BACH2.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BACH2.H12INVITRO.0.P.B
Gene (human)	BACH2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Bach2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	SMTGAGTCAbn
GC content	51.55%
Information content (bits; total / per base)	12.559 / 1.142
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.873	0.91	0.811	0.86	0.879	0.917	4.006	4.39	224.721	279.0
Mouse	4 (25)	0.888	0.919	0.836	0.883	0.886	0.92	3.957	4.704	270.745	379.056

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.99	0.981	0.943	0.939	0.821	0.838
Overall, 2 experiments	best	0.997	0.993	0.994	0.99	0.927	0.931
Methyl HT-SELEX, 1 experiments	median	0.984	0.969	0.892	0.889	0.714	0.745
Methyl HT-SELEX, 1 experiments	best	0.984	0.969	0.892	0.889	0.714	0.745
Non-Methyl HT-SELEX, 1 experiments	median	0.997	0.993	0.994	0.99	0.927	0.931
Non-Methyl HT-SELEX, 1 experiments	best	0.997	0.993	0.994	0.99	0.927	0.931

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.892	0.788	0.87	0.676

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.6
HGNC	HGNC:14078
MGI	MGI:894679
EntrezGene (human)	GeneID:60468 (SSTAR profile)
EntrezGene (mouse)	GeneID:12014 (SSTAR profile)
UniProt ID (human)	BACH2_HUMAN
UniProt ID (mouse)	BACH2_MOUSE
UniProt AC (human)	Q9BYV9 (TFClass)
UniProt AC (mouse)	P97303 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	BACH2.H12INVITRO.0.P.B.pcm
PWM	BACH2.H12INVITRO.0.P.B.pwm
PFM	BACH2.H12INVITRO.0.P.B.pfm
Alignment	BACH2.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	BACH2.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	BACH2.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	BACH2.H12INVITRO.0.P.B_meme_format.meme
Transfac format	BACH2.H12INVITRO.0.P.B_transfac_format.txt
Homer format	BACH2.H12INVITRO.0.P.B_homer_format_0.001.txt BACH2.H12INVITRO.0.P.B_homer_format_0.0005.txt BACH2.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	84.0	139.0	685.0	92.0
02	153.0	750.0	66.0	31.0
03	54.0	18.0	4.0	924.0
04	16.0	17.0	891.0	76.0
05	894.0	12.0	14.0	80.0
06	57.0	2.0	913.0	28.0
07	8.0	15.0	22.0	955.0
08	67.0	908.0	22.0	3.0
09	983.0	6.0	8.0	3.0
10	44.0	253.0	317.0	386.0
11	166.0	379.0	230.0	225.0

PFM

	A	C	G	T
01	0.084	0.139	0.685	0.092
02	0.153	0.75	0.066	0.031
03	0.054	0.018	0.004	0.924
04	0.016	0.017	0.891	0.076
05	0.894	0.012	0.014	0.08
06	0.057	0.002	0.913	0.028
07	0.008	0.015	0.022	0.955
08	0.067	0.908	0.022	0.003
09	0.983	0.006	0.008	0.003
10	0.044	0.253	0.317	0.386
11	0.166	0.379	0.23	0.225

PWM

	A	C	G	T
01	-1.077	-0.582	1.004	-0.988
02	-0.487	1.094	-1.313	-2.04
03	-1.508	-2.546	-3.783	1.302
04	-2.653	-2.598	1.266	-1.175
05	1.269	-2.909	-2.773	-1.125
06	-1.455	-4.213	1.29	-2.136
07	-3.253	-2.711	-2.362	1.335
08	-1.298	1.285	-2.362	-3.975
09	1.364	-3.484	-3.253	-3.975
10	-1.706	0.012	0.236	0.432
11	-0.406	0.414	-0.083	-0.105

Standard thresholds

P-value	Threshold
0.001	3.93561
0.0005	4.95762
0.0001	7.109375