BARH1.H12RSNP.1.S.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BARH1.H12RSNP.1.S.D
Gene (human)	BARHL1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Barhl1
Gene synonyms (mouse)	Bhx1, Mbh2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	18
Consensus	bvYTAAWYGnbnhhWWdn
GC content	37.03%
Information content (bits; total / per base)	11.906 / 0.661
Data sources	HT-SELEX
Aligned words	7323

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.932	0.898	0.894	0.841	0.852	0.801
Overall, 4 experiments	best	0.994	0.99	0.98	0.973	0.919	0.909
Methyl HT-SELEX, 1 experiments	median	0.93	0.885	0.908	0.859	0.868	0.82
Methyl HT-SELEX, 1 experiments	best	0.93	0.885	0.908	0.859	0.868	0.82
Non-Methyl HT-SELEX, 3 experiments	median	0.935	0.91	0.88	0.823	0.836	0.783
Non-Methyl HT-SELEX, 3 experiments	best	0.994	0.99	0.98	0.973	0.919	0.909

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	BARHL {3.1.2.1} (TFClass)
TFClass ID	TFClass: 3.1.2.1.1
HGNC	HGNC:953
MGI	MGI:1859288
EntrezGene (human)	GeneID:56751 (SSTAR profile)
EntrezGene (mouse)	GeneID:54422 (SSTAR profile)
UniProt ID (human)	BARH1_HUMAN
UniProt ID (mouse)	BARH1_MOUSE
UniProt AC (human)	Q9BZE3 (TFClass)
UniProt AC (mouse)	P63157 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	BARH1.H12RSNP.1.S.D.pcm
PWM	BARH1.H12RSNP.1.S.D.pwm
PFM	BARH1.H12RSNP.1.S.D.pfm
Alignment	BARH1.H12RSNP.1.S.D.words.tsv
Threshold to P-value map	BARH1.H12RSNP.1.S.D.thr
Motif in other formats
JASPAR format	BARH1.H12RSNP.1.S.D_jaspar_format.txt
MEME format	BARH1.H12RSNP.1.S.D_meme_format.meme
Transfac format	BARH1.H12RSNP.1.S.D_transfac_format.txt
Homer format	BARH1.H12RSNP.1.S.D_homer_format_0.001.txt BARH1.H12RSNP.1.S.D_homer_format_0.0005.txt BARH1.H12RSNP.1.S.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1239.5	2953.5	1855.5	1274.5
02	1759.0	2051.0	2833.0	680.0
03	636.0	4317.0	511.0	1859.0
04	5.0	17.0	1.0	7300.0
05	7208.0	0.0	1.0	114.0
06	7323.0	0.0	0.0	0.0
07	3132.0	7.0	440.0	3744.0
08	43.0	3604.0	457.0	3219.0
09	837.0	32.0	6388.0	66.0
10	1466.0	2231.0	2502.0	1124.0
11	762.0	2754.0	928.0	2879.0
12	1317.0	2862.0	1773.0	1371.0
13	2255.0	2475.0	674.0	1919.0
14	2007.0	1008.0	378.0	3930.0
15	3667.0	430.0	158.0	3068.0
16	4539.0	313.0	163.0	2308.0
17	3321.5	627.5	734.5	2639.5
18	1959.5	1890.5	1440.5	2032.5

PFM

	A	C	G	T
01	0.169	0.403	0.253	0.174
02	0.24	0.28	0.387	0.093
03	0.087	0.59	0.07	0.254
04	0.001	0.002	0.0	0.997
05	0.984	0.0	0.0	0.016
06	1.0	0.0	0.0	0.0
07	0.428	0.001	0.06	0.511
08	0.006	0.492	0.062	0.44
09	0.114	0.004	0.872	0.009
10	0.2	0.305	0.342	0.153
11	0.104	0.376	0.127	0.393
12	0.18	0.391	0.242	0.187
13	0.308	0.338	0.092	0.262
14	0.274	0.138	0.052	0.537
15	0.501	0.059	0.022	0.419
16	0.62	0.043	0.022	0.315
17	0.454	0.086	0.1	0.36
18	0.268	0.258	0.197	0.278

PWM

	A	C	G	T
01	-0.389	0.478	0.013	-0.362
02	-0.04	0.113	0.436	-0.988
03	-1.055	0.857	-1.273	0.015
04	-5.536	-4.557	-6.343	1.382
05	1.37	-6.714	-6.343	-2.758
06	1.385	-6.714	-6.714	-6.714
07	0.536	-5.292	-1.422	0.715
08	-3.702	0.677	-1.384	0.564
09	-0.781	-3.981	1.249	-3.291
10	-0.222	0.198	0.312	-0.487
11	-0.875	0.408	-0.678	0.452
12	-0.329	0.446	-0.032	-0.289
13	0.208	0.301	-0.997	0.047
14	0.092	-0.596	-1.573	0.763
15	0.694	-1.445	-2.437	0.516
16	0.907	-1.76	-2.406	0.231
17	0.595	-1.068	-0.911	0.365
18	0.068	0.032	-0.239	0.104

Standard thresholds

P-value	Threshold
0.001	4.02836
0.0005	5.22431
0.0001	7.41881