BACH2.H12INVITRO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BACH2.H12INVITRO.1.SM.B
Gene (human)	BACH2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Bach2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	17
Consensus	nvATGAGTCATSnWWhn
GC content	42.9%
Information content (bits; total / per base)	18.94 / 1.114
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.794	0.841	0.716	0.77	0.768	0.818	2.559	2.831	99.921	137.161
Mouse	4 (25)	0.824	0.861	0.743	0.798	0.781	0.82	2.614	2.969	147.143	194.523

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	1.0	0.999	0.954	0.957	0.829	0.852
Overall, 2 experiments	best	1.0	1.0	1.0	1.0	0.937	0.946
Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.907	0.915	0.721	0.759
Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.907	0.915	0.721	0.759
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	1.0	0.937	0.946
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	1.0	0.937	0.946

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.954	0.905	0.853	0.619

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.6
HGNC	HGNC:14078
MGI	MGI:894679
EntrezGene (human)	GeneID:60468 (SSTAR profile)
EntrezGene (mouse)	GeneID:12014 (SSTAR profile)
UniProt ID (human)	BACH2_HUMAN
UniProt ID (mouse)	BACH2_MOUSE
UniProt AC (human)	Q9BYV9 (TFClass)
UniProt AC (mouse)	P97303 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	BACH2.H12INVITRO.1.SM.B.pcm
PWM	BACH2.H12INVITRO.1.SM.B.pwm
PFM	BACH2.H12INVITRO.1.SM.B.pfm
Alignment	BACH2.H12INVITRO.1.SM.B.words.tsv
Threshold to P-value map	BACH2.H12INVITRO.1.SM.B.thr
Motif in other formats
JASPAR format	BACH2.H12INVITRO.1.SM.B_jaspar_format.txt
MEME format	BACH2.H12INVITRO.1.SM.B_meme_format.meme
Transfac format	BACH2.H12INVITRO.1.SM.B_transfac_format.txt
Homer format	BACH2.H12INVITRO.1.SM.B_homer_format_0.001.txt BACH2.H12INVITRO.1.SM.B_homer_format_0.0005.txt BACH2.H12INVITRO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1249.25	2735.25	3196.25	2816.25
02	1027.5	5295.5	2859.5	814.5
03	8963.0	131.0	862.0	41.0
04	4.0	6.0	3.0	9984.0
05	1.0	0.0	9989.0	7.0
06	9985.0	12.0	0.0	0.0
07	0.0	4399.0	5598.0	0.0
08	0.0	2.0	1.0	9994.0
09	3.0	9991.0	1.0	2.0
10	9991.0	0.0	5.0	1.0
11	7.0	597.0	53.0	9340.0
12	390.0	1705.0	7490.0	412.0
13	2501.0	2979.0	3100.0	1417.0
14	779.0	755.0	451.0	8012.0
15	2710.0	708.0	827.0	5752.0
16	2440.75	1912.75	1556.75	4086.75
17	1979.0	2640.0	3048.0	2330.0

PFM

	A	C	G	T
01	0.125	0.274	0.32	0.282
02	0.103	0.53	0.286	0.081
03	0.897	0.013	0.086	0.004
04	0.0	0.001	0.0	0.999
05	0.0	0.0	0.999	0.001
06	0.999	0.001	0.0	0.0
07	0.0	0.44	0.56	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.999	0.0	0.0
10	0.999	0.0	0.001	0.0
11	0.001	0.06	0.005	0.934
12	0.039	0.171	0.749	0.041
13	0.25	0.298	0.31	0.142
14	0.078	0.076	0.045	0.801
15	0.271	0.071	0.083	0.575
16	0.244	0.191	0.156	0.409
17	0.198	0.264	0.305	0.233

PWM

	A	C	G	T
01	-0.693	0.09	0.246	0.119
02	-0.888	0.75	0.135	-1.119
03	1.276	-2.932	-1.063	-4.056
04	-5.984	-5.708	-6.156	1.384
05	-6.63	-6.991	1.385	-5.594
06	1.384	-5.164	-6.991	-6.991
07	-6.991	0.565	0.806	-6.991
08	-6.991	-6.365	-6.63	1.385
09	-6.156	1.385	-6.63	-6.365
10	1.385	-6.991	-5.836	-6.63
11	-5.594	-1.429	-3.812	1.318
12	-1.853	-0.382	1.097	-1.798
13	0.001	0.175	0.215	-0.567
14	-1.164	-1.195	-1.708	1.164
15	0.081	-1.259	-1.104	0.833
16	-0.024	-0.267	-0.473	0.491
17	-0.233	0.055	0.198	-0.07

Standard thresholds

P-value	Threshold
0.001	-3.25759
0.0005	-1.14119
0.0001	3.11781