BARH2.H12INVITRO.2.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BARH2.H12INVITRO.2.S.C
Gene (human)	BARHL2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Barhl2
Gene synonyms (mouse)	Barh1, Mbh1
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	C

Motif length	14
Consensus	nvRhCGTTTARYvn
GC content	44.3%
Information content (bits; total / per base)	12.927 / 0.923
Data sources	HT-SELEX
Aligned words	8430

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.958	0.933	0.937	0.902	0.905	0.866
Overall, 8 experiments	best	0.996	0.994	0.99	0.985	0.975	0.966
Methyl HT-SELEX, 2 experiments	median	0.967	0.945	0.955	0.928	0.933	0.902
Methyl HT-SELEX, 2 experiments	best	0.983	0.971	0.975	0.959	0.958	0.938
Non-Methyl HT-SELEX, 6 experiments	median	0.958	0.933	0.931	0.899	0.862	0.835
Non-Methyl HT-SELEX, 6 experiments	best	0.996	0.994	0.99	0.985	0.975	0.966

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	BARHL {3.1.2.1} (TFClass)
TFClass ID	TFClass: 3.1.2.1.2
HGNC	HGNC:954
MGI	MGI:1859314
EntrezGene (human)	GeneID:343472 (SSTAR profile)
EntrezGene (mouse)	GeneID:104382 (SSTAR profile)
UniProt ID (human)	BARH2_HUMAN
UniProt ID (mouse)	BARH2_MOUSE
UniProt AC (human)	Q9NY43 (TFClass)
UniProt AC (mouse)	Q8VIB5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	6
Methyl-HT-SELEX	2

PCM	BARH2.H12INVITRO.2.S.C.pcm
PWM	BARH2.H12INVITRO.2.S.C.pwm
PFM	BARH2.H12INVITRO.2.S.C.pfm
Alignment	BARH2.H12INVITRO.2.S.C.words.tsv
Threshold to P-value map	BARH2.H12INVITRO.2.S.C.thr
Motif in other formats
JASPAR format	BARH2.H12INVITRO.2.S.C_jaspar_format.txt
MEME format	BARH2.H12INVITRO.2.S.C_meme_format.meme
Transfac format	BARH2.H12INVITRO.2.S.C_transfac_format.txt
Homer format	BARH2.H12INVITRO.2.S.C_homer_format_0.001.txt BARH2.H12INVITRO.2.S.C_homer_format_0.0005.txt BARH2.H12INVITRO.2.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1806.5	1784.5	2007.5	2831.5
02	3067.25	1862.25	2367.25	1133.25
03	6415.0	429.0	1194.0	392.0
04	1613.0	4009.0	1397.0	1411.0
05	13.0	8335.0	2.0	80.0
06	2248.0	16.0	6164.0	2.0
07	2234.0	12.0	0.0	6184.0
08	0.0	0.0	0.0	8430.0
09	0.0	0.0	0.0	8430.0
10	8430.0	0.0	0.0	0.0
11	1256.0	138.0	6405.0	631.0
12	269.0	4563.0	1394.0	2204.0
13	1489.75	1551.75	4294.75	1093.75
14	1981.5	2234.5	2120.5	2093.5

PFM

	A	C	G	T
01	0.214	0.212	0.238	0.336
02	0.364	0.221	0.281	0.134
03	0.761	0.051	0.142	0.047
04	0.191	0.476	0.166	0.167
05	0.002	0.989	0.0	0.009
06	0.267	0.002	0.731	0.0
07	0.265	0.001	0.0	0.734
08	0.0	0.0	0.0	1.0
09	0.0	0.0	0.0	1.0
10	1.0	0.0	0.0	0.0
11	0.149	0.016	0.76	0.075
12	0.032	0.541	0.165	0.261
13	0.177	0.184	0.509	0.13
14	0.235	0.265	0.252	0.248

PWM

	A	C	G	T
01	-0.154	-0.166	-0.049	0.295
02	0.375	-0.124	0.116	-0.619
03	1.112	-1.588	-0.567	-1.677
04	-0.267	0.643	-0.411	-0.401
05	-4.929	1.374	-6.205	-3.244
06	0.064	-4.75	1.073	-6.205
07	0.058	-4.997	-6.839	1.076
08	-6.839	-6.839	-6.839	1.385
09	-6.839	-6.839	-6.839	1.385
10	1.385	-6.839	-6.839	-6.839
11	-0.517	-2.711	1.111	-1.203
12	-2.051	0.772	-0.413	0.045
13	-0.346	-0.306	0.711	-0.655
14	-0.062	0.058	0.006	-0.007

Standard thresholds

P-value	Threshold
0.001	2.56706
0.0005	4.48611
0.0001	7.40641