BARH1.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BARH1.H12INVITRO.0.SM.B
Gene (human)	BARHL1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Barhl1
Gene synonyms (mouse)	Bhx1, Mbh2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	nnvhTAAWYRnn
GC content	41.54%
Information content (bits; total / per base)	8.637 / 0.72
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9929

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.933	0.892	0.912	0.865	0.877	0.829
Overall, 4 experiments	best	0.982	0.971	0.967	0.95	0.914	0.895
Methyl HT-SELEX, 1 experiments	median	0.94	0.904	0.919	0.877	0.887	0.841
Methyl HT-SELEX, 1 experiments	best	0.94	0.904	0.919	0.877	0.887	0.841
Non-Methyl HT-SELEX, 3 experiments	median	0.926	0.88	0.904	0.854	0.867	0.817
Non-Methyl HT-SELEX, 3 experiments	best	0.982	0.971	0.967	0.95	0.914	0.895

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	BARHL {3.1.2.1} (TFClass)
TFClass ID	TFClass: 3.1.2.1.1
HGNC	HGNC:953
MGI	MGI:1859288
EntrezGene (human)	GeneID:56751 (SSTAR profile)
EntrezGene (mouse)	GeneID:54422 (SSTAR profile)
UniProt ID (human)	BARH1_HUMAN
UniProt ID (mouse)	BARH1_MOUSE
UniProt AC (human)	Q9BZE3 (TFClass)
UniProt AC (mouse)	P63157 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	BARH1.H12INVITRO.0.SM.B.pcm
PWM	BARH1.H12INVITRO.0.SM.B.pwm
PFM	BARH1.H12INVITRO.0.SM.B.pfm
Alignment	BARH1.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	BARH1.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	BARH1.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	BARH1.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	BARH1.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	BARH1.H12INVITRO.0.SM.B_homer_format_0.001.txt BARH1.H12INVITRO.0.SM.B_homer_format_0.0005.txt BARH1.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2059.0	2680.0	2924.0	2266.0
02	1760.25	3423.25	2806.25	1939.25
03	2216.0	2619.0	3914.0	1180.0
04	1015.0	4814.0	881.0	3219.0
05	3.0	68.0	5.0	9853.0
06	9920.0	1.0	3.0	5.0
07	9929.0	0.0	0.0	0.0
08	3514.0	21.0	789.0	5605.0
09	171.0	3923.0	1307.0	4528.0
10	1645.0	305.0	7609.0	370.0
11	1729.0	3084.0	3330.0	1786.0
12	1680.75	2873.75	2118.75	3255.75

PFM

	A	C	G	T
01	0.207	0.27	0.294	0.228
02	0.177	0.345	0.283	0.195
03	0.223	0.264	0.394	0.119
04	0.102	0.485	0.089	0.324
05	0.0	0.007	0.001	0.992
06	0.999	0.0	0.0	0.001
07	1.0	0.0	0.0	0.0
08	0.354	0.002	0.079	0.565
09	0.017	0.395	0.132	0.456
10	0.166	0.031	0.766	0.037
11	0.174	0.311	0.335	0.18
12	0.169	0.289	0.213	0.328

PWM

	A	C	G	T
01	-0.187	0.077	0.164	-0.091
02	-0.343	0.321	0.123	-0.247
03	-0.113	0.054	0.455	-0.743
04	-0.893	0.662	-1.034	0.26
05	-6.15	-3.565	-5.83	1.378
06	1.385	-6.624	-6.15	-5.83
07	1.386	-6.985	-6.985	-6.985
08	0.347	-4.669	-1.144	0.814
09	-2.663	0.457	-0.641	0.601
10	-0.411	-2.09	1.12	-1.898
11	-0.361	0.217	0.294	-0.329
12	-0.389	0.146	-0.158	0.271

Standard thresholds

P-value	Threshold
0.001	5.44531
0.0005	6.13601
0.0001	7.257885