0.979	0.966	0.972	0.956
Methyl HT-SELEX, 1 experiments	median	0.986	0.977	0.979	0.966	0.972	0.956
Methyl HT-SELEX, 1 experiments	best	0.986	0.977	0.979	0.966	0.972	0.956
Non-Methyl HT-SELEX, 3 experiments	median	0.92	0.881	0.758	0.749	0.641	0.655
Non-Methyl HT-SELEX, 3 experiments	best	0.956	0.928	0.94	0.906	0.84	0.82

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	Neurogenin-ATO {1.2.3.4} (TFClass)
TFClass ID	TFClass: 1.2.3.4.16
HGNC	HGNC:22265
MGI	MGI:891976
EntrezGene (human)	GeneID:168620 (SSTAR profile)
EntrezGene (mouse)	GeneID:17341 (SSTAR profile)
UniProt ID (human)	BHA15_HUMAN
UniProt ID (mouse)	BHA15_MOUSE
UniProt AC (human)	Q7RTS1 (TFClass)
UniProt AC (mouse)	Q9QYC3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	BHA15.H12INVITRO.0.P.B.pcm
PWM	BHA15.H12INVITRO.0.P.B.pwm
PFM	BHA15.H12INVITRO.0.P.B.pfm
Alignment	BHA15.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	BHA15.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	BHA15.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	BHA15.H12INVITRO.0.P.B_meme_format.meme
Transfac format	BHA15.H12INVITRO.0.P.B_transfac_format.txt
Homer format	BHA15.H12INVITRO.0.P.B_homer_format_0.001.txt BHA15.H12INVITRO.0.P.B_homer_format_0.0005.txt BHA15.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	263.0	226.0	401.0	109.0
02	271.0	327.0	309.0	92.0
03	598.0	222.0	159.0	20.0
04	498.0	161.0	339.0	1.0
05	2.0	997.0	0.0	0.0
06	994.0	0.0	1.0	4.0
07	0.0	1.0	829.0	169.0
08	118.0	874.0	3.0	4.0
09	2.0	1.0	0.0	996.0
10	0.0	0.0	991.0	8.0
11	7.0	144.0	695.0	153.0
12	306.0	372.0	173.0	148.0

PFM

	A	C	G	T
01	0.263	0.226	0.401	0.109
02	0.271	0.327	0.309	0.092
03	0.599	0.222	0.159	0.02
04	0.498	0.161	0.339	0.001
05	0.002	0.998	0.0	0.0
06	0.995	0.0	0.001	0.004
07	0.0	0.001	0.83	0.169
08	0.118	0.875	0.003	0.004
09	0.002	0.001	0.0	0.997
10	0.0	0.0	0.992	0.008
11	0.007	0.144	0.696	0.153
12	0.306	0.372	0.173	0.148

PWM

	A	C	G	T
01	0.051	-0.099	0.471	-0.82
02	0.081	0.268	0.212	-0.987
03	0.869	-0.117	-0.448	-2.449
04	0.687	-0.435	0.304	-4.524
05	-4.212	1.379	-4.981	-4.981
06	1.376	-4.981	-4.524	-3.782
07	-4.981	-4.524	1.195	-0.387
08	-0.742	1.248	-3.974	-3.782
09	-4.212	-4.524	-4.981	1.378
10	-4.981	-4.981	1.373	-3.252
11	-3.361	-0.546	1.019	-0.486
12	0.202	0.396	-0.364	-0.519

Standard thresholds

P-value	Threshold
0.001	3.206015
0.0005	4.47321
0.0001	7.50571