Motif | ATOH1.H12RSNP.1.SM.B |
Gene (human) | ATOH1 (GeneCards) |
Gene synonyms (human) | ATH1, BHLHA14 |
Gene (mouse) | Atoh1 |
Gene synonyms (mouse) | Ath1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | ATOH1.H12RSNP.1.SM.B |
Gene (human) | ATOH1 (GeneCards) |
Gene synonyms (human) | ATH1, BHLHA14 |
Gene (mouse) | Atoh1 |
Gene synonyms (mouse) | Ath1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 14 |
Consensus | nvbGMCATATGYYn |
GC content | 44.79% |
Information content (bits; total / per base) | 15.371 / 1.098 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 5925 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 2 (14) | 0.868 | 0.891 | 0.738 | 0.775 | 0.802 | 0.847 | 2.391 | 2.778 | 71.398 | 139.06 |
Mouse | 2 (14) | 0.76 | 0.919 | 0.605 | 0.787 | 0.671 | 0.871 | 1.811 | 2.792 | 40.6 | 236.77 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.839 | 0.838 | 0.79 | 0.792 | 0.761 | 0.762 |
best | 0.999 | 0.998 | 0.997 | 0.996 | 0.983 | 0.979 | |
Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.998 | 0.997 | 0.996 | 0.983 | 0.979 |
best | 0.999 | 0.998 | 0.997 | 0.996 | 0.983 | 0.979 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.682 | 0.684 | 0.59 | 0.598 | 0.546 | 0.558 |
best | 0.996 | 0.992 | 0.991 | 0.986 | 0.975 | 0.967 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.969 | 0.905 | 0.95 | 0.621 |
batch 2 | 0.962 | 0.91 | 0.911 | 0.62 |
TF superclass | Basic domains {1} (TFClass) |
TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
TF family | Tal-related {1.2.3} (TFClass) |
TF subfamily | Neurogenin-ATO {1.2.3.4} (TFClass) |
TFClass ID | TFClass: 1.2.3.4.8 |
HGNC | HGNC:797 |
MGI | MGI:104654 |
EntrezGene (human) | GeneID:474 (SSTAR profile) |
EntrezGene (mouse) | GeneID:11921 (SSTAR profile) |
UniProt ID (human) | ATOH1_HUMAN |
UniProt ID (mouse) | ATOH1_MOUSE |
UniProt AC (human) | Q92858 (TFClass) |
UniProt AC (mouse) | P48985 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 2 human, 2 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | ATOH1.H12RSNP.1.SM.B.pcm |
PWM | ATOH1.H12RSNP.1.SM.B.pwm |
PFM | ATOH1.H12RSNP.1.SM.B.pfm |
Alignment | ATOH1.H12RSNP.1.SM.B.words.tsv |
Threshold to P-value map | ATOH1.H12RSNP.1.SM.B.thr |
Motif in other formats | |
JASPAR format | ATOH1.H12RSNP.1.SM.B_jaspar_format.txt |
MEME format | ATOH1.H12RSNP.1.SM.B_meme_format.meme |
Transfac format | ATOH1.H12RSNP.1.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1415.5 | 1785.5 | 1603.5 | 1120.5 |
02 | 1953.25 | 884.25 | 2298.25 | 789.25 |
03 | 326.0 | 3034.0 | 981.0 | 1584.0 |
04 | 2238.0 | 10.0 | 3676.0 | 1.0 |
05 | 3282.0 | 2614.0 | 18.0 | 11.0 |
06 | 0.0 | 5925.0 | 0.0 | 0.0 |
07 | 5925.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 109.0 | 5816.0 |
09 | 5802.0 | 123.0 | 0.0 | 0.0 |
10 | 0.0 | 0.0 | 0.0 | 5925.0 |
11 | 0.0 | 0.0 | 5925.0 | 0.0 |
12 | 2.0 | 1679.0 | 1582.0 | 2662.0 |
13 | 199.0 | 1424.0 | 373.0 | 3929.0 |
14 | 1418.0 | 1731.0 | 1379.0 | 1397.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.239 | 0.301 | 0.271 | 0.189 |
02 | 0.33 | 0.149 | 0.388 | 0.133 |
03 | 0.055 | 0.512 | 0.166 | 0.267 |
04 | 0.378 | 0.002 | 0.62 | 0.0 |
05 | 0.554 | 0.441 | 0.003 | 0.002 |
06 | 0.0 | 1.0 | 0.0 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 0.018 | 0.982 |
09 | 0.979 | 0.021 | 0.0 | 0.0 |
10 | 0.0 | 0.0 | 0.0 | 1.0 |
11 | 0.0 | 0.0 | 1.0 | 0.0 |
12 | 0.0 | 0.283 | 0.267 | 0.449 |
13 | 0.034 | 0.24 | 0.063 | 0.663 |
14 | 0.239 | 0.292 | 0.233 | 0.236 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.045 | 0.187 | 0.079 | -0.279 |
02 | 0.276 | -0.515 | 0.439 | -0.628 |
03 | -1.509 | 0.716 | -0.411 | 0.067 |
04 | 0.412 | -4.803 | 0.908 | -6.148 |
05 | 0.795 | 0.567 | -4.298 | -4.724 |
06 | -6.527 | 1.385 | -6.527 | -6.527 |
07 | 1.385 | -6.527 | -6.527 | -6.527 |
08 | -6.527 | -6.527 | -2.591 | 1.367 |
09 | 1.364 | -2.472 | -6.527 | -6.527 |
10 | -6.527 | -6.527 | -6.527 | 1.385 |
11 | -6.527 | -6.527 | 1.385 | -6.527 |
12 | -5.874 | 0.125 | 0.066 | 0.586 |
13 | -1.998 | -0.039 | -1.375 | 0.975 |
14 | -0.044 | 0.156 | -0.071 | -0.058 |
P-value | Threshold |
---|---|
0.001 | -0.31949 |
0.0005 | 1.65177 |
0.0001 | 5.138615 |