BCL6B.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BCL6B.H12INVITRO.0.PSM.A
Gene (human)	BCL6B (GeneCards)
Gene synonyms (human)	BAZF, ZNF62
Gene (mouse)	Bcl6b
Gene synonyms (mouse)	Bazf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	nGCTTTCGAGGAAWn
GC content	43.46%
Information content (bits; total / per base)	22.362 / 1.491
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	8792

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.79	0.843	0.761	0.836	0.827	0.879	3.646	4.121	205.456	230.387

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	1.0	1.0	0.932	0.941	0.728	0.777
Overall, 2 experiments	best	1.0	1.0	0.992	0.992	0.782	0.825
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.873	0.89	0.674	0.729
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.873	0.89	0.674	0.729
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.992	0.992	0.782	0.825
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.992	0.992	0.782	0.825

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	BCL6 {2.3.3.22} (TFClass)
TFClass ID	TFClass: 2.3.3.22.1
HGNC	HGNC:1002
MGI	MGI:1278332
EntrezGene (human)	GeneID:255877 (SSTAR profile)
EntrezGene (mouse)	GeneID:12029 (SSTAR profile)
UniProt ID (human)	BCL6B_HUMAN
UniProt ID (mouse)	BCL6B_MOUSE
UniProt AC (human)	Q8N143 (TFClass)
UniProt AC (mouse)	O88282 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	BCL6B.H12INVITRO.0.PSM.A.pcm
PWM	BCL6B.H12INVITRO.0.PSM.A.pwm
PFM	BCL6B.H12INVITRO.0.PSM.A.pfm
Alignment	BCL6B.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	BCL6B.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	BCL6B.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	BCL6B.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	BCL6B.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	BCL6B.H12INVITRO.0.PSM.A_homer_format_0.001.txt BCL6B.H12INVITRO.0.PSM.A_homer_format_0.0005.txt BCL6B.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1476.25	2051.25	1822.25	3442.25
02	1341.5	153.5	6925.5	371.5
03	27.0	8691.0	10.0	64.0
04	345.0	7.0	1.0	8439.0
05	27.0	40.0	19.0	8706.0
06	0.0	0.0	0.0	8792.0
07	0.0	8791.0	0.0	1.0
08	0.0	58.0	5543.0	3191.0
09	8790.0	0.0	1.0	1.0
10	2.0	0.0	8790.0	0.0
11	0.0	0.0	8792.0	0.0
12	8778.0	0.0	11.0	3.0
13	8782.0	0.0	2.0	8.0
14	1426.0	1308.0	106.0	5952.0
15	1809.0	1543.0	2653.0	2787.0

PFM

	A	C	G	T
01	0.168	0.233	0.207	0.392
02	0.153	0.017	0.788	0.042
03	0.003	0.989	0.001	0.007
04	0.039	0.001	0.0	0.96
05	0.003	0.005	0.002	0.99
06	0.0	0.0	0.0	1.0
07	0.0	1.0	0.0	0.0
08	0.0	0.007	0.63	0.363
09	1.0	0.0	0.0	0.0
10	0.0	0.0	1.0	0.0
11	0.0	0.0	1.0	0.0
12	0.998	0.0	0.001	0.0
13	0.999	0.0	0.0	0.001
14	0.162	0.149	0.012	0.677
15	0.206	0.176	0.302	0.317

PWM

	A	C	G	T
01	-0.398	-0.069	-0.187	0.448
02	-0.493	-2.648	1.147	-1.773
03	-4.32	1.374	-5.189	-3.503
04	-1.846	-5.47	-6.511	1.345
05	-4.32	-3.952	-4.639	1.376
06	-6.876	-6.876	-6.876	1.386
07	-6.876	1.385	-6.876	-6.511
08	-6.876	-3.597	0.924	0.372
09	1.385	-6.876	-6.511	-6.511
10	-6.245	-6.876	1.385	-6.876
11	-6.876	-6.876	1.386	-6.876
12	1.384	-6.876	-5.111	-6.034
13	1.384	-6.876	-6.245	-5.367
14	-0.432	-0.518	-3.012	0.996
15	-0.195	-0.353	0.188	0.237

Standard thresholds

P-value	Threshold
0.001	-8.37429
0.0005	-6.09634
0.0001	-0.94449