ATF7.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF7.H12INVITRO.0.PSM.A
Gene (human)	ATF7 (GeneCards)
Gene synonyms (human)	ATFA
Gene (mouse)	Atf7
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	nnATGACGTCAbn
GC content	47.15%
Information content (bits; total / per base)	15.896 / 1.223
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	2423

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (28)	0.85	0.99	0.831	0.985	0.833	0.994	4.359	7.621	473.44	1185.137
Mouse	1 (5)	0.767	0.802	0.711	0.765	0.745	0.79	2.893	3.25	123.42	219.301

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.748	0.765	0.64	0.637	0.593	0.582
Overall, 3 experiments	best	0.997	0.994	0.989	0.984	0.931	0.927
Methyl HT-SELEX, 1 experiments	median	0.72	0.689	0.64	0.62	0.593	0.582
Methyl HT-SELEX, 1 experiments	best	0.72	0.689	0.64	0.62	0.593	0.582
Non-Methyl HT-SELEX, 2 experiments	median	0.872	0.88	0.801	0.811	0.744	0.753
Non-Methyl HT-SELEX, 2 experiments	best	0.997	0.994	0.989	0.984	0.931	0.927

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	ATF2 {1.1.1.3} (TFClass)
TFClass ID	TFClass: 1.1.1.3.2
HGNC	HGNC:792
MGI	MGI:2443472
EntrezGene (human)	GeneID:11016 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ATF7_HUMAN
UniProt ID (mouse)	ATF7_MOUSE
UniProt AC (human)	P17544 (TFClass)
UniProt AC (mouse)	Q8R0S1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	1

PCM	ATF7.H12INVITRO.0.PSM.A.pcm
PWM	ATF7.H12INVITRO.0.PSM.A.pwm
PFM	ATF7.H12INVITRO.0.PSM.A.pfm
Alignment	ATF7.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	ATF7.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	ATF7.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	ATF7.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	ATF7.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	ATF7.H12INVITRO.0.PSM.A_homer_format_0.001.txt ATF7.H12INVITRO.0.PSM.A_homer_format_0.0005.txt ATF7.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	472.25	565.25	607.25	778.25
02	622.75	419.75	932.75	447.75
03	2014.0	5.0	399.0	5.0
04	0.0	3.0	1.0	2419.0
05	0.0	0.0	2353.0	70.0
06	2423.0	0.0	0.0	0.0
07	0.0	2423.0	0.0	0.0
08	5.0	1.0	2417.0	0.0
09	0.0	8.0	0.0	2415.0
10	670.0	1708.0	27.0	18.0
11	2255.0	26.0	90.0	52.0
12	192.75	961.75	500.75	767.75
13	496.25	687.25	715.25	524.25

PFM

	A	C	G	T
01	0.195	0.233	0.251	0.321
02	0.257	0.173	0.385	0.185
03	0.831	0.002	0.165	0.002
04	0.0	0.001	0.0	0.998
05	0.0	0.0	0.971	0.029
06	1.0	0.0	0.0	0.0
07	0.0	1.0	0.0	0.0
08	0.002	0.0	0.998	0.0
09	0.0	0.003	0.0	0.997
10	0.277	0.705	0.011	0.007
11	0.931	0.011	0.037	0.021
12	0.08	0.397	0.207	0.317
13	0.205	0.284	0.295	0.216

PWM

	A	C	G	T
01	-0.248	-0.069	0.002	0.25
02	0.028	-0.365	0.431	-0.301
03	1.199	-4.471	-0.416	-4.471
04	-5.743	-4.811	-5.328	1.382
05	-5.743	-5.743	1.355	-2.134
06	1.384	-5.743	-5.743	-5.743
07	-5.743	1.384	-5.743	-5.743
08	-4.471	-5.328	1.381	-5.743
09	-5.743	-4.112	-5.743	1.381
10	0.101	1.035	-3.044	-3.417
11	1.312	-3.079	-1.888	-2.422
12	-1.138	0.461	-0.19	0.236
13	-0.199	0.126	0.166	-0.144

Standard thresholds

P-value	Threshold
0.001	0.31671
0.0005	1.983375
0.0001	5.474565