Motif | BCL6.H12CORE.0.PSM.A |
Gene (human) | BCL6 (GeneCards) |
Gene synonyms (human) | BCL5, LAZ3, ZBTB27, ZNF51 |
Gene (mouse) | Bcl6 |
Gene synonyms (mouse) | Bcl-6 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | BCL6.H12CORE.0.PSM.A |
Gene (human) | BCL6 (GeneCards) |
Gene synonyms (human) | BCL5, LAZ3, ZBTB27, ZNF51 |
Gene (mouse) | Bcl6 |
Gene synonyms (mouse) | Bcl-6 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 16 |
Consensus | nhGCTTTCKAGGAAYn |
GC content | 44.37% |
Information content (bits; total / per base) | 20.273 / 1.267 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 7198 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 10 (67) | 0.794 | 0.933 | 0.745 | 0.928 | 0.762 | 0.931 | 3.026 | 5.63 | 116.824 | 680.959 |
Mouse | 15 (93) | 0.816 | 0.97 | 0.745 | 0.929 | 0.801 | 0.964 | 3.076 | 4.837 | 101.585 | 213.244 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 2 experiments | median | 1.0 | 1.0 | 0.973 | 0.974 | 0.82 | 0.847 |
best | 1.0 | 1.0 | 0.998 | 0.998 | 0.896 | 0.908 | |
Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 0.998 | 0.998 | 0.896 | 0.908 |
best | 1.0 | 1.0 | 0.998 | 0.998 | 0.896 | 0.908 | |
Non-Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 0.948 | 0.949 | 0.743 | 0.785 |
best | 1.0 | 1.0 | 0.948 | 0.949 | 0.743 | 0.785 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 10.132 | 3.449 | 0.406 | 0.257 |
TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
TF class | C2H2 zinc finger factors {2.3} (TFClass) |
TF family | More than 3 adjacent zinc fingers {2.3.3} (TFClass) |
TF subfamily | BCL6 {2.3.3.22} (TFClass) |
TFClass ID | TFClass: 2.3.3.22.2 |
HGNC | HGNC:1001 |
MGI | MGI:107187 |
EntrezGene (human) | GeneID:604 (SSTAR profile) |
EntrezGene (mouse) | GeneID:12053 (SSTAR profile) |
UniProt ID (human) | BCL6_HUMAN |
UniProt ID (mouse) | BCL6_MOUSE |
UniProt AC (human) | P41182 (TFClass) |
UniProt AC (mouse) | P41183 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 10 human, 15 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 1 |
PCM | BCL6.H12CORE.0.PSM.A.pcm |
PWM | BCL6.H12CORE.0.PSM.A.pwm |
PFM | BCL6.H12CORE.0.PSM.A.pfm |
Alignment | BCL6.H12CORE.0.PSM.A.words.tsv |
Threshold to P-value map | BCL6.H12CORE.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | BCL6.H12CORE.0.PSM.A_jaspar_format.txt |
MEME format | BCL6.H12CORE.0.PSM.A_meme_format.meme |
Transfac format | BCL6.H12CORE.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2234.5 | 1536.5 | 1739.5 | 1687.5 |
02 | 913.25 | 2029.25 | 790.25 | 3465.25 |
03 | 850.0 | 142.0 | 5814.0 | 392.0 |
04 | 116.0 | 6848.0 | 82.0 | 152.0 |
05 | 383.0 | 103.0 | 37.0 | 6675.0 |
06 | 269.0 | 376.0 | 277.0 | 6276.0 |
07 | 4.0 | 2.0 | 1.0 | 7191.0 |
08 | 0.0 | 7189.0 | 0.0 | 9.0 |
09 | 18.0 | 381.0 | 4399.0 | 2400.0 |
10 | 7168.0 | 7.0 | 7.0 | 16.0 |
11 | 54.0 | 1.0 | 7137.0 | 6.0 |
12 | 9.0 | 11.0 | 7149.0 | 29.0 |
13 | 6900.0 | 30.0 | 173.0 | 95.0 |
14 | 6920.0 | 24.0 | 40.0 | 214.0 |
15 | 1359.0 | 1552.0 | 182.0 | 4105.0 |
16 | 1515.75 | 1347.75 | 1693.75 | 2640.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.31 | 0.213 | 0.242 | 0.234 |
02 | 0.127 | 0.282 | 0.11 | 0.481 |
03 | 0.118 | 0.02 | 0.808 | 0.054 |
04 | 0.016 | 0.951 | 0.011 | 0.021 |
05 | 0.053 | 0.014 | 0.005 | 0.927 |
06 | 0.037 | 0.052 | 0.038 | 0.872 |
07 | 0.001 | 0.0 | 0.0 | 0.999 |
08 | 0.0 | 0.999 | 0.0 | 0.001 |
09 | 0.003 | 0.053 | 0.611 | 0.333 |
10 | 0.996 | 0.001 | 0.001 | 0.002 |
11 | 0.008 | 0.0 | 0.992 | 0.001 |
12 | 0.001 | 0.002 | 0.993 | 0.004 |
13 | 0.959 | 0.004 | 0.024 | 0.013 |
14 | 0.961 | 0.003 | 0.006 | 0.03 |
15 | 0.189 | 0.216 | 0.025 | 0.57 |
16 | 0.211 | 0.187 | 0.235 | 0.367 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.216 | -0.158 | -0.034 | -0.064 |
02 | -0.677 | 0.12 | -0.821 | 0.655 |
03 | -0.749 | -2.525 | 1.172 | -1.52 |
04 | -2.724 | 1.336 | -3.063 | -2.458 |
05 | -1.543 | -2.84 | -3.827 | 1.31 |
06 | -1.894 | -1.561 | -1.864 | 1.248 |
07 | -5.669 | -6.057 | -6.327 | 1.384 |
08 | -6.699 | 1.384 | -6.699 | -5.079 |
09 | -4.49 | -1.548 | 0.893 | 0.288 |
10 | 1.381 | -5.275 | -5.275 | -4.594 |
11 | -3.467 | -6.327 | 1.377 | -5.39 |
12 | -5.079 | -4.915 | 1.379 | -4.055 |
13 | 1.343 | -4.024 | -2.33 | -2.92 |
14 | 1.346 | -4.23 | -3.754 | -2.12 |
15 | -0.28 | -0.148 | -2.28 | 0.824 |
16 | -0.171 | -0.289 | -0.06 | 0.383 |
P-value | Threshold |
---|---|
0.001 | -2.03654 |
0.0005 | -0.26699 |
0.0001 | 3.44896 |