Motif | ATOH1.H12CORE.0.P.B |
Gene (human) | ATOH1 (GeneCards) |
Gene synonyms (human) | ATH1, BHLHA14 |
Gene (mouse) | Atoh1 |
Gene synonyms (mouse) | Ath1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | ATOH1.H12CORE.0.P.B |
Gene (human) | ATOH1 (GeneCards) |
Gene synonyms (human) | ATH1, BHLHA14 |
Gene (mouse) | Atoh1 |
Gene synonyms (mouse) | Ath1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 10 |
Consensus | RRCAGMTGKb |
GC content | 58.67% |
Information content (bits; total / per base) | 12.361 / 1.236 |
Data sources | ChIP-Seq |
Aligned words | 1001 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 2 (14) | 0.93 | 0.941 | 0.847 | 0.859 | 0.896 | 0.909 | 2.817 | 2.969 | 154.667 | 289.854 |
Mouse | 2 (14) | 0.814 | 0.953 | 0.681 | 0.89 | 0.777 | 0.922 | 2.222 | 3.192 | 89.577 | 477.301 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.83 | 0.798 | 0.78 | 0.763 | 0.757 | 0.743 |
best | 0.984 | 0.969 | 0.976 | 0.959 | 0.974 | 0.955 | |
Methyl HT-SELEX, 1 experiments | median | 0.984 | 0.969 | 0.976 | 0.959 | 0.974 | 0.955 |
best | 0.984 | 0.969 | 0.976 | 0.959 | 0.974 | 0.955 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.685 | 0.649 | 0.595 | 0.587 | 0.554 | 0.554 |
best | 0.974 | 0.948 | 0.965 | 0.94 | 0.961 | 0.933 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.929 | 0.837 | 0.907 | 0.62 |
batch 2 | 0.929 | 0.855 | 0.895 | 0.643 |
TF superclass | Basic domains {1} (TFClass) |
TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
TF family | Tal-related {1.2.3} (TFClass) |
TF subfamily | Neurogenin-ATO {1.2.3.4} (TFClass) |
TFClass ID | TFClass: 1.2.3.4.8 |
HGNC | HGNC:797 |
MGI | MGI:104654 |
EntrezGene (human) | GeneID:474 (SSTAR profile) |
EntrezGene (mouse) | GeneID:11921 (SSTAR profile) |
UniProt ID (human) | ATOH1_HUMAN |
UniProt ID (mouse) | ATOH1_MOUSE |
UniProt AC (human) | Q92858 (TFClass) |
UniProt AC (mouse) | P48985 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 2 human, 2 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | ATOH1.H12CORE.0.P.B.pcm |
PWM | ATOH1.H12CORE.0.P.B.pwm |
PFM | ATOH1.H12CORE.0.P.B.pfm |
Alignment | ATOH1.H12CORE.0.P.B.words.tsv |
Threshold to P-value map | ATOH1.H12CORE.0.P.B.thr |
Motif in other formats | |
JASPAR format | ATOH1.H12CORE.0.P.B_jaspar_format.txt |
MEME format | ATOH1.H12CORE.0.P.B_meme_format.meme |
Transfac format | ATOH1.H12CORE.0.P.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 646.0 | 12.0 | 325.0 | 18.0 |
02 | 385.0 | 110.0 | 505.0 | 1.0 |
03 | 0.0 | 1001.0 | 0.0 | 0.0 |
04 | 1000.0 | 0.0 | 0.0 | 1.0 |
05 | 2.0 | 4.0 | 941.0 | 54.0 |
06 | 417.0 | 453.0 | 130.0 | 1.0 |
07 | 9.0 | 0.0 | 0.0 | 992.0 |
08 | 0.0 | 0.0 | 999.0 | 2.0 |
09 | 2.0 | 139.0 | 616.0 | 244.0 |
10 | 117.0 | 386.0 | 252.0 | 246.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.645 | 0.012 | 0.325 | 0.018 |
02 | 0.385 | 0.11 | 0.504 | 0.001 |
03 | 0.0 | 1.0 | 0.0 | 0.0 |
04 | 0.999 | 0.0 | 0.0 | 0.001 |
05 | 0.002 | 0.004 | 0.94 | 0.054 |
06 | 0.417 | 0.453 | 0.13 | 0.001 |
07 | 0.009 | 0.0 | 0.0 | 0.991 |
08 | 0.0 | 0.0 | 0.998 | 0.002 |
09 | 0.002 | 0.139 | 0.615 | 0.244 |
10 | 0.117 | 0.386 | 0.252 | 0.246 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.944 | -2.91 | 0.26 | -2.547 |
02 | 0.428 | -0.813 | 0.699 | -4.526 |
03 | -4.983 | 1.381 | -4.983 | -4.983 |
04 | 1.38 | -4.983 | -4.983 | -4.526 |
05 | -4.214 | -3.784 | 1.319 | -1.509 |
06 | 0.508 | 0.59 | -0.649 | -4.526 |
07 | -3.157 | -4.983 | -4.983 | 1.372 |
08 | -4.983 | -4.983 | 1.379 | -4.214 |
09 | -4.214 | -0.583 | 0.897 | -0.025 |
10 | -0.753 | 0.431 | 0.007 | -0.017 |
P-value | Threshold |
---|---|
0.001 | 3.325115 |
0.0005 | 4.50704 |
0.0001 | 7.7636 |