BARH2.H12CORE.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BARH2.H12CORE.1.S.B
Gene (human)	BARHL2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Barhl2
Gene synonyms (mouse)	Barh1, Mbh1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	20
Consensus	nbhnWWWddbvbCRWTTARn
GC content	37.33%
Information content (bits; total / per base)	14.061 / 0.703
Data sources	HT-SELEX
Aligned words	8049

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.963	0.94	0.938	0.908	0.886	0.85
Overall, 8 experiments	best	0.996	0.994	0.987	0.983	0.931	0.924
Methyl HT-SELEX, 2 experiments	median	0.963	0.94	0.938	0.908	0.894	0.86
Methyl HT-SELEX, 2 experiments	best	0.963	0.941	0.942	0.912	0.899	0.865
Non-Methyl HT-SELEX, 6 experiments	median	0.959	0.935	0.936	0.903	0.854	0.835
Non-Methyl HT-SELEX, 6 experiments	best	0.996	0.994	0.987	0.983	0.931	0.924

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	BARHL {3.1.2.1} (TFClass)
TFClass ID	TFClass: 3.1.2.1.2
HGNC	HGNC:954
MGI	MGI:1859314
EntrezGene (human)	GeneID:343472 (SSTAR profile)
EntrezGene (mouse)	GeneID:104382 (SSTAR profile)
UniProt ID (human)	BARH2_HUMAN
UniProt ID (mouse)	BARH2_MOUSE
UniProt AC (human)	Q9NY43 (TFClass)
UniProt AC (mouse)	Q8VIB5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	6
Methyl-HT-SELEX	2

PCM	BARH2.H12CORE.1.S.B.pcm
PWM	BARH2.H12CORE.1.S.B.pwm
PFM	BARH2.H12CORE.1.S.B.pfm
Alignment	BARH2.H12CORE.1.S.B.words.tsv
Threshold to P-value map	BARH2.H12CORE.1.S.B.thr
Motif in other formats
JASPAR format	BARH2.H12CORE.1.S.B_jaspar_format.txt
MEME format	BARH2.H12CORE.1.S.B_meme_format.meme
Transfac format	BARH2.H12CORE.1.S.B_transfac_format.txt
Homer format	BARH2.H12CORE.1.S.B_homer_format_0.001.txt BARH2.H12CORE.1.S.B_homer_format_0.0005.txt BARH2.H12CORE.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1981.0	2305.0	1851.0	1912.0
02	1469.25	3312.25	1618.25	1649.25
03	1363.0	3989.0	1195.0	1502.0
04	2536.0	1579.0	1258.0	2676.0
05	3303.0	471.0	92.0	4183.0
06	4391.0	20.0	38.0	3600.0
07	4347.0	100.0	186.0	3416.0
08	3926.0	429.0	1022.0	2672.0
09	1282.0	1025.0	3126.0	2616.0
10	621.0	1733.0	4656.0	1039.0
11	3742.0	619.0	3117.0	571.0
12	787.0	3337.0	1704.0	2221.0
13	16.0	7642.0	5.0	386.0
14	4878.0	254.0	2896.0	21.0
15	4777.0	387.0	2.0	2883.0
16	1.0	0.0	0.0	8048.0
17	80.0	8.0	1.0	7960.0
18	7985.0	0.0	34.0	30.0
19	1947.0	410.0	5159.0	533.0
20	1441.75	2384.75	2120.75	2101.75

PFM

	A	C	G	T
01	0.246	0.286	0.23	0.238
02	0.183	0.412	0.201	0.205
03	0.169	0.496	0.148	0.187
04	0.315	0.196	0.156	0.332
05	0.41	0.059	0.011	0.52
06	0.546	0.002	0.005	0.447
07	0.54	0.012	0.023	0.424
08	0.488	0.053	0.127	0.332
09	0.159	0.127	0.388	0.325
10	0.077	0.215	0.578	0.129
11	0.465	0.077	0.387	0.071
12	0.098	0.415	0.212	0.276
13	0.002	0.949	0.001	0.048
14	0.606	0.032	0.36	0.003
15	0.593	0.048	0.0	0.358
16	0.0	0.0	0.0	1.0
17	0.01	0.001	0.0	0.989
18	0.992	0.0	0.004	0.004
19	0.242	0.051	0.641	0.066
20	0.179	0.296	0.263	0.261

PWM

	A	C	G	T
01	-0.016	0.136	-0.083	-0.051
02	-0.314	0.498	-0.218	-0.199
03	-0.389	0.684	-0.52	-0.292
04	0.231	-0.242	-0.469	0.285
05	0.495	-1.449	-3.062	0.731
06	0.78	-4.506	-3.913	0.581
07	0.77	-2.981	-2.37	0.529
08	0.668	-1.541	-0.676	0.283
09	-0.45	-0.673	0.44	0.262
10	-1.173	-0.149	0.838	-0.66
11	0.62	-1.176	0.437	-1.257
12	-0.937	0.505	-0.166	0.099
13	-4.704	1.334	-5.627	-1.646
14	0.885	-2.062	0.364	-4.462
15	0.864	-1.644	-6.162	0.359
16	-6.43	-6.798	-6.798	1.385
17	-3.198	-5.281	-6.43	1.374
18	1.377	-6.798	-4.018	-4.135
19	-0.033	-1.586	0.941	-1.325
20	-0.333	0.17	0.052	0.043

Standard thresholds

P-value	Threshold
0.001	2.58311
0.0005	4.00901
0.0001	6.86491