ATF6A.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ATF6A.H12CORE.0.SM.B
Gene (human)	ATF6 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Atf6
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	nYGATGACGTCAYnn
GC content	49.85%
Information content (bits; total / per base)	19.078 / 1.272
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2449

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.896	0.895	0.826	0.83	0.751	0.761
Overall, 2 experiments	best	1.0	1.0	0.997	0.997	0.919	0.924
Methyl HT-SELEX, 1 experiments	median	0.793	0.789	0.655	0.663	0.582	0.598
Methyl HT-SELEX, 1 experiments	best	0.793	0.789	0.655	0.663	0.582	0.598
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.997	0.997	0.919	0.924
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.997	0.997	0.919	0.924

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	CREB-related {1.1.7} (TFClass)
TF subfamily	ATF6 {1.1.7.3} (TFClass)
TFClass ID	TFClass: 1.1.7.3.1
HGNC	HGNC:791
MGI	MGI:1926157
EntrezGene (human)	GeneID:22926 (SSTAR profile)
EntrezGene (mouse)	GeneID:226641 (SSTAR profile)
UniProt ID (human)	ATF6A_HUMAN
UniProt ID (mouse)	ATF6A_MOUSE
UniProt AC (human)	P18850 (TFClass)
UniProt AC (mouse)	F6VAN0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ATF6A.H12CORE.0.SM.B.pcm
PWM	ATF6A.H12CORE.0.SM.B.pwm
PFM	ATF6A.H12CORE.0.SM.B.pfm
Alignment	ATF6A.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	ATF6A.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	ATF6A.H12CORE.0.SM.B_jaspar_format.txt
MEME format	ATF6A.H12CORE.0.SM.B_meme_format.meme
Transfac format	ATF6A.H12CORE.0.SM.B_transfac_format.txt
Homer format	ATF6A.H12CORE.0.SM.B_homer_format_0.001.txt ATF6A.H12CORE.0.SM.B_homer_format_0.0005.txt ATF6A.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	706.75	523.75	653.75	564.75
02	247.0	448.0	260.0	1494.0
03	181.0	83.0	2098.0	87.0
04	1884.0	154.0	405.0	6.0
05	0.0	1.0	2.0	2446.0
06	0.0	0.0	2449.0	0.0
07	2449.0	0.0	0.0	0.0
08	0.0	2449.0	0.0	0.0
09	0.0	0.0	2449.0	0.0
10	0.0	0.0	0.0	2449.0
11	21.0	2404.0	21.0	3.0
12	2411.0	3.0	22.0	13.0
13	29.0	1111.0	127.0	1182.0
14	497.5	857.5	575.5	518.5
15	514.5	693.5	523.5	717.5

PFM

	A	C	G	T
01	0.289	0.214	0.267	0.231
02	0.101	0.183	0.106	0.61
03	0.074	0.034	0.857	0.036
04	0.769	0.063	0.165	0.002
05	0.0	0.0	0.001	0.999
06	0.0	0.0	1.0	0.0
07	1.0	0.0	0.0	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.0	1.0	0.0
10	0.0	0.0	0.0	1.0
11	0.009	0.982	0.009	0.001
12	0.984	0.001	0.009	0.005
13	0.012	0.454	0.052	0.483
14	0.203	0.35	0.235	0.212
15	0.21	0.283	0.214	0.293

PWM

	A	C	G	T
01	0.143	-0.156	0.065	-0.08
02	-0.903	-0.311	-0.852	0.89
03	-1.211	-1.978	1.229	-1.932
04	1.122	-1.371	-0.412	-4.347
05	-5.752	-5.338	-5.046	1.383
06	-5.752	-5.752	1.384	-5.752
07	1.384	-5.752	-5.752	-5.752
08	-5.752	1.384	-5.752	-5.752
09	-5.752	-5.752	1.384	-5.752
10	-5.752	-5.752	-5.752	1.384
11	-3.287	1.365	-3.287	-4.821
12	1.368	-4.821	-3.244	-3.716
13	-2.988	0.594	-1.561	0.656
14	-0.207	0.336	-0.062	-0.166
15	-0.173	0.124	-0.156	0.158

Standard thresholds

P-value	Threshold
0.001	-2.50649
0.0005	-0.67834
0.0001	3.43181