MotifATOH1.H12CORE.0.P.B
Gene (human)ATOH1
(GeneCards)
Gene synonyms (human)ATH1, BHLHA14
Gene (mouse)Atoh1
Gene synonyms (mouse)Ath1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusRRCAGMTGKb
GC content58.67%
Information content (bits; total / per base)12.361 / 1.236
Data sourcesChIP-Seq
Aligned words1001

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (14) 0.93 0.941 0.847 0.859 0.896 0.909 2.817 2.969 154.667 289.854
Mouse 2 (14) 0.814 0.953 0.681 0.89 0.777 0.922 2.222 3.192 89.577 477.301

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.83 0.798 0.78 0.763 0.757 0.743
best 0.984 0.969 0.976 0.959 0.974 0.955
Methyl HT-SELEX, 1 experiments median 0.984 0.969 0.976 0.959 0.974 0.955
best 0.984 0.969 0.976 0.959 0.974 0.955
Non-Methyl HT-SELEX, 3 experiments median 0.685 0.649 0.595 0.587 0.554 0.554
best 0.974 0.948 0.965 0.94 0.961 0.933

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.929 0.837 0.907 0.62
batch 2 0.929 0.855 0.895 0.643
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyNeurogenin-ATO {1.2.3.4} (TFClass)
TFClass IDTFClass: 1.2.3.4.8
HGNCHGNC:797
MGIMGI:104654
EntrezGene (human)GeneID:474
(SSTAR profile)
EntrezGene (mouse)GeneID:11921
(SSTAR profile)
UniProt ID (human)ATOH1_HUMAN
UniProt ID (mouse)ATOH1_MOUSE
UniProt AC (human)Q92858
(TFClass)
UniProt AC (mouse)P48985
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01646.012.0325.018.0
02385.0110.0505.01.0
030.01001.00.00.0
041000.00.00.01.0
052.04.0941.054.0
06417.0453.0130.01.0
079.00.00.0992.0
080.00.0999.02.0
092.0139.0616.0244.0
10117.0386.0252.0246.0
PFM
ACGT
010.6450.0120.3250.018
020.3850.110.5040.001
030.01.00.00.0
040.9990.00.00.001
050.0020.0040.940.054
060.4170.4530.130.001
070.0090.00.00.991
080.00.00.9980.002
090.0020.1390.6150.244
100.1170.3860.2520.246
PWM
ACGT
010.944-2.910.26-2.547
020.428-0.8130.699-4.526
03-4.9831.381-4.983-4.983
041.38-4.983-4.983-4.526
05-4.214-3.7841.319-1.509
060.5080.59-0.649-4.526
07-3.157-4.983-4.9831.372
08-4.983-4.9831.379-4.214
09-4.214-0.5830.897-0.025
10-0.7530.4310.007-0.017
Standard thresholds
P-value Threshold
0.001 3.325115
0.0005 4.50704
0.0001 7.7636