MotifATOH1.H12INVITRO.1.SM.B
Gene (human)ATOH1
(GeneCards)
Gene synonyms (human)ATH1, BHLHA14
Gene (mouse)Atoh1
Gene synonyms (mouse)Ath1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusnvbGMCATATGYYn
GC content44.79%
Information content (bits; total / per base)15.371 / 1.098
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words5925

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (14) 0.868 0.891 0.738 0.775 0.802 0.847 2.391 2.778 71.398 139.06
Mouse 2 (14) 0.76 0.919 0.605 0.787 0.671 0.871 1.811 2.792 40.6 236.77

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.839 0.838 0.79 0.792 0.761 0.762
best 0.999 0.998 0.997 0.996 0.983 0.979
Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.997 0.996 0.983 0.979
best 0.999 0.998 0.997 0.996 0.983 0.979
Non-Methyl HT-SELEX, 3 experiments median 0.682 0.684 0.59 0.598 0.546 0.558
best 0.996 0.992 0.991 0.986 0.975 0.967

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.969 0.905 0.95 0.621
batch 2 0.962 0.91 0.911 0.62
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyNeurogenin-ATO {1.2.3.4} (TFClass)
TFClass IDTFClass: 1.2.3.4.8
HGNCHGNC:797
MGIMGI:104654
EntrezGene (human)GeneID:474
(SSTAR profile)
EntrezGene (mouse)GeneID:11921
(SSTAR profile)
UniProt ID (human)ATOH1_HUMAN
UniProt ID (mouse)ATOH1_MOUSE
UniProt AC (human)Q92858
(TFClass)
UniProt AC (mouse)P48985
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011415.51785.51603.51120.5
021953.25884.252298.25789.25
03326.03034.0981.01584.0
042238.010.03676.01.0
053282.02614.018.011.0
060.05925.00.00.0
075925.00.00.00.0
080.00.0109.05816.0
095802.0123.00.00.0
100.00.00.05925.0
110.00.05925.00.0
122.01679.01582.02662.0
13199.01424.0373.03929.0
141418.01731.01379.01397.0
PFM
ACGT
010.2390.3010.2710.189
020.330.1490.3880.133
030.0550.5120.1660.267
040.3780.0020.620.0
050.5540.4410.0030.002
060.01.00.00.0
071.00.00.00.0
080.00.00.0180.982
090.9790.0210.00.0
100.00.00.01.0
110.00.01.00.0
120.00.2830.2670.449
130.0340.240.0630.663
140.2390.2920.2330.236
PWM
ACGT
01-0.0450.1870.079-0.279
020.276-0.5150.439-0.628
03-1.5090.716-0.4110.067
040.412-4.8030.908-6.148
050.7950.567-4.298-4.724
06-6.5271.385-6.527-6.527
071.385-6.527-6.527-6.527
08-6.527-6.527-2.5911.367
091.364-2.472-6.527-6.527
10-6.527-6.527-6.5271.385
11-6.527-6.5271.385-6.527
12-5.8740.1250.0660.586
13-1.998-0.039-1.3750.975
14-0.0440.156-0.071-0.058
Standard thresholds
P-value Threshold
0.001 -0.31949
0.0005 1.65177
0.0001 5.138615