BACH2.H12INVIVO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BACH2.H12INVIVO.1.SM.B
Gene (human)	BACH2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Bach2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	14
Consensus	vTGASTCATbnhdn
GC content	40.33%
Information content (bits; total / per base)	15.143 / 1.082
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.82	0.864	0.73	0.78	0.795	0.841	2.773	3.019	147.114	191.745
Mouse	4 (25)	0.846	0.885	0.756	0.811	0.811	0.85	2.794	3.185	183.796	265.745

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.999	0.999	0.949	0.953	0.821	0.846
Overall, 2 experiments	best	1.0	1.0	1.0	1.0	0.932	0.941
Methyl HT-SELEX, 1 experiments	median	0.998	0.997	0.898	0.906	0.71	0.751
Methyl HT-SELEX, 1 experiments	best	0.998	0.997	0.898	0.906	0.71	0.751
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	1.0	0.932	0.941
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	1.0	0.932	0.941

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.991	0.92	0.739	0.39

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.6
HGNC	HGNC:14078
MGI	MGI:894679
EntrezGene (human)	GeneID:60468 (SSTAR profile)
EntrezGene (mouse)	GeneID:12014 (SSTAR profile)
UniProt ID (human)	BACH2_HUMAN
UniProt ID (mouse)	BACH2_MOUSE
UniProt AC (human)	Q9BYV9 (TFClass)
UniProt AC (mouse)	P97303 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	BACH2.H12INVIVO.1.SM.B.pcm
PWM	BACH2.H12INVIVO.1.SM.B.pwm
PFM	BACH2.H12INVIVO.1.SM.B.pfm
Alignment	BACH2.H12INVIVO.1.SM.B.words.tsv
Threshold to P-value map	BACH2.H12INVIVO.1.SM.B.thr
Motif in other formats
JASPAR format	BACH2.H12INVIVO.1.SM.B_jaspar_format.txt
MEME format	BACH2.H12INVIVO.1.SM.B_meme_format.meme
Transfac format	BACH2.H12INVIVO.1.SM.B_transfac_format.txt
Homer format	BACH2.H12INVIVO.1.SM.B_homer_format_0.001.txt BACH2.H12INVIVO.1.SM.B_homer_format_0.0005.txt BACH2.H12INVIVO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	4303.25	1804.25	2099.25	1791.25
02	141.25	334.25	126.25	9396.25
03	88.0	29.0	9736.0	145.0
04	9920.0	39.0	27.0	12.0
05	1.0	5434.0	4559.0	4.0
06	2.0	0.0	1.0	9995.0
07	0.0	9996.0	0.0	2.0
08	9882.0	17.0	95.0	4.0
09	34.0	236.0	109.0	9619.0
10	807.0	2991.0	5269.0	931.0
11	3354.0	2585.0	2796.0	1263.0
12	2126.0	1437.0	873.0	5562.0
13	3619.0	1012.0	1096.0	4271.0
14	2654.75	2052.75	1698.75	3591.75

PFM

	A	C	G	T
01	0.43	0.18	0.21	0.179
02	0.014	0.033	0.013	0.94
03	0.009	0.003	0.974	0.015
04	0.992	0.004	0.003	0.001
05	0.0	0.544	0.456	0.0
06	0.0	0.0	0.0	1.0
07	0.0	1.0	0.0	0.0
08	0.988	0.002	0.01	0.0
09	0.003	0.024	0.011	0.962
10	0.081	0.299	0.527	0.093
11	0.335	0.259	0.28	0.126
12	0.213	0.144	0.087	0.556
13	0.362	0.101	0.11	0.427
14	0.266	0.205	0.17	0.359

PWM

	A	C	G	T
01	0.543	-0.326	-0.174	-0.333
02	-2.858	-2.006	-2.968	1.324
03	-3.322	-4.381	1.359	-2.832
04	1.378	-4.104	-4.447	-5.164
05	-6.63	0.776	0.601	-5.984
06	-6.366	-6.991	-6.63	1.385
07	-6.991	1.385	-6.991	-6.366
08	1.374	-4.865	-3.247	-5.984
09	-4.233	-2.351	-3.113	1.347
10	-1.129	0.179	0.745	-0.986
11	0.294	0.034	0.112	-0.682
12	-0.162	-0.553	-1.05	0.799
13	0.37	-0.903	-0.823	0.535
14	0.06	-0.197	-0.386	0.362

Standard thresholds

P-value	Threshold
0.001	1.25246
0.0005	2.85506
0.0001	6.08416