BACH2.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BACH2.H12CORE.0.P.B
Gene (human)	BACH2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Bach2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	SMTGAGTCAbv
GC content	52.93%
Information content (bits; total / per base)	12.621 / 1.147
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.877	0.913	0.814	0.864	0.88	0.914	3.961	4.392	224.276	279.509
Mouse	4 (25)	0.896	0.927	0.841	0.889	0.894	0.928	3.961	4.735	278.432	395.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.988	0.976	0.94	0.934	0.818	0.834
Overall, 2 experiments	best	0.995	0.991	0.993	0.987	0.925	0.927
Methyl HT-SELEX, 1 experiments	median	0.98	0.962	0.888	0.882	0.711	0.74
Methyl HT-SELEX, 1 experiments	best	0.98	0.962	0.888	0.882	0.711	0.74
Non-Methyl HT-SELEX, 1 experiments	median	0.995	0.991	0.993	0.987	0.925	0.927
Non-Methyl HT-SELEX, 1 experiments	best	0.995	0.991	0.993	0.987	0.925	0.927

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.896	0.792	0.88	0.771

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.6
HGNC	HGNC:14078
MGI	MGI:894679
EntrezGene (human)	GeneID:60468 (SSTAR profile)
EntrezGene (mouse)	GeneID:12014 (SSTAR profile)
UniProt ID (human)	BACH2_HUMAN
UniProt ID (mouse)	BACH2_MOUSE
UniProt AC (human)	Q9BYV9 (TFClass)
UniProt AC (mouse)	P97303 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	BACH2.H12CORE.0.P.B.pcm
PWM	BACH2.H12CORE.0.P.B.pwm
PFM	BACH2.H12CORE.0.P.B.pfm
Alignment	BACH2.H12CORE.0.P.B.words.tsv
Threshold to P-value map	BACH2.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	BACH2.H12CORE.0.P.B_jaspar_format.txt
MEME format	BACH2.H12CORE.0.P.B_meme_format.meme
Transfac format	BACH2.H12CORE.0.P.B_transfac_format.txt
Homer format	BACH2.H12CORE.0.P.B_homer_format_0.001.txt BACH2.H12CORE.0.P.B_homer_format_0.0005.txt BACH2.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	64.0	137.0	733.0	66.0
02	106.0	800.0	60.0	34.0
03	76.0	33.0	7.0	884.0
04	36.0	30.0	829.0	105.0
05	853.0	16.0	14.0	117.0
06	25.0	7.0	949.0	19.0
07	10.0	22.0	10.0	958.0
08	33.0	952.0	10.0	5.0
09	975.0	9.0	1.0	15.0
10	40.0	246.0	304.0	410.0
11	182.0	393.0	260.0	165.0

PFM

	A	C	G	T
01	0.064	0.137	0.733	0.066
02	0.106	0.8	0.06	0.034
03	0.076	0.033	0.007	0.884
04	0.036	0.03	0.829	0.105
05	0.853	0.016	0.014	0.117
06	0.025	0.007	0.949	0.019
07	0.01	0.022	0.01	0.958
08	0.033	0.952	0.01	0.005
09	0.975	0.009	0.001	0.015
10	0.04	0.246	0.304	0.41
11	0.182	0.393	0.26	0.165

PWM

	A	C	G	T
01	-1.343	-0.596	1.071	-1.313
02	-0.849	1.158	-1.406	-1.952
03	-1.175	-1.981	-3.362	1.258
04	-1.898	-2.071	1.194	-0.858
05	1.222	-2.653	-2.773	-0.752
06	-2.243	-3.362	1.329	-2.497
07	-3.066	-2.362	-3.066	1.338
08	-1.981	1.332	-3.066	-3.622
09	1.356	-3.156	-4.525	-2.711
10	-1.797	-0.016	0.194	0.492
11	-0.315	0.45	0.039	-0.412

Standard thresholds

P-value	Threshold
0.001	3.92005
0.0005	4.964935
0.0001	7.082165