BACH2.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BACH2.H12INVIVO.0.P.B
Gene (human)	BACH2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Bach2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	WGCTGASTCAb
GC content	48.35%
Information content (bits; total / per base)	12.9 / 1.173
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.907	0.936	0.854	0.903	0.902	0.93	4.349	4.893	246.0	311.092
Mouse	4 (25)	0.908	0.944	0.858	0.915	0.898	0.936	4.072	5.323	292.796	419.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.976	0.963	0.931	0.919	0.811	0.821
Overall, 2 experiments	best	0.993	0.989	0.986	0.979	0.914	0.914
Methyl HT-SELEX, 1 experiments	median	0.959	0.937	0.875	0.859	0.708	0.729
Methyl HT-SELEX, 1 experiments	best	0.959	0.937	0.875	0.859	0.708	0.729
Non-Methyl HT-SELEX, 1 experiments	median	0.993	0.989	0.986	0.979	0.914	0.914
Non-Methyl HT-SELEX, 1 experiments	best	0.993	0.989	0.986	0.979	0.914	0.914

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.771	0.584	0.868	0.638

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.6
HGNC	HGNC:14078
MGI	MGI:894679
EntrezGene (human)	GeneID:60468 (SSTAR profile)
EntrezGene (mouse)	GeneID:12014 (SSTAR profile)
UniProt ID (human)	BACH2_HUMAN
UniProt ID (mouse)	BACH2_MOUSE
UniProt AC (human)	Q9BYV9 (TFClass)
UniProt AC (mouse)	P97303 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	BACH2.H12INVIVO.0.P.B.pcm
PWM	BACH2.H12INVIVO.0.P.B.pwm
PFM	BACH2.H12INVIVO.0.P.B.pfm
Alignment	BACH2.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	BACH2.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	BACH2.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	BACH2.H12INVIVO.0.P.B_meme_format.meme
Transfac format	BACH2.H12INVIVO.0.P.B_transfac_format.txt
Homer format	BACH2.H12INVIVO.0.P.B_homer_format_0.001.txt BACH2.H12INVIVO.0.P.B_homer_format_0.0005.txt BACH2.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	170.0	80.0	76.0	674.0
02	25.0	91.0	844.0	40.0
03	86.0	883.0	15.0	16.0
04	75.0	35.0	8.0	882.0
05	40.0	36.0	831.0	93.0
06	845.0	26.0	27.0	102.0
07	66.0	195.0	703.0	36.0
08	10.0	9.0	5.0	976.0
09	59.0	919.0	12.0	10.0
10	981.0	9.0	6.0	4.0
11	51.0	312.0	197.0	440.0

PFM

	A	C	G	T
01	0.17	0.08	0.076	0.674
02	0.025	0.091	0.844	0.04
03	0.086	0.883	0.015	0.016
04	0.075	0.035	0.008	0.882
05	0.04	0.036	0.831	0.093
06	0.845	0.026	0.027	0.102
07	0.066	0.195	0.703	0.036
08	0.01	0.009	0.005	0.976
09	0.059	0.919	0.012	0.01
10	0.981	0.009	0.006	0.004
11	0.051	0.312	0.197	0.44

PWM

	A	C	G	T
01	-0.382	-1.125	-1.175	0.987
02	-2.243	-0.999	1.212	-1.797
03	-1.054	1.257	-2.711	-2.653
04	-1.188	-1.925	-3.253	1.256
05	-1.797	-1.898	1.196	-0.977
06	1.213	-2.206	-2.171	-0.887
07	-1.313	-0.247	1.029	-1.898
08	-3.066	-3.156	-3.622	1.357
09	-1.422	1.297	-2.909	-3.066
10	1.362	-3.156	-3.484	-3.783
11	-1.563	0.22	-0.236	0.562

Standard thresholds

P-value	Threshold
0.001	3.8758
0.0005	4.905585
0.0001	7.048445