BCL6B.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BCL6B.H12CORE.0.PSM.A
Gene (human)	BCL6B (GeneCards)
Gene synonyms (human)	BAZF, ZNF62
Gene (mouse)	Bcl6b
Gene synonyms (mouse)	Bazf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	ddMYYTCYARGRAhn
GC content	39.7%
Information content (bits; total / per base)	12.191 / 0.813
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.859	0.907	0.812	0.865	0.858	0.909	3.962	4.404	225.658	236.602

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	1.0	1.0	0.925	0.935	0.713	0.767
Overall, 2 experiments	best	1.0	1.0	0.985	0.985	0.767	0.814
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.864	0.884	0.659	0.72
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.864	0.884	0.659	0.72
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.985	0.985	0.767	0.814
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.985	0.985	0.767	0.814

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	BCL6 {2.3.3.22} (TFClass)
TFClass ID	TFClass: 2.3.3.22.1
HGNC	HGNC:1002
MGI	MGI:1278332
EntrezGene (human)	GeneID:255877 (SSTAR profile)
EntrezGene (mouse)	GeneID:12029 (SSTAR profile)
UniProt ID (human)	BCL6B_HUMAN
UniProt ID (mouse)	BCL6B_MOUSE
UniProt AC (human)	Q8N143 (TFClass)
UniProt AC (mouse)	O88282 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	BCL6B.H12CORE.0.PSM.A.pcm
PWM	BCL6B.H12CORE.0.PSM.A.pwm
PFM	BCL6B.H12CORE.0.PSM.A.pfm
Alignment	BCL6B.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	BCL6B.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	BCL6B.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	BCL6B.H12CORE.0.PSM.A_meme_format.meme
Transfac format	BCL6B.H12CORE.0.PSM.A_transfac_format.txt
Homer format	BCL6B.H12CORE.0.PSM.A_homer_format_0.001.txt BCL6B.H12CORE.0.PSM.A_homer_format_0.0005.txt BCL6B.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	214.0	163.0	197.0	424.0
02	186.0	107.0	475.0	230.0
03	134.0	683.0	65.0	116.0
04	128.0	197.0	17.0	656.0
05	56.0	175.0	39.0	728.0
06	8.0	9.0	9.0	972.0
07	6.0	900.0	6.0	86.0
08	44.0	340.0	84.0	530.0
09	960.0	13.0	15.0	10.0
10	192.0	3.0	741.0	62.0
11	50.0	28.0	820.0	100.0
12	775.0	74.0	92.0	57.0
13	827.0	41.0	26.0	104.0
14	350.0	133.0	81.0	434.0
15	220.0	190.0	220.0	368.0

PFM

	A	C	G	T
01	0.214	0.163	0.197	0.425
02	0.186	0.107	0.476	0.23
03	0.134	0.684	0.065	0.116
04	0.128	0.197	0.017	0.657
05	0.056	0.175	0.039	0.729
06	0.008	0.009	0.009	0.974
07	0.006	0.902	0.006	0.086
08	0.044	0.341	0.084	0.531
09	0.962	0.013	0.015	0.01
10	0.192	0.003	0.742	0.062
11	0.05	0.028	0.822	0.1
12	0.777	0.074	0.092	0.057
13	0.829	0.041	0.026	0.104
14	0.351	0.133	0.081	0.435
15	0.22	0.19	0.22	0.369

PWM

	A	C	G	T
01	-0.152	-0.422	-0.234	0.527
02	-0.291	-0.838	0.641	-0.081
03	-0.616	1.003	-1.326	-0.758
04	-0.661	-0.234	-2.596	0.962
05	-1.471	-0.352	-1.819	1.066
06	-3.252	-3.154	-3.154	1.355
07	-3.482	1.278	-3.482	-1.052
08	-1.704	0.308	-1.075	0.75
09	1.342	-2.837	-2.709	-3.065
10	-0.26	-3.973	1.084	-1.372
11	-1.58	-2.134	1.185	-0.904
12	1.129	-1.199	-0.986	-1.453
13	1.194	-1.772	-2.204	-0.865
14	0.336	-0.623	-1.111	0.551
15	-0.125	-0.27	-0.125	0.386

Standard thresholds

P-value	Threshold
0.001	4.17226
0.0005	5.12556
0.0001	7.09651