ATF6B.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF6B.H12CORE.0.SM.B
Gene (human)	ATF6B (GeneCards)
Gene synonyms (human)	CREBL1, G13
Gene (mouse)	Atf6b
Gene synonyms (mouse)	Crebl1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	nbKRTGACGTSRYv
GC content	54.99%
Information content (bits; total / per base)	15.776 / 1.127
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9665

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.998	0.997	0.992	0.99	0.951	0.946
Overall, 2 experiments	best	0.999	0.999	0.998	0.998	0.977	0.975
Methyl HT-SELEX, 1 experiments	median	0.997	0.996	0.986	0.982	0.925	0.918
Methyl HT-SELEX, 1 experiments	best	0.997	0.996	0.986	0.982	0.925	0.918
Non-Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.998	0.998	0.977	0.975
Non-Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.998	0.998	0.977	0.975

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.954	0.854	0.936	0.601
batch 2	0.859	0.717	0.882	0.72

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	CREB-related {1.1.7} (TFClass)
TF subfamily	ATF6 {1.1.7.3} (TFClass)
TFClass ID	TFClass: 1.1.7.3.2
HGNC	HGNC:2349
MGI	MGI:105121
EntrezGene (human)	GeneID:1388 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ATF6B_HUMAN
UniProt ID (mouse)	ATF6B_MOUSE
UniProt AC (human)	Q99941 (TFClass)
UniProt AC (mouse)	O35451 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ATF6B.H12CORE.0.SM.B.pcm
PWM	ATF6B.H12CORE.0.SM.B.pwm
PFM	ATF6B.H12CORE.0.SM.B.pfm
Alignment	ATF6B.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	ATF6B.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	ATF6B.H12CORE.0.SM.B_jaspar_format.txt
MEME format	ATF6B.H12CORE.0.SM.B_meme_format.meme
Transfac format	ATF6B.H12CORE.0.SM.B_transfac_format.txt
Homer format	ATF6B.H12CORE.0.SM.B_homer_format_0.001.txt ATF6B.H12CORE.0.SM.B_homer_format_0.0005.txt ATF6B.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1985.5	2108.5	2936.5	2634.5
02	1346.5	1428.5	1801.5	5088.5
03	988.0	878.0	6717.0	1082.0
04	5402.0	696.0	3471.0	96.0
05	7.0	37.0	27.0	9594.0
06	2.0	17.0	9620.0	26.0
07	9660.0	0.0	5.0	0.0
08	0.0	9663.0	1.0	1.0
09	0.0	0.0	9665.0	0.0
10	0.0	14.0	1.0	9650.0
11	279.0	4018.0	5329.0	39.0
12	4116.0	71.0	4885.0	593.0
13	682.5	6677.5	707.5	1597.5
14	4737.0	1755.0	1871.0	1302.0

PFM

	A	C	G	T
01	0.205	0.218	0.304	0.273
02	0.139	0.148	0.186	0.526
03	0.102	0.091	0.695	0.112
04	0.559	0.072	0.359	0.01
05	0.001	0.004	0.003	0.993
06	0.0	0.002	0.995	0.003
07	0.999	0.0	0.001	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.0	1.0	0.0
10	0.0	0.001	0.0	0.998
11	0.029	0.416	0.551	0.004
12	0.426	0.007	0.505	0.061
13	0.071	0.691	0.073	0.165
14	0.49	0.182	0.194	0.135

PWM

	A	C	G	T
01	-0.196	-0.136	0.195	0.086
02	-0.584	-0.525	-0.293	0.744
03	-0.893	-1.011	1.022	-0.802
04	0.804	-1.242	0.362	-3.203
05	-5.562	-4.12	-4.414	1.378
06	-6.334	-4.831	1.381	-4.448
07	1.385	-6.961	-5.804	-6.961
08	-6.961	1.385	-6.599	-6.599
09	-6.961	-6.961	1.386	-6.961
10	-6.961	-5.0	-6.599	1.384
11	-2.152	0.508	0.79	-4.07
12	0.532	-3.496	0.703	-1.402
13	-1.262	1.016	-1.226	-0.413
14	0.673	-0.319	-0.255	-0.618

Standard thresholds

P-value	Threshold
0.001	0.10001
0.0005	1.80801
0.0001	5.455815