ATF6B.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF6B.H12INVITRO.0.SM.B
Gene (human)	ATF6B (GeneCards)
Gene synonyms (human)	CREBL1, G13
Gene (mouse)	Atf6b
Gene synonyms (mouse)	Crebl1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	nKGATGACGTGRYv
GC content	54.29%
Information content (bits; total / per base)	18.072 / 1.291
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	6800

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.998	0.997	0.994	0.992	0.947	0.944
Overall, 2 experiments	best	0.999	0.999	0.998	0.997	0.969	0.967
Methyl HT-SELEX, 1 experiments	median	0.997	0.996	0.99	0.986	0.925	0.921
Methyl HT-SELEX, 1 experiments	best	0.997	0.996	0.99	0.986	0.925	0.921
Non-Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.998	0.997	0.969	0.967
Non-Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.998	0.997	0.969	0.967

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.948	0.765	0.936	0.611
batch 2	0.817	0.637	0.849	0.678

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	CREB-related {1.1.7} (TFClass)
TF subfamily	ATF6 {1.1.7.3} (TFClass)
TFClass ID	TFClass: 1.1.7.3.2
HGNC	HGNC:2349
MGI	MGI:105121
EntrezGene (human)	GeneID:1388 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ATF6B_HUMAN
UniProt ID (mouse)	ATF6B_MOUSE
UniProt AC (human)	Q99941 (TFClass)
UniProt AC (mouse)	O35451 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ATF6B.H12INVITRO.0.SM.B.pcm
PWM	ATF6B.H12INVITRO.0.SM.B.pwm
PFM	ATF6B.H12INVITRO.0.SM.B.pfm
Alignment	ATF6B.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	ATF6B.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	ATF6B.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	ATF6B.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	ATF6B.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	ATF6B.H12INVITRO.0.SM.B_homer_format_0.001.txt ATF6B.H12INVITRO.0.SM.B_homer_format_0.0005.txt ATF6B.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1504.0	1376.0	2066.0	1854.0
02	609.25	807.25	831.25	4552.25
03	336.0	123.0	6042.0	299.0
04	5028.0	260.0	1504.0	8.0
05	0.0	0.0	0.0	6800.0
06	0.0	0.0	6800.0	0.0
07	6800.0	0.0	0.0	0.0
08	0.0	6800.0	0.0	0.0
09	0.0	0.0	6800.0	0.0
10	0.0	0.0	0.0	6800.0
11	4.0	2953.0	3842.0	1.0
12	2953.0	1.0	3773.0	73.0
13	127.5	5047.5	221.5	1403.5
14	3592.0	1364.0	1068.0	776.0

PFM

	A	C	G	T
01	0.221	0.202	0.304	0.273
02	0.09	0.119	0.122	0.669
03	0.049	0.018	0.889	0.044
04	0.739	0.038	0.221	0.001
05	0.0	0.0	0.0	1.0
06	0.0	0.0	1.0	0.0
07	1.0	0.0	0.0	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.0	1.0	0.0
10	0.0	0.0	0.0	1.0
11	0.001	0.434	0.565	0.0
12	0.434	0.0	0.555	0.011
13	0.019	0.742	0.033	0.206
14	0.528	0.201	0.157	0.114

PWM

	A	C	G	T
01	-0.122	-0.211	0.195	0.087
02	-1.024	-0.743	-0.714	0.984
03	-1.616	-2.61	1.267	-1.732
04	1.084	-1.871	-0.122	-5.117
05	-6.648	-6.648	-6.648	1.385
06	-6.648	-6.648	1.385	-6.648
07	1.385	-6.648	-6.648	-6.648
08	-6.648	1.385	-6.648	-6.648
09	-6.648	-6.648	1.385	-6.648
10	-6.648	-6.648	-6.648	1.385
11	-5.614	0.552	0.815	-6.275
12	0.552	-6.275	0.797	-3.119
13	-2.574	1.087	-2.029	-0.191
14	0.747	-0.22	-0.464	-0.783

Standard thresholds

P-value	Threshold
0.001	-3.086285
0.0005	-0.82021
0.0001	3.32812